ChemicalBook > CAS DataBase List > 1,5-DIAMINO-3-OXAPENTANE

1,5-DIAMINO-3-OXAPENTANE

Product Name
1,5-DIAMINO-3-OXAPENTANE
CAS No.
2752-17-2
Chemical Name
1,5-DIAMINO-3-OXAPENTANE
Synonyms
2,2'-Oxydiethanamine;2-(2-aminoethoxy)ethanamine;EDR 104;Oxyamine Ether;Amino-PEG1-Amine;2,2'-Oxybis(ethyL;Jeffamine EDR 104;2,2'-OXYDIETHYLAMINE;2,2’-oxybis-ethanamin;Di(2-aminoethyl) ether
CBNumber
CB1285190
Molecular Formula
C4H12N2O
Formula Weight
104.15
MOL File
2752-17-2.mol
More
Less

1,5-DIAMINO-3-OXAPENTANE Property

Boiling point:
69-71 °C (15 mmHg)
Density 
0,98 g/cm3
vapor pressure 
2.39hPa at 20℃
refractive index 
1.455-1.458
storage temp. 
2-8°C(protect from light)
form 
Liquid
pka
pK1: 8.62(+2);pK2: 9.59(+1) (30°C)
color 
Clear colorless
Water Solubility 
100g/L at 20℃
InChI
InChI=1S/C4H12N2O/c5-1-3-7-4-2-6/h1-6H2
InChIKey
GXVUZYLYWKWJIM-UHFFFAOYSA-N
SMILES
O(CCN)CCN
LogP
-2.12 at 22℃
CAS DataBase Reference
2752-17-2
EPA Substance Registry System
Ethanamine, 2,2'-oxybis- (2752-17-2)
More
Less

Safety

Hazard Codes 
C
Risk Statements 
34-41
Safety Statements 
45-36/37/39-26-39
RIDADR 
UN 2735 8/PG III
HazardClass 
8
PackingGroup 
III
HS Code 
29221990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
O0278
Product name
2,2'-Oxybis(ethylamine)
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$261
Updated
2025/07/31
TCI Chemical
Product number
O0278
Product name
2,2'-Oxybis(ethylamine)
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$745
Updated
2025/07/31
TCI Chemical
Product number
O0278
Product name
2,2'-Oxybis(ethylamine)
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$2037
Updated
2025/07/31
TRC
Product number
E588923
Product name
2,2''-Oxydiethanamine
Packaging
100mg
Price
$75
Updated
2021/12/16
BroadPharm
Product number
BP-23107
Product name
Amino-PEG1-amine
Purity
98%
Packaging
1g
Price
$65
Updated
2021/12/16
More
Less

1,5-DIAMINO-3-OXAPENTANE Chemical Properties,Usage,Production

Description

Amino-PEG1-Amine is a water soluble PEG linker containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

Chemical Properties

clear colorless liquid

Uses

2,2''-Oxydiethanamine is a coating resin modifier.

Definition

ChEBI: Diamino-poly(ethylene glycol) is a poly(ethylene glycol) terminated with -NH2 groups. It is a poly(ethylene glycol) derivative and a primary amino compound.

Flammability and Explosibility

Not classified

Synthesis

43113-25-3

2752-17-2

General procedure for the synthesis of 2,2'-oxydiethylamine from 2,2'-(oxybis(ethane-2,1-diyl))bis(isoindoline-1,3-dione): the raw material (575 mg, 0.83 mmol) was mixed with 80% hydrazine hydrate (8.3 mmol) in chloroform (10 mL) with reflux stirring for 4 hours. After completion of the reaction, the reaction mixture was treated with water and extracted with chloroform. The organic layer was dried with magnesium sulfate followed by evaporation of the solvent. Purification by distillation afforded the target product 2,2'-oxy diethylamine (9a) in 93% yield; boiling point 75-79°C/5 mmHg (literature value 31: 55-60°C/2 mmHg). The structure of the product was confirmed by 1H NMR (500 MHz, DMSO-d6) δ 8.31 (4H, br s), 3.32 (4H, t, J = 5.5 Hz), 2.63 (4H, t, J = 5.5 Hz); 13C NMR (500 MHz, DMSO-d6) δ 72.7, 41.3; and mass spectrum (FAB) m/z: 105 [ M + H] for confirmation.

References

[1] Tetrahedron, 2016, vol. 72, # 29, p. 4258 - 4272
[2] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982, vol. 18, # 2, p. 193 - 196
[3] Khimiya Geterotsiklicheskikh Soedinenii, 1982, # 2, p. 246 - 249
[4] Journal of Organic Chemistry USSR (English Translation), 1980, vol. 16, p. 1124 - 1129
[5] Zhurnal Organicheskoi Khimii, 1980, vol. 16, # 6, p. 1301 - 1307

1,5-DIAMINO-3-OXAPENTANE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1,5-DIAMINO-3-OXAPENTANE Suppliers

