ChemicalBook > CAS DataBase List > 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE

2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE

Uses

Product Name: 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE
CAS No.: 93118-03-7
Chemical Name: 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE
Synonyms: 2-Fluoro-4-hydroxybenzonitrile;TIMTEC-BB SBB003469;3-Chloro-6-fluoroacetophenone;2-Choro-3-(trifluoroMethyl)benzaldehyde;2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE;Benzaldehyde, 2-chloro-3-(trifluoromethyl)-;2-Chloro-3-(trifluoromethyl)benzaldehyde98%;2-Chloro-3-(trifluoromethyl)benzaldehyde 98%;2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE ISO 9001：2015 REACH
CBNumber: CB1314368
Molecular Formula: C8H4ClF3O
Formula Weight: 208.57
MOL File: 93118-03-7.mol

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2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE Property

Melting point:: 37-43 °C (lit.)
Boiling point:: 216.6±35.0 °C(Predicted)
Density: 1.423±0.06 g/cm3(Predicted)
Flash point:: >230 °F
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: Crystals or Powder
color: White to off-white
Sensitive: Air Sensitive
BRN: 3543607
CAS DataBase Reference: 93118-03-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29122900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 481912
Product name: 2-Chloro-3-(trifluoromethyl)benzaldehyde
Purity: 96%
Packaging: 1g
Price: $33
Updated: 2023/01/07

TRC

Product number: C596550
Product name: 2-Chloro-3-(trifluoromethyl)benzaldehyde
Packaging: 100mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC105432
Product name: 2-chloro-3-(trifluoromethyl)benzaldehyde
Packaging: 1g
Price: $90
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC105432
Product name: 2-chloro-3-(trifluoromethyl)benzaldehyde
Packaging: 2g
Price: $140
Updated: 2021/12/16

Oakwood

Product number: 007804
Product name: 2-Chloro-3-(trifluoromethyl)benzaldehyde
Packaging: 5g
Price: $66
Updated: 2021/12/16

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2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE Chemical Properties,Usage,Production

Uses

2-Chloro-3-(trifluoromethyl)benzaldehyde can be used as an organic synthesis intermediate, which can be prepared by reacting 2-trifluoromethyl-chlorobenzene with n-butyllithium. It can be used to prepare the pharmaceutical intermediate (2-chloro-3-trifluoromethylbenzyl)cyclopropylamine.

General Description

4-Chloro-3-(trifluoromethyl)benzaldehyde is a substituted benzaldehyde.

Synthesis

68-12-2

93118-03-7

The general procedure for the synthesis of 2-chloro-3-(trifluoromethyl)benzaldehyde from N,N-dimethylformamide was as follows: n-butyllithium (1.6 M hexane solution, 173 mL, 277 mmol) was added dropwise to the reaction system at -70 °C. Subsequently, a tetrahydrofuran (500 mL) solution of 2-trifluoromethylchlorobenzene (50.0 g, 277 mmol) was slowly added. The reaction temperature was maintained at -70°C and the reaction mixture was stirred for 2 hours. Then, a tetrahydrofuran (100 mL) solution of N,N-dimethylformamide (21.3 mL, 277 mmol) was added. The reaction mixture was gradually warmed to room temperature and stirred overnight. Upon completion of the reaction, the reaction was quenched by the addition of water (200 mL) and the mixture was extracted with ether (2 x 200 mL). The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to remove the solvent. The residue was purified by fast column chromatography (eluent: heptane/ethyl acetate=20:1) to afford the target product 2-chloro-3-(trifluoromethyl)benzaldehyde (37.4 g, 65% yield). Analyzed by liquid chromatography-mass spectrometry: retention time t R = 0.96 min.

References

[1] Patent: WO2006/21402, 2006, A1. Location in patent: Page/Page column 42

2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE Suppliers

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View Lastest Price from 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE 93118-03-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-12-04

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE 93118-03-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE 93118-03-7
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 200kg
Release date: 2018-12-17

93118-03-7, 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDERelated Search:

4-Chloro-3-(trifluoromethyl)benzaldehyde 3-CHLORO-5-(TRIFLUOROMETHYL)BENZALDEHYDE 4-AMINO-3-CHLORO-5-(TRIFLUOROMETHYL)BENZALDEHYDE 4,5-Dichloro-2-(trifluoromethyl)benzaldehyde 5-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE 2-Chloro-5-(trifluoromethyl)benzaldehyde98%,2-Chloro-5-(trifluoromethyl)benzaldehyde, 97+%,2-CHLORO-5-(TRIFLUOROMETHYL)BENZALDEHYDE 2,3-DICHLORO-6-(TRIFLUOROMETHYL)BENZALDEHYDE 4-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE 2,6-Dichloro-3-(trifluoromethyl)-benzoic acid 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE 2-CHLORO-3-(TRIFLUOROMETHYL)BENZOIC ACID 3-(Trifluoromethyl)benzaldehyde 3-CHLORO-4-(TRIFLUOROMETHYL) BENZALDEHYDE 2-CHLORO-3-(TRIFLUOROMETHYL)BENZOYL CHLORIDE 2-CHLORO-3-(TRIFLUOROMETHYL)BENZAMIDE 2-CHLORO-3-(TRIFLUOROMETHYL)PHENYL ACETATE 2-CHLORO-6-(TRIFLUOROMETHYL)BENZALDEHYDE 5-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE

2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE

TIMTEC-BB SBB003469

2-Chloro-3-(trifluoromethyl)benzaldehyde 98%

2-Chloro-3-(trifluoromethyl)benzaldehyde98%

2-Choro-3-(trifluoroMethyl)benzaldehyde

2-Fluoro-4-hydroxybenzonitrile

Benzaldehyde, 2-chloro-3-(trifluoromethyl)-

2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE ISO 9001：2015 REACH

3-Chloro-6-fluoroacetophenone

93118-03-7

C8H4CIF3O

ALDEHYDE

Organic Building Blocks

Carbonyl Compounds

Aldehydes

Building Blocks

Benzaldehyde

Aldehydes

Carbonyl Compounds