GSK 2330672

Product Name: GSK 2330672
CAS No.: 1345982-69-5
Chemical Name: GSK 2330672
Synonyms: linerixibat;CS-2639;GSK 2330672;Iinerixibat;linerixibat (GSK2330672);GSK 2330672; GSK-2330672;Iinerixibat (GSK2330672);3-((((3R,5R)-3-Butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[f][1,4]thiazepin-8-yl)methyl)amino)pentanedioic acid;Pentanedioic acid, 3-((((3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4-benzothiazepin-8-yl)methyl)amino)-;3-[[(3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxo-5-phenyl-4,5-dihydro-2H-1λ6,4-benzothiazepin-8-yl]methylamino]pentanedioic acid
CBNumber: CB12716247
Molecular Formula: C28H38N2O7S
Formula Weight: 546.68
MOL File: 1345982-69-5.mol

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GSK 2330672 Property

Boiling point:: 730.8±60.0 °C(Predicted)
Density: 1.218±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 5 mg/ml; DMSO: 2 mg/ml; PBS (pH 7.2): 0.2 mg/ml
form: A crystalline solid
pka: 3.27±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H401Toxic to aquatic life

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 23843
Product name: GSK2330672
Purity: ≥98%
Packaging: 1mg
Price: $110
Updated: 2024/03/01

Cayman Chemical

Product number: 23843
Product name: GSK2330672
Purity: ≥98%
Packaging: 5mg
Price: $515
Updated: 2024/03/01

Cayman Chemical

Product number: 23843
Product name: GSK2330672
Purity: ≥98%
Packaging: 10mg
Price: $918
Updated: 2024/03/01

AK Scientific

Product number: 4578DL
Product name: Linerixibat
Packaging: 5mg
Price: $671
Updated: 2021/12/16

Crysdot

Product number: CD31003808
Product name: GSK2330672
Purity: 98+%
Packaging: 5mg
Price: $208
Updated: 2021/12/16

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GSK 2330672 Chemical Properties,Usage,Production

Description

GSK2330672 is an inhibitor of the apical sodium-dependent bile acid transporter (ASBT; IC₅₀s = 42, 2.1, and 1.9 nM for human, mouse, and rat ASBT, respectively). In vivo, GSK2330672 (0.05 mg/kg) stimulates fecal bile acid secretion, reduces hemoglobin A1c (HbA1c) and plasma glucose levels, and increases total GLP-1 and plasma insulin in Zucker diabetic fatty (ZDF) rats.

GSK 2330672 Preparation Products And Raw materials

Raw materials

Preparation Products

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GSK 2330672 Suppliers

China 58 United States 9 Global 67

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
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Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19179
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Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
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ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
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Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4574
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Hui Chem Co., Ltd.

Tel: 021-34799779 18918539052
Fax: 021-61916468
Email: 1879902218@qq.com
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SPIRO PHARMA

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Qingdao IniKem BioPharmaTech Co.,Ltd

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Email: sales@inikem.com
Country: China
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ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
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Email: 2853530910@QQ.com
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1345982-69-5, GSK 2330672Related Search:

GSK2814338 GSK-2256098 GSK-25 S)-1-(sec-butyl)-N-((4,6-diMethyl-2-oxo-1,2-dihydropyridin-3-yl)Methyl)-3-Methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxaMide 7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine GSK 2801 GSK2636771 GSK2879552 GSK2795039 GSK2838232

GSK 2330672; GSK-2330672

GSK 2330672

3-[[(3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxo-5-phenyl-4,5-dihydro-2H-1λ<sup>6</sup>,4-benzothiazepin-8-yl]methylamino]pentanedioic acid

Pentanedioic acid, 3-((((3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4-benzothiazepin-8-yl)methyl)amino)-

CS-2639

Iinerixibat

linerixibat

Iinerixibat (GSK2330672)

type-2,PBC,lipid-lowering,solubility,nonabsorbable,GSK-2330672,Inhibitor,Primary,diabetes,GSK 2330672,Cholangitis,inhibit,Linerixibat,aqueous,Biliary,ASBT

linerixibat (GSK2330672)

3-((((3R,5R)-3-Butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[f][1,4]thiazepin-8-yl)methyl)amino)pentanedioic acid

1345982-69-5