Americas 1 Belgium 3 China 133 Europe 1 France 1 Germany 4 India 3 Japan 2 Switzerland 2 The Netherlands 1 United Kingdom 7 United States 26 Global 184
Lianyungang City and Rui Technology Co., Ltd.
Tel
015162260526; 15162260526
Fax
051885593298
Email
sales@henrychem.com
Country
China
ProdList
300
Advantage
58
Nanjing Junnahe Biopharmaceutical Co., Ltd
Tel
025-58367986 17351780683
Fax
QQ3209878052
Email
amy.xiang@ally-chem.com
Country
China
ProdList
354
Advantage
60
Henan Mengtai Pharmaceutical Technology Co., Ltd
Tel
176345344 7 17634854698
Email
1959525201@qq.com
Country
China
ProdList
10000
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Wuhan Taiyicheng Biopharmaceutical Co., Ltd.
Tel
027-88320699
Fax
027-88320962
Email
tycshyy@126.com
Country
China
ProdList
297
Advantage
66
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq：2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Xingui Biotechnology Co., Ltd.
Tel
15121041756
Email
xingui2022@126.com
Country
China
ProdList
9979
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15873
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Jinan Putubio Tech Co., Ltd.
Tel
+86 (531) 8099-2215
Fax
+86 (531) 8099-2215
Email
putubio@outlook.com
Country
China
ProdList
1261
Advantage
55
Shanghai Haozhixiang Biotechnology Co., Ltd
Tel
526763801 13301653310
Fax
+86-21-51619052
Email
526763801@qq.com
Country
China
ProdList
9274
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Chengdu Huachun Technology Co., Ltd
Tel
400-1166-196 15982826727
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Nanjing Ally Chemical S&T Co., Ltd.
Tel
025-025-58367986 18913956109
Fax
QQ:3209878052
Email
amy.xiang@ally-chem.com
Country
China
ProdList
567
Advantage
58
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28785
Advantage
58
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
10007
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19800
Advantage
60
Shanghai Zhen Li Biological Technology Co., Ltd
Tel
021-16621358918; 18516310516
Fax
13045646768
Email
zhenlipharma888@163.com
Country
China
ProdList
19035
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Bejing Famous Pharmaceutical Technology Co., Ltd.
Tel
13331045123
Fax
86-10-80339217
Email
2559355526@qq.com
Country
China
ProdList
14193
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Henan Aosman Biotechnology Co., LTD
Tel
0371-0371-61318675 17719817155
Fax
0371-61318675
Email
sales@xlinebio.com
Country
China
ProdList
2857
Advantage
58
3A Chemicals
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20557
Advantage
58
Shanghai SPAR pharmaceutical technology co., LTD
Tel
021-000000 13917643586;
Email
admin@jingshipharmatech.com
Country
China
ProdList
9859
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-63315541 13323832564
Fax
QQ:3001332135
Email
3001332135@qq.com
Country
China
ProdList
9972
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Alpha Biopharmaceuticals Co., Ltd
Tel
0411-39042497
Fax
0411-39042693
Email
sales@alphabiopharm.com
Country
China
ProdList
1951
Advantage
58
Shanghai Han-Xiang Chemical Co., Ltd.
Tel
15971444841
Fax
18327183813
Email
amber@biochempartner.com
Country
China
ProdList
3061
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Beijing Minruida Technology Co., Ltd.
Tel
010-82387566 18001021521;
Fax
82387566-801
Email
sales@mreda.com.cn
Country
China
ProdList
10083
Advantage
58
Hunan chemfish Scientific co.,ltd
Tel
19313119705 15707487186
Email
sales@chemfish.com
Country
China
ProdList
4960
Advantage
58
Chengdu Forest Science and Technology Development Co,. Ltd
Tel
028-87925786 18010564218
Fax
028-61777050
Email
vendi@cdforestchem.com
Country
China
ProdList
1992
Advantage
58
Zhengzhou Alfa Chemical Co.,Ltd
Tel
+8618530059196
Email
sale04@alfachem.cn
Country
China
ProdList
11834
Advantage
58

2752-17-2, 1,5-DIAMINO-3-OXAPENTANERelated Search:

GLYCYL-DL-THREONINE Actinomycin D ALPHA-ERGOCRYPTINE BEAUVERICIN Neomycin sulfate VALINOMYCIN RIBOSTAMYCIN SULFATE SALT (1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL KRYPTOFIX(R) 221 1,4,10-TRIOXA-7,13-DIAZACYCLOPENTADECANE DIHYDROERGOTAMINE TARTRATE 2,2'-OXYBIS(ETHYLAMINE) DIHYDROCHLORIDE Sisomicin DL-2-AMINOPROPIONIC ANHYDRIDE 1,8-Diamino-3,6-dioxaoctane KRYPTOFIX(R) 211 CALCIUM IONOPHORE II BUTIROSIN DISULFATE

  • 2,2’-oxybis-ethanamin
  • 2,2'-OXYDIETHYLAMINE
  • 2,2'-DIAMINODIETHYL ETHER
  • 10-chloro-5H-phenanthridin-6-one
  • 2,2'-Oxybis(ethyL
  • 1,5-DIAMINO-3-OXAPENTANE
  • BIS(2-AMINOETHYL) ETHER
  • 1,5-DIAMINO-3-OXAPENTANE 98%
  • 2,2'-Oxybis(ethanamine)
  • 2,2'-Oxydiethanamine
  • 3-Oxapentane-1,5-diamine
  • Di(2-aminoethyl) ether
  • 2,2'-Oxybis(ethylamine),98%
  • Bis(2-aminoethyl) Ether 2,2'-Diaminodiethyl Ether 2,2'-Oxydiethylamine
  • 2-(2-Aminoethoxy)ethylamine
  • Amino-PEG1-Amine
  • 2-(2-aminoethoxy)ethanamine
  • 2-(2-aminoethoxy)ethan-1-amine
  • EDR 104
  • Jeffamine EDR 104
  • 3-Oxa-1,5-pentanediamine
  • Ethanamine, 2,2'-oxybis-
  • 2,2'-Oxybis(ethylamine)&gt
  • ,2'-Oxybis(ethylamine)
  • Oxyamine Ether
  • 2,2'-oxybis(ethan-1-amine)
  • 2,2'-Oxybis(ethylamine)
  • 2,2'-oxydi(ethylamine)
  • 2,2'-Oxydiethanamine , 2,2-Oxybis(ethylamine)
  • 2,2′-Oxybis(ethylamine), CAS 2752-17-2
  • 2,2'-Oxybis(ethylamine)
  • 2752-17-2
  • 1