2-Bromo-4-chloroaniline
- Product Name
- 2-Bromo-4-chloroaniline
- CAS No.
- 873-38-1
- Chemical Name
- 2-Bromo-4-chloroaniline
- Synonyms
- 2-Bromo-4-chlorobenzenamine;2-Bromo-4-chL;2-Bromo-4-chlroaniline;4-Chloro-2-Bromoanilin;2-BROMO-4-CHLOROANILINE;4-Chloro-2-Bromoaniline;4-methoxy-2-bromo aniline;2-Bromo-4-chloroaniline 99%;2-Bromo-4-chloroaniline >2-Bromo-4-chloroaniline,98%
- CBNumber
- CB1297708
- Molecular Formula
- C6H5BrClN
- Formula Weight
- 206.47
- MOL File
- 873-38-1.mol
2-Bromo-4-chloroaniline Property
- Melting point:
- 64-68 °C (lit.)
- Boiling point:
- 127°C 14mm
- Density
- 1.722±0.06 g/cm3(Predicted)
- Flash point:
- 127°C/20mm
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- soluble in Methanol
- pka
- 1.90±0.10(Predicted)
- form
- Crystalline Powder
- color
- Pale brown
- BRN
- 2802563
- InChI
- InChI=1S/C6H5BrClN/c7-5-3-4(8)1-2-6(5)9/h1-3H,9H2
- InChIKey
- SYTBIFURTZACKR-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(Cl)C=C1Br
- CAS DataBase Reference
- 873-38-1(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-Bromo-4-chloroaniline(873-38-1)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
H302Harmful if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P309IF exposed or if you feel unwell:
P310Immediately call a POISON CENTER or doctor/physician.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B2268
- Product name
- 2-Bromo-4-chloroaniline
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $35
- Updated
- 2025/07/31
- Product number
- B2268
- Product name
- 2-Bromo-4-chloroaniline
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $105
- Updated
- 2025/07/31
- Product number
- B678940
- Product name
- 2-Bromo-4-chlroaniline
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- B678940
- Product name
- 2-Bromo-4-chlroaniline
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- JK356754
- Product name
- 2-Bromo-4-chloroaniline
- Purity
- 98%
- Packaging
- 5g
- Price
- $61
- Updated
- 2021/12/16
2-Bromo-4-chloroaniline Chemical Properties,Usage,Production
Chemical Properties
Pale brown crystalline powder
Uses
2-Bromo-4-chloroaniline may be used in the preparation of:
- 2-bromo-4-chloro-N-tosylaniline
- 2-bromo-4-chlorothiophenol
- 7-chloro-4a-methyl-4,4a,9,9a-tetrahydro-1H-carbazol-2(3H)-one
General Description
2-Bromo-4-chloroaniline is a 2-bromo-4-substituted aniline that can be prepared from 4-chloroaniline via electrophilic bromination.
Synthesis
106-47-8
873-38-1
General procedure for the synthesis of 2-bromo-4-chloroaniline from 4-chloroaniline: To a mixture of 4-chloroaniline (0.7 mmol) was added a dichloromethane (30 ml)-methanol (15 ml) solution of brominating agent (1) (0.72 g, 0.7 mmol). The reaction mixture was stirred at room temperature until decolorization of the orange solution occurred. The progress of the reaction was monitored by thin layer chromatography (TLC) (eluent: hexane/ethyl acetate, 7:3). After completion of the reaction, the solvent was evaporated and ether (10 ml) was added to the residue. The supernatant was decanted and the insoluble residue was washed with ether (3 x 10 ml). The combined organic extracts were dried over anhydrous magnesium sulfate and the solvent was evaporated under vacuum to give the crude product 2-bromo-4-chloroaniline. The crude product was further purified by silica gel fast column chromatography (hexane/ethyl acetate, 7:3).
References
[1] Synthetic Communications, 2009, vol. 39, # 2, p. 215 - 219
[2] Tetrahedron Letters, 2006, vol. 47, # 49, p. 8693 - 8697
[3] Canadian Journal of Chemistry, 2005, vol. 83, # 2, p. 146 - 149
[4] Synthetic Communications, 2010, vol. 40, # 5, p. 647 - 653
[5] Tetrahedron Letters, 2005, vol. 46, # 51, p. 8959 - 8963
2-Bromo-4-chloroaniline Preparation Products And Raw materials
Raw materials
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View Lastest Price from 2-Bromo-4-chloroaniline manufacturers
- Product
- 2-Bromo-4-chloroaniline 873-38-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-06-06
- Product
- 2-Bromo-4-chloroaniline 873-38-1
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-05
- Product
- 2-Bromo-4-chloroaniline 873-38-1
- Price
- US $20.00-1.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-10-24