ChemicalBook > CAS DataBase List > 2-Bromo-4-fluoroaniline

2-Bromo-4-fluoroaniline

Product Name
2-Bromo-4-fluoroaniline
CAS No.
1003-98-1
Chemical Name
2-Bromo-4-fluoroaniline
Synonyms
2-BROMO-4-FLUORO-PHENYLAMINE;Bromofluoroaniline1;2-Bromo-4-fluoroanil;4-FLUORO-2-BROMOANILINE;2-BROMO-4-FLUOROANILINE;2-Bromo-4-fluoroaniline99%;2-Bromo-4-fluoroaniline >2-Bromo-4-fluoroaniline 99%;2-BROMO-4-FLUOROANILINE 98+%;2-Bromo-4-fluoroaniline, 95%
CBNumber
CB1402890
Molecular Formula
C6H5BrFN
Formula Weight
190.01
MOL File
1003-98-1.mol
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2-Bromo-4-fluoroaniline Property

Melting point:
41
Boiling point:
221 °C (lit.)
Density 
1.67 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.583(lit.)
Flash point:
220 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
2.60±0.10(Predicted)
form 
Liquid
color 
Clear yellow-brown
Specific Gravity
1.670
BRN 
2802562
InChI
InChI=1S/C6H5BrFN/c7-5-3-4(8)1-2-6(5)9/h1-3H,9H2
InChIKey
YLMFXCIATJJKQL-UHFFFAOYSA-N
SMILES
C1(N)=CC=C(F)C=C1Br
CAS DataBase Reference
1003-98-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,T
Risk Statements 
36/37/38
Safety Statements 
26-37/39
RIDADR 
UN2810
WGK Germany 
3
Hazard Note 
Toxic
HazardClass 
6.1
PackingGroup 
III
HS Code 
29214200
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
369055
Product name
2-Bromo-4-fluoroaniline
Purity
97%
Packaging
5g
Price
$25.2
Updated
2023/01/07
TCI Chemical
Product number
B1829
Product name
2-Bromo-4-fluoroaniline
Purity
>98.0%(GC)
Packaging
5g
Price
$30
Updated
2025/07/31
TCI Chemical
Product number
B1829
Product name
2-Bromo-4-fluoroaniline
Purity
>98.0%(GC)
Packaging
25g
Price
$95
Updated
2025/07/31
TRC
Product number
B678945
Product name
2-Bromo-4-fluoroaniline
Packaging
1g
Price
$45
Updated
2021/12/16
Apolloscientific
Product number
PC1397
Product name
2-Bromo-4-fluoroaniline
Purity
99%
Packaging
100g
Price
$48
Updated
2021/12/16
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2-Bromo-4-fluoroaniline Chemical Properties,Usage,Production

Uses

2-Bromo-4-fluoroaniline is an organic compound that is an aniline derivative. It is mainly used as an organic synthesis reagent in experimental research.

Chemical Properties

Clear yellow-brown liquid

General Description

2-Bromo-4-fluoroaniline is an aryl fluorinated building block.

Synthesis

371-40-4

1003-98-1

The general procedure for the synthesis of 2-bromo-4-fluoroaniline from 4-fluoroaniline was as follows: 200 mL of distilled N,N-dimethylformamide (DMF) and 4-fluoroaniline (8.64 mL, 58.13 mmol) were added to a two-necked flask equipped with a stirring device. N-bromosuccinimide (11.4 g, 63.95 mmol) dissolved in DMF was added slowly and dropwise with stirring. After completion of the reaction, extraction was carried out using dichloromethane (CH2Cl2). The product was purified by column chromatography (eluent ratio of ethyl acetate: n-hexane = 1:4), and the target product 2-bromo-4-fluoroaniline was finally obtained in 95% yield.

References

[1] Patent: KR2018/50795, 2018, A. Location in patent: Paragraph 0134; 0135; 0152-0154
[2] Tetrahedron Letters, 2000, vol. 41, # 13, p. 2083 - 2085
[3] Journal of the American Chemical Society, 2011, vol. 133, # 18, p. 6868 - 6870
[4] Chemistry - A European Journal, 2011, vol. 17, # 49, p. 13665 - 13669
[5] Tetrahedron Letters, 2014, vol. 55, # 38, p. 5338 - 5341

2-Bromo-4-fluoroaniline Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Bromo-4-fluoroaniline Suppliers

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View Lastest Price from 2-Bromo-4-fluoroaniline manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
2-Bromo-4-fluoroaniline 1003-98-1
Price
US $40.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-09-07
Hebei Chuanghai Biotechnology Co,.LTD
Product
2-Bromo-4-fluoroaniline 1003-98-1
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-19
Zhejiang Kinso Technology Co., LTD.
Product
2-Bromo-4-fluoroaniline 1003-98-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000KG
Release date
2024-07-12

1003-98-1, 2-Bromo-4-fluoroanilineRelated Search:

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  • C2 to C6
  • Amines
  • Building Blocks
  • Organic Building Blocks
  • Nitrogen Compounds
  • amine| alkyl Fluorine| alkyl bromide
  • Pyridines
  • Miscellaneous
  • Anilines, Amides & Amines
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  • C2 to C6
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  • 1003-98-1