2-BROMO-5-CHLOROANILINE

Product Name: 2-BROMO-5-CHLOROANILINE
CAS No.: 823-57-4
Chemical Name: 2-BROMO-5-CHLOROANILINE
Synonyms: Bromo-5-chloroaniline;2-BROMO-5-CHLOROANILINE;2-BROMO-5-CHLOROBENZENAMINE;2-Bromo-5-chloroaniline 97%;2-Bromo-5-chloroaniline >BenzenaMine,2-broMo-5-chloro-;2-BroMo-5-chloroaniline , 95.0%(GC&T;2-BROMO-5-CHLOROANILINE ISO 9001：2015 REACH
CBNumber: CB6714501
Molecular Formula: C6H5BrClN
Formula Weight: 206.47
MOL File: 823-57-4.mol

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2-BROMO-5-CHLOROANILINE Property

Melting point:: 38 °C
Boiling point:: 128 °C / 7mmHg
Density: 1.722±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: soluble in Methanol
form: powder to lump
pka: 1.48±0.10(Predicted)
color: White to Brown
InChI: InChI=1S/C6H5BrClN/c7-5-2-1-4(8)3-6(5)9/h1-3H,9H2
InChIKey: NLEZSQHAFMZAGU-UHFFFAOYSA-N
SMILES: C1(N)=CC(Cl)=CC=C1Br

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Safety

Hazard Codes: Xi
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36/37/39
Hazard Note: Irritant
HS Code: 29214200

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: B3182
Product name: 2-Bromo-5-chloroaniline
Purity: >97.0%(GC)(T)
Packaging: 1g
Price: $16
Updated: 2025/07/31

TCI Chemical

Product number: B3182
Product name: 2-Bromo-5-chloroaniline
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $47
Updated: 2025/07/31

TCI Chemical

Product number: B3182
Product name: 2-Bromo-5-chloroaniline
Purity: >97.0%(GC)(T)
Packaging: 25g
Price: $140
Updated: 2025/07/31

TRC

Product number: B699448
Product name: 2-Bromo-5-chloroaniline
Packaging: 50mg
Price: $45
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3630-D-X6
Product name: 2-Bromo-5-chloroaniline
Purity: 97.0%
Packaging: 5G
Price: $16
Updated: 2021/12/16

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2-BROMO-5-CHLOROANILINE Chemical Properties,Usage,Production

Chemical Properties

Brown solid

Synthesis

41513-04-6

823-57-4

General procedure for the synthesis of 2-bromo-5-chloroaniline from 2-bromo-5-chloronitrobenzene: 1-bromo-4-chloro-2-nitrobenzene (140 g, 0.59 mol) was dissolved in 2.5 L of methanol and heated gently in a hot water bath at 50 °C. A solution of ammonium formate (303 g, 4.81 mol) in 500 mL of water was added slowly. Zinc powder (155 g, 2.36 mol) was carefully added in batches, taking care to control the exothermic and reflux rate of the reaction. The addition of zinc powder needs to be done carefully to avoid excess unreacted zinc residue. After completion of the reaction, it was cooled to room temperature and filtered through a pad of diatomaceous earth (Celite). The filtrate was concentrated under reduced pressure until a two-phase mixture of red oil and water appeared. The product was extracted with diethyl ether (5 × 200 mL). The organic phases were combined, dried with anhydrous sodium sulfate, decanted and concentrated under reduced pressure to give a reddish brown oil. The oil was redissolved in 150 mL of mixed dichloromethane/hexane solvent and filtered through a short column of silica gel. The filtrate was concentrated under reduced pressure to give an orange colored oil. Hexane (200 mL) was added and cooled in a dry ice bath to precipitate 2-bromo-5-chloroaniline as a light yellow solid (92.1 g, 75% yield), which was collected by vacuum filtration.

References

[1] Patent: US2005/192310, 2005, A1. Location in patent: Page/Page column 22-23
[2] Patent: US2017/158704, 2017, A1. Location in patent: Paragraph 0678; 0679
[3] Farmaco, 2003, vol. 58, # 9, p. 723 - 738
[4] European Journal of Organic Chemistry, 2018, vol. 2018, # 26, p. 3416 - 3425
[5] Angewandte Chemie - International Edition, 2008, vol. 47, # 5, p. 888 - 890

2-BROMO-5-CHLOROANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-BROMO-5-CHLOROANILINE Suppliers

Americas 1 Canada 1 China 188 Europe 1 France 1 Germany 2 India 3 Japan 1 United Kingdom 4 United States 8 Global 210

Nantong Haochun Biotechnology Co., Ltd

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Energy Chemical

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View Lastest Price from 2-BROMO-5-CHLOROANILINE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-BROMO-5-CHLOROANILINE 823-57-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-05-20

Henan Fengda Chemical Co., Ltd

Product: 2-Bromo-5-chloroaniline 823-57-4
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%, 99.5% Sublimated
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-31

Career Henan Chemical Co

Product: 2-BROMO-5-CHLOROANILINE 823-57-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 500KG
Release date: 2018-08-19

823-57-4, 2-BROMO-5-CHLOROANILINERelated Search:

4,6-DIBROMO-2,3-DICHLOROANILINE 3-CHLORO-2,6-DIBROMO-4-FLUOROANILINE 3-CHLORO-2,6-DIBROMO-4-METHYLANILINE 2-AMINO-3,5-DIBROMO-6-CHLOROBENZOIC ACID 2-BROMO-5-CHLOROANILINE 1-Bromo-4,5-dichloro-2-nitrobenzene 2-BROMO-5-CHLORO-4-METHYL-ANILINE 2-Bromo-5-chloronitrobenzene 2-Bromo-4-chloroaniline 99%,DISCONTINUED !2-Bromo-4-chloroaniline,2-BROMO-4-CHLOROANILINE,2-Bromo-4-chloroaniline,98% 2,6-Dibromo-4-chloroaniline 4-BROMO-2-CHLOROANILINE,4-BROMO-2-CHLOROANILINE, 98+%,4-Bromo-2-chloroaniline 98% 4-BROMO-3-CHLOROANILINE PESTANAL, 250 MG,4-BROMO-3-CHLOROANILINE,4-BROMO-3-CHLOROANILINE 98+% 5-BROMO-2-CHLOROANILINE,3-BROMO-6-CHLOROANILINE 3-Bromo-5-chloroaniline 5-BROMO-4'-CHLOROSALICYLANILIDE 3-bromo-2-chloroaniline (N,N-Bis-t-Boc)-5-bromo-2-chloroaniline 3-Chloro-2,6-dibromo-4-methylphenylisothiocyanate

2-Bromo-5-chloroaniline 97%

2-BROMO-5-CHLOROBENZENAMINE

2-BROMO-5-CHLOROANILINE

BenzenaMine,2-broMo-5-chloro-

2-BroMo-5-chloroaniline , 95.0%(GC&T

Bromo-5-chloroaniline

2-Bromo-5-chloroaniline &gt

2-BROMO-5-CHLOROANILINE ISO 9001：2015 REACH

823-57-4

823-54-7

Anilines, Amides & Amines

Bromine Compounds

Chlorine Compounds