3-Bromo-2-chloropyridine

Product Name: 3-Bromo-2-chloropyridine
CAS No.: 52200-48-3
Chemical Name: 3-Bromo-2-chloropyridine
Synonyms: 2-CHLORO-3-BROMOPYRIDINE;3-Bromo-2-chL;TIMTEC-BB SBB003618;OTAVA-BB BB7110952626;-Bromo-2-chloropyridine;3-BROMO-2-CHLOROPYRIDINE;bromo-3 chloro-2 pyridine;3-Bromo-2-chlorolpyridine;Pyridine, 3-bromo-2-chloro-;5-Bromo-3-nitro-3-pyridinol
CBNumber: CB8375195
Molecular Formula: C5H3BrClN
Formula Weight: 192.44
MOL File: 52200-48-3.mol

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3-Bromo-2-chloropyridine Property

Melting point:: 54-57 °C (lit.)
Boiling point:: 97 °C / 10mmHg
Density: 1.7783 (rough estimate)
refractive index: 1.5400 (estimate)
storage temp.: Inert atmosphere,Room Temperature
pka: -0.63±0.10(Predicted)
form: Crystalline Powder, Crystals or Flakes or Solid
color: White to yellow
BRN: 109812
InChI: InChI=1S/C5H3BrClN/c6-4-2-1-3-8-5(4)7/h1-3H
InChIKey: HDYNIWBNWMFBDO-UHFFFAOYSA-N
SMILES: C1(Cl)=NC=CC=C1Br
CAS DataBase Reference: 52200-48-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39-36/37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 553751
Product name: 3-Bromo-2-chloropyridine
Purity: 98%
Packaging: 5g
Price: $22.24
Updated: 2025/07/31

Sigma-Aldrich

Product number: 553751
Product name: 3-Bromo-2-chloropyridine
Purity: 98%
Packaging: 25g
Price: $59.57
Updated: 2025/07/31

TCI Chemical

Product number: B2328
Product name: 3-Bromo-2-chloropyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $30
Updated: 2025/07/31

TCI Chemical

Product number: B2328
Product name: 3-Bromo-2-chloropyridine
Purity: >98.0%(GC)
Packaging: 25g
Price: $82
Updated: 2025/07/31

TRC

Product number: B682305
Product name: 3-Bromo-2-chloropyridine
Packaging: 250g
Price: $725
Updated: 2021/12/16

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3-Bromo-2-chloropyridine Chemical Properties,Usage,Production

Chemical Properties

yellow Long needles

Uses

3-Bromo-2-chloropyridine may be used to synthesize:

acetylenic dipyridone
3-ethynyl-2-(phenylmethoxy)-pyridine
nemertelline
ortho-chlorodiheteroarylamine4 or 2-chloro-N-(2,3,7-trimethylbenzo[b]thien-6-yl)pyridin-3-amine

General Description

3-Bromo-2-chloropyridine can be synthesized from 3-amino-2-chloropyridine or 2-chloro-3-pyridinamine.

Synthesis

6298-19-7

52200-48-3

Example 3 Synthesis of 3-bromo-2-chloropyridine (7): water (45 mL) and 48% hydrobromic acid (27 mL) were sequentially added to a reaction vial containing 3-amino-2-chloropyridine (6) (2.57 g, 20 mmol) at room temperature. Subsequently, 2,2,6,6-tetramethylpiperidine 1-yloxy (TEMPO) (0.31 g, 2 mmol) was added to the mixed solution and the reaction system was cooled to below 10 °C. A solution of sodium nitrite (4.14 g) dissolved in water (30 mL) was added slowly and dropwise. The reaction mixture was stirred at room temperature for about 2 h. After stirring, the reaction mixture was neutralized by adding a 10 mol/L aqueous sodium hydroxide solution (40 mL). The reaction mixture was extracted with toluene (300 mL in two portions) and the organic phases were combined and washed with 50 mL of water. The organic layer was concentrated under reduced pressure to remove the solvent to afford the target product 3-bromo-2-chloropyridine (7) (3.08 g, 80.1% yield).

