ChemicalBook > CAS DataBase List > CC-885
CC-885
- Product Name
- CC-885
- CAS No.
- 1010100-07-8
- Chemical Name
- CC-885
- Synonyms
- CC-885;Ligands for E3 Ligase,CC-885,CC 885,E3 ligase-recruiting Moiety,CC885,Inhibitor,inhibit;1-(3-Chloro-4-methylphenyl)-3-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)urea;Urea, N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-
- CBNumber
- CB13159377
- Molecular Formula
- C22H21ClN4O4
- Formula Weight
- 440.88
- MOL File
- 1010100-07-8.mol
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CC-885 Property
- solubility
- DMSO:40.0(Max Conc. mg/mL);90.72(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.45(Max Conc. mM)
DMF:12.5(Max Conc. mg/mL);28.35(Max Conc. mM) - form
- A crystalline solid
- color
- White to off-white
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 19966
- Product name
- CC-885
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $90
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 19966
- Product name
- CC-885
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $171
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 19966
- Product name
- CC-885
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $578
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 19966
- Product name
- CC-885
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $886
- Updated
- 2024/03/01
AK Scientific
- Product number
- 1485DC
- Product name
- 1-(3-Chloro-4-methylphenyl)-3-[[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]methyl]urea
- Packaging
- 1mg
- Price
- $293
- Updated
- 2021/12/16
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CC-885 Chemical Properties,Usage,Production
Description
CC-885 is a potent Cereblon Modulator with potent antitumor activity mediated through the degradation of GSPT1. was demonstrated to mediate antitumor effects through the recruitment and degradation of G1 to S phase transition 1 protein (GSPT1). GSPT1 (also named eRF3a) is a translation termination factor that binds eukaryotic translation termination factor 1 (eFR1) to mediate stop codon recognition and nascent protein release from the ribosome.
target
CC-885 is a cereblon (CRBN) modulator.
CC-885 Preparation Products And Raw materials
Raw materials
Preparation Products
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CC-885 Suppliers
- Tel
- 021-52996696，15000506266 15000506266
- Fax
- +86-21-52996696
- Country
- China
- ProdList
- 4512
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- Tel
- 021-61350663 13052117465
- Fax
- 021-61350662
- sales@zehanbiopharma.com
- Country
- China
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- 1009
- Advantage
- 55
- Tel
- 792-3901125 13222993784
- Fax
- 0512-62575043
- sales@unite-pharm.com
- Country
- China
- ProdList
- 295
- Advantage
- 56
- Tel
- 021-51619050 13301662590
- Fax
- +86-21-51619052
- mandy@atkchemical.com
- Country
- China
- ProdList
- 8026
- Advantage
- 55
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9806
- Advantage
- 58
- Tel
- 177-54423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 8011
- Advantage
- 62
- Tel
- 21-31433387 15618786686
- Fax
- QQ:1369748377
- sales@rechemscience.com
- Country
- China
- ProdList
- 2993
- Advantage
- 58
- Tel
- 021-QQ：65489617 15618227136
- Fax
- 21-5161 9052
- Sales@ATKchemical.com
- Country
- China
- ProdList
- 7266
- Advantage
- 58
- Tel
- 010-50973130 4009686088
- 3193328036@qq.com
- Country
- China
- ProdList
- 29785
- Advantage
- 68
- Tel
- 0550-5196001 15000891977
- Fax
- 0550-5196001
- wj520wjxby@126.com
- Country
- China
- ProdList
- 1847
- Advantage
- 55
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