Isopropyl acetoacetate

Product Name: Isopropyl acetoacetate
CAS No.: 542-08-5
Chemical Name: Isopropyl acetoacetate
Synonyms: IPAA;Isopropylacetoactetate;ACIP;Isopropylacetoacetat;Isopropyl acetoaceta;ISOPROPYL ACETOACETATE;Isopropyl3-oxobutyrate;Isopropyl3-oxobutanoate;IsopropylAcetoacetate>Isopropylacetoacetate,98%
CBNumber: CB1293982
Molecular Formula: C7H12O3
Formula Weight: 144.17
MOL File: 542-08-5.mol

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Isopropyl acetoacetate Property

Melting point:: -27°C
Boiling point:: 95 °C52 hPa(lit.)
Density: 0.989 g/mL at 20 °C(lit.)
refractive index: n20/D 1.418
Flash point:: 73°C
solubility: Chloroform, Ethyl Acetate, Methanol, Toluene,
pka: 11.67±0.46(Predicted)
form: Colourless Liquid
color: Colorless to Almost colorless
Water Solubility: Slightly miscible with water.
Merck: 14,5206
BRN: 1757046
InChIKey: GVIIRWAJDFKJMJ-UHFFFAOYSA-N
LogP: 1.060 (est)
CAS DataBase Reference: 542-08-5(CAS DataBase Reference)
EPA Substance Registry System: Butanoic acid, 3-oxo-, 1-methylethyl ester (542-08-5)

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Safety

Hazard Codes: Xi
Risk Statements: 38
Safety Statements: 26-36-24/25
WGK Germany: 1
TSCA: Yes
HS Code: 29183000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 689092
Product name: Isopropyl acetoacetate
Purity: Lonza quality, ≥99.0% (GC)
Packaging: 1kg
Price: $151
Updated: 2024/03/01

Sigma-Aldrich

Product number: 689092
Product name: Isopropyl acetoacetate
Purity: Lonza quality, ≥99.0% (GC)
Packaging: 25kg
Price: $2510
Updated: 2024/03/01

TCI Chemical

Product number: I0826
Product name: Isopropyl Acetoacetate
Purity: >97.0%(GC)
Packaging: 25g
Price: $38
Updated: 2024/03/01

TCI Chemical

Product number: I0826
Product name: Isopropyl Acetoacetate
Purity: >97.0%(GC)
Packaging: 500g
Price: $469
Updated: 2024/03/01

Alfa Aesar

Product number: A11907
Product name: Isopropyl acetoacetate
Purity: 98%
Packaging: 50g
Price: $37
Updated: 2023/06/20

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Isopropyl acetoacetate Chemical Properties,Usage,Production

Chemical Properties

Colourless Liquid

Uses

Isopropyl acetoacetate (IPAA) is used as intermediate for chemical synthesis. Product Data Sheet

Uses

Isopropyl acetoacetate is used as an intermediate for the manufacturing of agrochemicals and pharmaceutical products such as isradipine.

Application

Isopropyl acetoacetate can be used as a reactant to synthesize:
Isopropyl 2-acetyl-3-phenyl-2-propenoate via Knoevenagel reaction in the presence of Ti(O-i-Pr)4.
Substituted 1,4-dihydropyridines by reacting with cinnamaldehydes and primary amines.
5-Isopropoxycarbonyl-6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-thione via Biginelli reaction with benzaldehyde and thiourea.

Synthesis Reference(s)

The Journal of Organic Chemistry, 26, p. 225, 1961 DOI: 10.1021/jo01060a055

Isopropyl acetoacetate Preparation Products And Raw materials

Raw materials

Preparation Products

Nimodipine Isradipine Isopropyl 3-aminocrotonate PROPETAMPHOS

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Isopropyl acetoacetate Suppliers

Americas 1 Belgium 1 Brazil 1 Canada 1 China 257 Europe 1 Germany 3 India 11 Japan 4 Slovakia 1 Spain 1 Switzerland 3 United Kingdom 7 United States 21 USA 1 Global 314

Hubei deante Chemical Technology Co., Ltd

Tel: 15927262683
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Hubei Hongxin Ruiyu Fine Chemical Co., Ltd.

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ProdList: 2006
Advantage: 55

Henan Duobei Chemical Co., Ltd

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BTC Pharmaceutical CO. Ltd

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Country: China
ProdList: 696
Advantage: 55

Hubei Wande Chemical Co., Ltd

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ProdList: 9955
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
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Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
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ProdList: 24529
Advantage: 81

Beijing dtftchem Technology Co., Ltd.

Tel: 010-60275820 13031183356
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Energy Chemical

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Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

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View Lastest Price from Isopropyl acetoacetate manufacturers

Hubei Yiling biotechnology Co Ltd

Product: Isopropyl acetoacetate 542-08-5
Price: US $0.00/G/KG
Min. Order: 1G/KG
Purity: 99%
Supply Ability: 100MT
Release date: 2025-02-14

Hebei Mujin Biotechnology Co.,Ltd

Product: Isopropyl acetoacetate 542-08-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-08-29

Hebei Weibang Biotechnology Co., Ltd

Product: Isopropyl acetoacetate 542-08-5
Price: US $8.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-28

542-08-5, Isopropyl acetoacetateRelated Search:

Isopropyl acetate Isopropyl chloroacetate Isopropyl bromoacetate Isopropyl myristate Titanium tetraisopropanolate (2-Propenyl) 3-oxobutanoate Diisopropyl azodicarboxylate Isopropyl alcohol Acetoacetic Acid Isopropyl palmitate Isopropyl salicylate Isopropyl 2-cyanoacetate ISOPROPYL LAURATE tert-Butyl acetoacetate Acetylsalicylic acid 1,3,5,2,4,6-triazatriphosphorine, 2-ethoxy-2,4,4,6,6-pentafluoro-2,2,4,4,6,6-hexahydro- Ethyl 2-(ethoxymethylene)-4,4,4-trifluoroacetoacetate Ethyl acetohydroxamate

3-oxo-butanoicaci1-methylethylester

3-Oxobutansαure-1-methylethylester

3-Oxo-butyricacidisopropylester

Acetoaceticacid,isopropylester

acetoaceticacidisopropylester

Butanoicacid,3-oxo-,1-methylethylester

3-oxobutanoic acid propan-2-yl ester

Isopropyl3-oxobutanoate

Isopropyl3-oxobutyrate

ISOPROPYL ACETOACETATE

ACIP

Isopropyl acetoacetate(IPAA)

ISOPROPYL ACETOACETATE, WACKER QUALITY

IPAA

Isopropylacetoactetate

Isopropylacetoacetate,98%

Isopropylacetoacetat

3-oxo-butanoic acid 1-methylethyl ester

1-methyl-3-oxo-butanoic acid ethyl ester

3-Oxobutanoic acid isopropyl ester

3-ketobutyric acid isopropyl ester

Isopropyl acetoaceta

Acetoacetic Acid Isopropyl Ester Isopropyl 3-Oxobutyrate 3-Oxobutyric Acid Isopropyl Ester

IsopropylAcetoacetate&gt

TIANFU-CHEM - Isopropyl acetoacetate

Isopropyl Acetoacetate, ≥ 97.0%

542-08-5

524-08-5

CH3COCH2COOCHCH32

Esters

Building Blocks

C6 to C7

Carbonyl Compounds

Organic Building Blocks

Miscellaneous Reagents

C6 to C7

Carbonyl Compounds

Esters

bc0001