Faropenem sodium hemipentahydrate

Product Name: Faropenem sodium hemipentahydrate
CAS No.: 106560-14-9
Chemical Name: Faropenem sodium hemipentahydrate
Synonyms: FROPENEM;FAROPENEM;Faropenem Sodium Impurity G;Faropenem sodium hemi 5-hydrate;Faropenem sodium hemipentahydrate;Faropenem sodium hemipentahydrate USP/EP/BP;6α-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid;(5R,6S,8R,2'R)-2-(2'-tetrahydrofuryl)-6-(1-hydroxyethyl)-2-penem-3-carboxylic acid;6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid;(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-2-oxolanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
CBNumber: CB1300660
Molecular Formula: C12H15NO5S
Formula Weight: 285.32
MOL File: 106560-14-9.mol

More

Less

Faropenem sodium hemipentahydrate Property

Boiling point:: 570.2±50.0 °C(Predicted)
Density: 1.56±0.1 g/cm3(Predicted)
pka: 4.00±0.40(Predicted)
CAS DataBase Reference: 106560-14-9

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: F103303
Product name: Faropenem
Packaging: 100mg
Price: $580
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0002771
Product name: FROPENEM
Purity: 95.00%
Packaging: 5G
Price: $927.76
Updated: 2021/12/16

AHH

Product number: API-1035
Product name: Fropenem
Purity: 98%
Packaging: 100mg
Price: $600
Updated: 2021/12/16

AvaChem

Product number: 1723A
Product name: Faropenem
Packaging: 10mg
Price: $39
Updated: 2021/12/16

AvaChem

Product number: 1723A
Product name: Faropenem
Packaging: 100mg
Price: $89
Updated: 2021/12/16

More

Less

Faropenem sodium hemipentahydrate Chemical Properties,Usage,Production

Description

Farom was launched in Japan for use as an antibiotic against common respiratory tract pathogens. It can be prepared by several related routes of about seven steps starting with tetrahydrofuran-2-thiocarboxylic acid and a silylated azetidinone. It is a broad spectrum oral penem antibiotic that is β-lactamase stable. Farom is the most active β-lactam against anaerobes (more than cefaclor, cefixime and amoxicillin) but also has activity against Gram-positive, Gram-negative and enterobacteriaceae. It is equally active against strains carrying plasmid and chromosome mediated β-lactamases. The short plasma elimination half-life is the result of hydrolysis by renal dehydropeptidase. It is more stable to hydrolysis by extended spectrum β-lactamases than some second and third generation cephalosporins.

Originator

Suntory (Japan)

Uses

Faropenem (cas# 106560-14-9) is a compound useful in organic synthesis.

Uses

Treatmentof bacterial infections.

Definition

ChEBI: 6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid is a faropenem. It is a conjugate acid of a 6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylate.

brand name

Farom

Antimicrobial activity

An orally active penem with a broad spectrum of antibacterial activity, including activity against selected anaerobic pathogens. Although it is active against most enterobacteria, it has reduced activity against Ser. marcescens, Enterobacter spp. and some Providencia spp. It generally retains activity against many Gram-positive organisms, but has no useful activity against Ps. aeruginosa. It has reduced activity against E. faecium, methicillin-resistant Staph. aureus (MRSA) and some strains of coagulase-negative staphylococci. It is stable to hydrolysis by extended spectrum β-lactamases, but is hydrolyzed by carbapenemases. Esterified prodrugs with increased bioavailability have been studied in clinical trials but have not received regulatory approval.

Faropenem sodium hemipentahydrate Preparation Products And Raw materials

Raw materials

TRIPHENYLMETHYL MERCAPTAN Triethyl phosphate Silver nitrate N,N-Diisopropylethylamine Tetrabutylammonium periodate Oxalyl chloride Chloromethane

Preparation Products

More

Less

Faropenem sodium hemipentahydrate Suppliers

China 102 Europe 2 Germany 1 India 4 United Kingdom 6 United States 20 Global 135

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

HBCChem, Inc.

Tel: +1-510-219-6317
Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
ProdList: 10648
Advantage: 60

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

CarboMer, Inc.

Tel: --
Fax: --
Email: sales@carbomer.com
Country: United States
ProdList: 4026
Advantage: 67

HBCChem Inc.

Tel: --
Fax: --
Email: sales@hbcchem-inc.com
Country: United States
ProdList: 4569
Advantage: 30

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6962
Advantage: 56

Beta Pharma, Inc.

Tel: --
Fax: --
Email: sales@betapharma.com
Country: United States
ProdList: 6226
Advantage: 60

ACIC Fine Chemicals Inc.

Tel: --
Fax: --
Email: sales@acic.com
Country: United States
ProdList: 492
Advantage: 48

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

2A PharmaChem USA

Tel: --
Fax: --
Email: sales@2apharmachem.com
Country: United States
ProdList: 6137
Advantage: 39

Altan Corporation

Tel: --
Fax: --
Email: OrderingService@AltanBiochemicals.com
Country: United States
ProdList: 1161
Advantage: 30

HONEST JOY HOLDINGS LIMITED

Tel: --
Fax: --
Email: sales@honestjoy.cn
Country: United States
ProdList: 6675
Advantage: 54

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

American Custom Chemicals Corporation

Tel: --
Fax: --
Email: sales@acccorporation.com
Country: United States
ProdList: 6820
Advantage: 51

BOSCHE SCIENTIFIC, LLC

Tel: --
Fax: --
Email: Sales@BoscheSci.com
Country: United States
ProdList: 6477
Advantage: 55

Fine Chem Trading LTD

Tel: --
Fax: --
Email: chemfinder@chemfinder.co.uk
Country: United States
ProdList: 1609
Advantage: 64

More

Less

View Lastest Price from Faropenem sodium hemipentahydrate manufacturers

Career Henan Chemical Co

Product: Faropenem sodium hemipentahydrate 106560-14-9
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100KG
Release date: 2018-12-17

106560-14-9, Faropenem sodium hemipentahydrateRelated Search:

Sodium bicarbonate Furazolidone Diclofenac sodium 5-Chlorovaleric acid Tetrahydrofuran Sodium hydroxide Sodium citrate Diphenolic acid Sodium acetate Sodium benzoate DL-α-Tocopherol Sodium chlorite Pralmorelin 2-(METHYLSULFONYL)ETHANOL Sodium chloride Sodium sulfate Ethyl maltol Sodium percarbonate

(+)-(5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

(5R,6S,8R,2'R)-2-(2'-tetrahydrofuryl)-6-(1-hydroxyethyl)-2-penem-3-carboxylic acid

4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-, [5R-[3(R*),5α,6α(R*)]]-

4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-, (5R,6S)-

6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monosodium salt hemipentahydrate

Faropenem sodium hemipentahydrate

FAROPENEM

FROPENEM

[5R-[3(R^<*>^)，5α，6α(R^<*>^)]]-6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-4-thia-1-azobicyclo[3.2.0]leapt-2- ene-2-carboxylicacid

(5R,6R)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-2-oxolanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-keto-3-[(2R)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid

6α-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid

Faropenem sodium hemipentahydrate USP/EP/BP

(5R,6S)-6-((R)-1-Hydroxyethyl)-7-oxo-3-((R)-tetrahydrofuran-2-yl)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Faropenem-d5Q: What is Faropenem-d5 Q: What is the CAS Number of Faropenem-d5 Q: What are the applications of Faropenem-d5

Faropenem sodium hemi 5-hydrate

Faropenem Sodium Impurity G

106560-14-9

22547-49-3

2C12H14NNaO5S5H20

2C12H14NO5S2Na5H2O

API