4-Bromo-2-chloroaniline
- Product Name
- 4-Bromo-2-chloroaniline
- CAS No.
- 38762-41-3
- Chemical Name
- 4-Bromo-2-chloroaniline
- Synonyms
- Benzenamine, 4-bromo-2-chloro-;4-Bromo-2-chloroanil;-Bromo-2-chloroaniline;4-BROMO-2-CHLOROANILINE;4-Bromo-2-chloroanilinev;4-Bromo-2-chloroaniline >4-Bromo-2-chloroaniline 98%;4-Bromo-2-chloroaniline,99%;4-Bromo-2-chloro-phenylamine;4-BROMO-2-CHLOROANILINE, 98+%
- CBNumber
- CB7218516
- Molecular Formula
- C6H5BrClN
- Formula Weight
- 206.47
- MOL File
- 38762-41-3.mol
4-Bromo-2-chloroaniline Property
- Melting point:
- 70-72 °C (lit.)
- Boiling point:
- 241.8±20.0 °C(Predicted)
- Density
- 1.6567 (rough estimate)
- refractive index
- 1.5400 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 1.95±0.10(Predicted)
- form
- Crystalline Powder
- color
- Slightly yellow to light brown
- BRN
- 3117740
- InChI
- InChI=1S/C6H5BrClN/c7-4-1-2-6(9)5(8)3-4/h1-3H,9H2
- InChIKey
- INMZDDDQLHKGPF-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(Br)C=C1Cl
- CAS DataBase Reference
- 38762-41-3(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,T,Xi
- Risk Statements
- 20/21/22-20/21
- Safety Statements
- 36-23
- WGK Germany
- 3
- Hazard Note
- Toxic
- HazardClass
- IRRITANT
- HS Code
- 29214200
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P309IF exposed or if you feel unwell:
P310Immediately call a POISON CENTER or doctor/physician.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B1993
- Product name
- 4-Bromo-2-chloroaniline
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $39
- Updated
- 2025/07/31
- Product number
- B1993
- Product name
- 4-Bromo-2-chloroaniline
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $130
- Updated
- 2025/07/31
- Product number
- B699468
- Product name
- 4-Bromo-2-chloroaniline
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR0849
- Product name
- 4-Bromo-2-chloroaniline
- Purity
- 98%
- Packaging
- 25g
- Price
- $22
- Updated
- 2021/12/16
- Product number
- 3630-D-X8
- Product name
- 4-Bromo-2-chloroaniline
- Purity
- 98.0%
- Packaging
- 25g
- Price
- $24
- Updated
- 2021/12/16
4-Bromo-2-chloroaniline Chemical Properties,Usage,Production
Chemical Properties
SLIGHTLY YELLOW TO LIGHT BROWN CRYSTALLINE POWDER
Uses
4-Bromo-2-chloroaniline was used in the peparation of 3,4-dichloro-α-trichloromethylbenzyl alcohol.
Synthesis
95-51-2
38762-41-3
The general procedure for the synthesis of 4-bromo-2-chloroaniline from o-chloroaniline was as follows: 254 mg (2 mmol) of o-chloroaniline and 143 mg (1.2 mmol) of potassium bromide were dissolved in 10 mL of a solvent mixture of acetic acid (AcOH) and water (9:1, v/v), and the solution was subsequently transferred to a 50 mL three-neck flask. The reaction temperature was controlled by magnetic stirring at 25°C for 1 h in a thermostatic water bath with continuous stirring. Within the first 15 min of the start of the reaction, 1.8 g (1.8 mmol) of ZnAl-BrO3-LDHs was slowly added.After completion of the reaction, the reaction mixture was extracted with dichloromethane (2 × 10 mL) and the organic phases were combined. Two silica gels (200-300 mesh) were added to the combined organic phases, and the dichloromethane was subsequently removed by distillation under reduced pressure. Finally, purification was carried out using column chromatography (eluent was a solvent mixture of petroleum ether and ethyl acetate in a 10:1 ratio, v/v) to give 321 mg of gray solid product in 78% yield.
References
[1] Tetrahedron Letters, 2005, vol. 46, # 51, p. 8959 - 8963
[2] Russian Journal of Applied Chemistry, 2009, vol. 82, # 9, p. 1570 - 1576
[3] Chinese Chemical Letters, 2012, vol. 23, # 4, p. 387 - 390
[4] Monatshefte fur Chemie, 2013, vol. 144, # 2, p. 179 - 181
[5] Journal of the Iranian Chemical Society, 2012, vol. 9, # 3, p. 321 - 326
4-Bromo-2-chloroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Bromo-2-chloroaniline manufacturers
- Product
- 4-bromo-2-chloroaniline 38762-41-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1
- Release date
- 2025-08-28
- Product
- 4-Bromo-2-chloroaniline 38762-41-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-26
- Product
- 4-Bromo-2-chloroaniline 38762-41-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-13