5-Bromo-6-chloronicotinic acid
- Product Name
- 5-Bromo-6-chloronicotinic acid
- CAS No.
- 29241-62-1
- Chemical Name
- 5-Bromo-6-chloronicotinic acid
- Synonyms
- 5-Bromo-6-Chloro Niacin;5-BROMO-6-CHLORONICOTINIC ACID;5-Bromo-6-chloronicotinicAcid>5-Bromo-6-chloronicotinic acid 97%;5-Bromo-6-chloronicotinic acid ,97%;5-Bromo-6-chloronicotinic acidCHLORIDE;5-bromo-6-chloropyridine-3-carboxylate;5-Bromo-6-chloronicotinic ac+D33:D37id;5-bromo-6-chloropyridine-3-carboxylicaci;5-Bromo-6-chloro-3-pyridinecarboxylicacid
- CBNumber
- CB1312304
- Molecular Formula
- C6H3BrClNO2
- Formula Weight
- 236.45
- MOL File
- 29241-62-1.mol
5-Bromo-6-chloronicotinic acid Property
- Melting point:
- 166-168°C
- Boiling point:
- 370.0±42.0 °C(Predicted)
- Density
- 1.917±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 2.85±0.10(Predicted)
- color
- White to Light yellow
- InChI
- InChI=1S/C6H3BrClNO2/c7-4-1-3(6(10)11)2-9-5(4)8/h1-2H,(H,10,11)
- InChIKey
- DXEUARPQHJXMII-UHFFFAOYSA-N
- SMILES
- C1=NC(Cl)=C(Br)C=C1C(O)=O
- CAS DataBase Reference
- 29241-62-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36/37/38
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B4355
- Product name
- 5-Bromo-6-chloronicotinic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $35
- Updated
- 2025/07/31
- Product number
- B4355
- Product name
- 5-Bromo-6-chloronicotinic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $104
- Updated
- 2025/07/31
- Product number
- B684113
- Product name
- 5-Bromo-6-chloronicotinic Acid
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B684113
- Product name
- 5-Bromo-6-chloronicotinic Acid
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 021370
- Product name
- 5-Bromo-6-chloronicotinic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $11
- Updated
- 2021/12/16
5-Bromo-6-chloronicotinic acid Chemical Properties,Usage,Production
Chemical Properties
White solid
Uses
5-Bromo-6-chloronicotinic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis
41668-13-7
29241-62-1
Synthesis of 5-bromo-6-chloronicotinic acid: 5-bromo-6-hydroxynicotinic acid (10 g, 45 mmol), tetramethylammonium chloride (5.4 g, 49 mmol), and phosphorus triclosan (20 mL) were sequentially added to a reaction flask, and the mixture was heated to reflux and held for 3 hours. Upon completion of the reaction, the reaction mixture was slowly poured into ice water and stirred continuously for 2 hours. The precipitated solid was collected by filtration, dissolved in ethyl acetate (300 mL) and dried by adding anhydrous sodium sulfate. The desiccant was removed by filtration and the filtrate was concentrated under reduced pressure to give 10.5 g (97% yield) of the target product 5-bromo-6-chloronicotinic acid as a pink solid. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 8.53 (d, J = 2.02 Hz, 1H), 8.85 (d, J = 2.02 Hz, 1H), 13.57 (s, 1H).
References
[1] Patent: WO2007/70818, 2007, A1. Location in patent: Page/Page column 103
[2] Journal of Medicinal Chemistry, 2005, vol. 48, # 15, p. 4892 - 4909
[3] Journal of Medicinal Chemistry, 2013, vol. 56, # 24, p. 9874 - 9896
5-Bromo-6-chloronicotinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Bromo-6-chloronicotinic acid manufacturers
- Product
- 5-Bromo-6-chloronicotinic acid? 29241-62-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1
- Release date
- 2025-08-28
- Product
- 5-Bromo-6-chloronicotinic acid 29241-62-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-04
- Product
- 5-Bromo-6-chloronicotinic acid 29241-62-1
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09