References

[1] Patent: US2013/144061, 2013, A1. Location in patent: Paragraph 0229; 0230
[2] Journal of Organic Chemistry, 1995, vol. 60, # 5, p. 1408 - 1412

3-Bromo-2-chloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Bromo-2-chloropyridine Suppliers

Americas 1 Belgium 1 China 348 Europe 1 France 2 Germany 6 India 37 Japan 2 Jordan 1 Switzerland 2 The Netherlands 1 Ukraine 2 United Kingdom 17 United States 55 Global 476

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View Lastest Price from 3-Bromo-2-chloropyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 3-Bromo-2-chloropyridine 52200-48-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-29

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: 3-Bromo-2-chloropyridine 52200-48-3
Price: US $100.00/Kg/Bag
Min. Order: 1KG
Purity: 99%
Supply Ability: 1kg
Release date: 2021-09-13

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: 3-Bromo-2-chloropyridine 52200-48-3
Price: US $100.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2021-09-15

52200-48-3, 3-Bromo-2-chloropyridineRelated Search:

3-BROMO-2-CHLORO-4-IODOPYRIDINE 5-BROMO-6-CHLOROPYRIDINE-3-CARBOXYLIC ACID 2-Chloro-3-bromo-5-methylpyridine 3-Bromo-2,6-dichloropyridine 2-Chloro-3-bromo-5-nitropyridine 3-Bromo-2-chloropyridine 3-BROMO-2-CHLOROPYRIDINE-5-SULPHONYL CHLORIDE,3-BROMO-2-CHLOROPYRIDINE-5-SULFONYL CHLORIDE,5-BROMO-6-CHLOROPYRIDINE-3-SULFONYL CHLORIDE 5-AMINO-3-BROMO-2-CHLOROPYRIDINE 3-BROMO-2-CHLORO-4-PICOLINE Methyl 3-bromo-2-chloropyridine-5-carboxylate 3-BROMO-2-CHLORO-6-PICOLINE 2,5-DIBROMO-3-CHLOROPYRIDINE 3-BROMO-2,5-DICHLOROPYRIDINE 2,3-DIBROMO-6-CHLOROPYRIDINE 4-BROMO-3-CHLOROPYRIDINE 3-BROMO-2-CHLOROPYRIDINE-4-BORONIC ACID 2-AMINO-3-BROMO-5-CHLOROPYRIDINE 3,5-Dibromo-2-chloropyridine

3-Bromo-2-chlorolpyridine

3-BROMO-2-CHLOROPYRIDINE 98+%

bromo-3 chloro-2 pyridine

3-broMo -2-chlorine pyridine

2 - chloro - 3 - broMide pyridine

3-Bromo-2-chloropyridine 98%

OTAVA-BB BB7110952626

2-CHLORO-3-BROMOPYRIDINE

TIMTEC-BB SBB003618

3-BROMO-2-CHLOROPYRIDINE

3-Bromo-2-chloropyridine &gt

3-Bromo-2-chL

Pyridine, 3-bromo-2-chloro-

5-Bromo-3-nitro-3-pyridinol

3-Bromo-2-chloropyridine ISO 9001：2015 REACH

52200-48-3 ISO 9001：2015 REACH

-Bromo-2-chloropyridine

3-Bromo-2-chloropyridine, 95%

52200-48-3

C5H3ClBrN

Halopyridines

Bromopyridines

Chloropyridines

Heterocyclic Building Blocks

Halogenated Heterocycles

Pyridines

Building Blocks

compounds of pyridine

C5Heterocyclic Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Variety of halogenated heterocyclic series

Bromopyridines

Chloropyridines

Halopyridines

Boronic Acid

blocks

Bromides

Pyridines

Pyridine

Pyridines, Pyrimidines, Purines and Pteredines

Halides

Pyridine series

alkyl chloride| alkyl bromide

bc0001