Bromo-PEG2-acid
- Product Name
- Bromo-PEG2-acid
- CAS No.
- 1807503-92-9
- Chemical Name
- Bromo-PEG2-acid
- Synonyms
- Br-PEG2-acid;Bromo-PEG3-acid;Bromo-PEG2-acid;CAS_1807503-92-9;Bromo-PEG2-C2-acid;Br-PEG2-CH2CH2COOH;Bromo-PEG2-acid >=95%;Bromo-PEG2-propionic acid;3-(2-(2-Bromoethoxy)ethoxy)propanoic acid;Propanoic acid, 3-[2-(2-bromoethoxy)ethoxy]-
- CBNumber
- CB13048712
- Molecular Formula
- C7H13BrO4
- Formula Weight
- 241.08
- MOL File
- 1807503-92-9.mol
Bromo-PEG2-acid Property
- Boiling point:
- 347.2±27.0 °C(Predicted)
- Density
- 1.464±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- pka
- 4.27±0.10(Predicted)
Safety
- HS Code
- 2918999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 901572
- Product name
- Bromo-PEG2-acid
- Purity
- ≥95%
- Packaging
- 50MG
- Price
- $139
- Updated
- 2023/06/20
- Product number
- 0328DY
- Product name
- 3-(2-(2-Bromoethoxy)ethoxy)propanoicacid
- Packaging
- 50mg
- Price
- $151
- Updated
- 2021/12/16
- Product number
- BP-22246
- Product name
- Bromo-PEG2-acid
- Purity
- 98%
- Packaging
- 100mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- 0328DY
- Product name
- 3-(2-(2-Bromoethoxy)ethoxy)propanoicacid
- Packaging
- 250mg
- Price
- $387
- Updated
- 2021/12/16
- Product number
- POL0002413
- Product name
- BROMO-PEG3-ACID
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $393.75
- Updated
- 2021/12/16
Bromo-PEG2-acid Chemical Properties,Usage,Production
Description
Bromo-PEG2-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Bromo-PEG2-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG2-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
Bromo-PEG2-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Bromo-PEG2-acid Suppliers
View Lastest Price from Bromo-PEG2-acid manufacturers
- Product
- Br-PEG2-acid 1807503-92-9
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-25
- Product
- Bromo-PEG2-acid 1807503-92-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 500kg
- Release date
- 2018-08-19