2-FLUORO-6-METHOXYANILINE

Product Name: 2-FLUORO-6-METHOXYANILINE
CAS No.: 446-61-7
Chemical Name: 2-FLUORO-6-METHOXYANILINE
Synonyms: -FLUORO-6-METHOXYANILINE;2-FLUORO-6-METHOXYANILINE;2-fluoro-6-methoxybenzenamine;2-Fluoro-6-methoxy-phenylamine;Benzenamine, 2-fluoro-6-methoxy-;2-Amino-3-fluoroanisole, 6-Fluoro-o-anisidine;2-AMino-3-fluoroanisole[2-Fluoro-6-Methoxyaniline]
CBNumber: CB1302174
Molecular Formula: C7H8FNO
Formula Weight: 141.14
MOL File: 446-61-7.mol

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2-FLUORO-6-METHOXYANILINE Property

Boiling point:: 208 °C(Press: 756 Torr)
Density: 1.176±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 3.15±0.10(Predicted)
form: slightly viscous liquid
color: Clear, peach/khaki
InChI: InChI=1S/C7H8FNO/c1-10-6-4-2-3-5(8)7(6)9/h2-4H,9H2,1H3
InChIKey: VHHKZASLPJMWJI-UHFFFAOYSA-N
SMILES: C1(N)=C(OC)C=CC=C1F

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22
Hazard Note: Irritant
HS Code: 2922290090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: F592235
Product name: 2-Fluoro-6-methoxyaniline
Packaging: 250mg
Price: $65
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4656-3-66
Product name: 2-Fluoro-6-methoxyaniline
Purity: 97%
Packaging: 250mg
Price: $69
Updated: 2021/12/16

Matrix Scientific

Product number: 089702
Product name: 2-Fluoro-6-methoxyaniline
Purity: 95+%
Packaging: 1g
Price: $42
Updated: 2021/12/16

Apolloscientific

Product number: PC0872
Product name: 2-Fluoro-6-methoxyaniline
Packaging: 250mg
Price: $51
Updated: 2021/12/16

Apolloscientific

Product number: PC0872
Product name: 2-Fluoro-6-methoxyaniline
Packaging: 1g
Price: $61
Updated: 2021/12/16

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2-FLUORO-6-METHOXYANILINE Chemical Properties,Usage,Production

Chemical Properties

black liquid

Synthesis

641-49-6

446-61-7

General procedure for the synthesis of 2-fluoro-6-methoxyaniline using 3-fluoro-2-nitroanisole as starting material: 10% Pd/C catalyst (7.46 g, 70.1 mmol) and ethanol (400 mL) were added to a Parr reactor followed by 1-fluoro-3-methoxy-2-nitrobenzene (40.0 g, 234 mmol). The reactor was evacuated and filled with hydrogen (50 psi) and the reaction was shaken for 5 h under hydrogen atmosphere. After completion of the reaction, the catalyst was removed by Celite filtration and the filtrate was concentrated to give 2-fluoro-6-methoxyaniline (30.0 g, 83% yield) as a colorless oil. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 3.75 (broad single peak, 2H), 3.86 (single peak, 3H), 6.58-6.71 (multiple peaks, 3H); the molecular ion peak [M + H]+ = 142 was detected by LC-MS (LC-ES).

References

[1] Patent: WO2018/69863, 2018, A1. Location in patent: Page/Page column 248
[2] Journal of the American Chemical Society, 1932, vol. 54, p. 2973,2976
[3] Journal of the Chemical Society, 1931, p. 981
[4] Journal of Medicinal Chemistry, 1993, vol. 36, # 11, p. 1641 - 1653

2-FLUORO-6-METHOXYANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-FLUORO-6-METHOXYANILINE Suppliers

Canada 1 China 113 India 2 Italy 1 Ukraine 1 United Kingdom 4 United States 16 Global 138

Shanghai Scochem Technology Co., Ltd.

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Zhenjiang Carbochem Pharmatech Co.,LTD

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Shanghai Chemilab Biotechnology CO.,Ltd

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J & K SCIENTIFIC LTD.

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Energy Chemical

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Capot Chemical Co., Ltd

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JinYan Chemicals(ShangHai) Co.,Ltd.

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Adamas Reagent, Ltd.

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Shanghai Harvest Chemical Industrial Co., Ltd.

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Nanjing Chemlin Chemical Co., Ltd

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View Lastest Price from 2-FLUORO-6-METHOXYANILINE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2-FLUORO-6-METHOXYANILINE 446-61-7
Price: US $1.00-28.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20000KG
Release date: 2024-07-29

Career Henan Chemical Co

Product: 2-FLUORO-6-METHOXYANILINE 446-61-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-26

446-61-7, 2-FLUORO-6-METHOXYANILINERelated Search:

4-FLUORO-3-METHOXYANILINE,2-fluoro-5-aminoanisole(4-fluoro-3-methoxyaniline) 3-Fluoro-4-Methoxyaniline 2-Fluoro-4-Aminoanisole,3-FLUORO-4-METHOXYANILINE,3-Fluoro-4-methoxyaniline, 98+% 4-FLUORO-3-METHOXYANILINE HYDROCHLORIDE 4-Fluoro-2-methoxyaniline hydrochloride,4-Fluoro-2-methoxyaniline, HCl,4-Fluoro-2-methoxyaniline hydrochloride 98% 2-FLUORO-4-METHOXYANILINE 3-FLUORO-2-METHOXYANILINE 4-FLUORO-2-METHOXYANILINE 3-BROMO-5-FLUORO-4-METHOXYANILINE,3-Bromo-5-fluoro-4-methoxyaniline 98%,3-Bromo-5-fluoro-4-methoxyaniline98% 5-Fluoro-2-methoxyaniline hydrochloride N-Methyl 4-fluoro-2-methoxyaniline 2-FLUORO-4-METHOXYANILINE HYDROCHLORIDE,2-FLUORO-4-METHOXYANILINE, HCL 2-CHLORO-6-FLUORO-3-METHOXYANILINE 2-Bromo-4-fluoro-5-methoxyaniline 2-fluoro-5-methoxyaniline 3-FLUORO-4-METHOXYANILINE HYDROCHLORIDE 3-FLUORO-5-METHOXYANILINE 5-FLUORO-2-METHOXYANILINE 3-Fluoro-6-Methoxyaniline

2-FLUORO-6-METHOXYANILINE

2-fluoro-6-methoxybenzenamine

2-Amino-3-fluoroanisole, 6-Fluoro-o-anisidine

2-AMino-3-fluoroanisole[2-Fluoro-6-Methoxyaniline]

2-Fluoro-6-methoxy-phenylamine

-FLUORO-6-METHOXYANILINE

Benzenamine, 2-fluoro-6-methoxy-

446-61-7