2-Bromo-4-fluoroaniline
- Product Name
- 2-Bromo-4-fluoroaniline
- CAS No.
- 1003-98-1
- Chemical Name
- 2-Bromo-4-fluoroaniline
- Synonyms
- 2-BROMO-4-FLUORO-PHENYLAMINE;Bromofluoroaniline1;2-Bromo-4-fluoroanil;4-FLUORO-2-BROMOANILINE;2-BROMO-4-FLUOROANILINE;2-Bromo-4-fluoroaniline99%;2-Bromo-4-fluoroaniline >2-Bromo-4-fluoroaniline 99%;2-BROMO-4-FLUOROANILINE 98+%;2-Bromo-4-fluoroaniline, 95%
- CBNumber
- CB1402890
- Molecular Formula
- C6H5BrFN
- Formula Weight
- 190.01
- MOL File
- 1003-98-1.mol
2-Bromo-4-fluoroaniline Property
- Melting point:
- 41
- Boiling point:
- 221 °C (lit.)
- Density
- 1.67 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.583(lit.)
- Flash point:
- 220 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 2.60±0.10(Predicted)
- form
- Liquid
- color
- Clear yellow-brown
- Specific Gravity
- 1.670
- BRN
- 2802562
- InChI
- InChI=1S/C6H5BrFN/c7-5-3-4(8)1-2-6(5)9/h1-3H,9H2
- InChIKey
- YLMFXCIATJJKQL-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(F)C=C1Br
- CAS DataBase Reference
- 1003-98-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 369055
- Product name
- 2-Bromo-4-fluoroaniline
- Purity
- 97%
- Packaging
- 5g
- Price
- $25.2
- Updated
- 2023/01/07
- Product number
- B1829
- Product name
- 2-Bromo-4-fluoroaniline
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $30
- Updated
- 2025/07/31
- Product number
- B1829
- Product name
- 2-Bromo-4-fluoroaniline
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $95
- Updated
- 2025/07/31
- Product number
- B678945
- Product name
- 2-Bromo-4-fluoroaniline
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- PC1397
- Product name
- 2-Bromo-4-fluoroaniline
- Purity
- 99%
- Packaging
- 100g
- Price
- $48
- Updated
- 2021/12/16
2-Bromo-4-fluoroaniline Chemical Properties,Usage,Production
Uses
2-Bromo-4-fluoroaniline is an organic compound that is an aniline derivative. It is mainly used as an organic synthesis reagent in experimental research.
Chemical Properties
Clear yellow-brown liquid
General Description
2-Bromo-4-fluoroaniline is an aryl fluorinated building block.
Synthesis
371-40-4
1003-98-1
The general procedure for the synthesis of 2-bromo-4-fluoroaniline from 4-fluoroaniline was as follows: 200 mL of distilled N,N-dimethylformamide (DMF) and 4-fluoroaniline (8.64 mL, 58.13 mmol) were added to a two-necked flask equipped with a stirring device. N-bromosuccinimide (11.4 g, 63.95 mmol) dissolved in DMF was added slowly and dropwise with stirring. After completion of the reaction, extraction was carried out using dichloromethane (CH2Cl2). The product was purified by column chromatography (eluent ratio of ethyl acetate: n-hexane = 1:4), and the target product 2-bromo-4-fluoroaniline was finally obtained in 95% yield.
References
[1] Patent: KR2018/50795, 2018, A. Location in patent: Paragraph 0134; 0135; 0152-0154
[2] Tetrahedron Letters, 2000, vol. 41, # 13, p. 2083 - 2085
[3] Journal of the American Chemical Society, 2011, vol. 133, # 18, p. 6868 - 6870
[4] Chemistry - A European Journal, 2011, vol. 17, # 49, p. 13665 - 13669
[5] Tetrahedron Letters, 2014, vol. 55, # 38, p. 5338 - 5341
2-Bromo-4-fluoroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Bromo-4-fluoroaniline manufacturers
- Product
- 2-Bromo-4-fluoroaniline 1003-98-1
- Price
- US $40.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-09-07
- Product
- 2-Bromo-4-fluoroaniline 1003-98-1
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-19
- Product
- 2-Bromo-4-fluoroaniline 1003-98-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000KG
- Release date
- 2024-07-12