Faropenem sodium hemipentahydrate
- Product Name
- Faropenem sodium hemipentahydrate
- CAS No.
- 106560-14-9
- Chemical Name
- Faropenem sodium hemipentahydrate
- Synonyms
- FROPENEM;FAROPENEM;Faropenem sodium hemi 5-hydrate;Faropenem sodium hemipentahydrate;Faropenem sodium hemipentahydrate USP/EP/BP;6α-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid;(5R,6S,8R,2'R)-2-(2'-tetrahydrofuryl)-6-(1-hydroxyethyl)-2-penem-3-carboxylic acid;6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid;(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-2-oxolanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
- CBNumber
- CB1300660
- Molecular Formula
- C12H15NO5S
- Formula Weight
- 285.32
- MOL File
- 106560-14-9.mol
Faropenem sodium hemipentahydrate Property
- Boiling point:
- 570.2±50.0 °C(Predicted)
- Density
- 1.56±0.1 g/cm3(Predicted)
- pka
- 4.00±0.40(Predicted)
- CAS DataBase Reference
- 106560-14-9
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F103303
- Product name
- Faropenem
- Packaging
- 100mg
- Price
- $580
- Updated
- 2021/12/16
- Product number
- API0002771
- Product name
- FROPENEM
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $927.76
- Updated
- 2021/12/16
- Product number
- API-1035
- Product name
- Fropenem
- Purity
- 98%
- Packaging
- 100mg
- Price
- $600
- Updated
- 2021/12/16
- Product number
- 1723A
- Product name
- Faropenem
- Packaging
- 10mg
- Price
- $39
- Updated
- 2021/12/16
- Product number
- 1723A
- Product name
- Faropenem
- Packaging
- 100mg
- Price
- $89
- Updated
- 2021/12/16
Faropenem sodium hemipentahydrate Chemical Properties,Usage,Production
Description
Farom was launched in Japan for use as an antibiotic against common respiratory tract pathogens. It can be prepared by several related routes of about seven steps starting with tetrahydrofuran-2-thiocarboxylic acid and a silylated azetidinone. It is a broad spectrum oral penem antibiotic that is β-lactamase stable. Farom is the most active β-lactam against anaerobes (more than cefaclor, cefixime and amoxicillin) but also has activity against Gram-positive, Gram-negative and enterobacteriaceae. It is equally active against strains carrying plasmid and chromosome mediated β-lactamases. The short plasma elimination half-life is the result of hydrolysis by renal dehydropeptidase. It is more stable to hydrolysis by extended spectrum β-lactamases than some second and third generation cephalosporins.
Originator
Suntory (Japan)
Uses
Faropenem (cas# 106560-14-9) is a compound useful in organic synthesis.
Uses
Treatmentof bacterial infections.
Definition
ChEBI: 6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid is a faropenem. It is a conjugate acid of a 6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylate.
brand name
Farom
Antimicrobial activity
An orally active penem with a broad spectrum of antibacterial activity, including activity against selected anaerobic pathogens. Although it is active against most enterobacteria, it has reduced activity against Ser. marcescens, Enterobacter spp. and some Providencia spp. It generally retains activity against many Gram-positive organisms, but has no useful activity against Ps. aeruginosa. It has reduced activity against E. faecium, methicillin-resistant Staph. aureus (MRSA) and some strains of coagulase-negative staphylococci. It is stable to hydrolysis by extended spectrum β-lactamases, but is hydrolyzed by carbapenemases. Esterified prodrugs with increased bioavailability have been studied in clinical trials but have not received regulatory approval.
Faropenem sodium hemipentahydrate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Faropenem sodium hemipentahydrate manufacturers
- Product
- Faropenem sodium hemipentahydrate 106560-14-9
- Price
- US $7.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-17