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ALPHA-BUNGAROTOXIN

Product Name
ALPHA-BUNGAROTOXIN
CAS No.
11032-79-4
Chemical Name
ALPHA-BUNGAROTOXIN
Synonyms
α-BuTX;ALPHA-BGT;ALPHA-BUTX;α-Bungotoxin;A-BUNGAROTOXIN;α-Bungarotoxin;ALPHA-BUNGAROTOXIN;TIANFU-CHEM - ALPHA-BUNGAROTOXIN;M.W. 7984.14 C338H529N97O105S11;BUNGARUS MULTICINCTUS TOXIN, ALPHA
CBNumber
CB1331318
Molecular Formula
C50H70O14
Formula Weight
895.0824
MOL File
11032-79-4.mol
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ALPHA-BUNGAROTOXIN Property

storage temp. 
−20°C
solubility 
Soluble in sterile water
form 
solid
color 
white
Water Solubility 
Soluble in water
Sequence
Ile-Val-Cys-His-Thr-Thr-Ala-Thr-Ser-Pro-Ile-Ser-Ala-Val-Thr-Cys-Pro-Pro-Gly-Glu-Asn-Leu-Cys-Tyr-Arg-Lys-Met-Trp-Cys-Asp-Ala-Phe-Cys-Ser-Ser-Arg-Gly-Lys-Val-Val-Glu-Leu-Gly-Cys-Ala-Ala-Thr-Cys-Pro-Ser-Lys-Lys-Pro-Tyr-Glu-Glu-Val-Thr-Cys-Cys-Ser-Thr-Asp-Lys-Cys-Asn-Pro-His-Pro-Lys-Gln-Arg-Pro-Gly (Disulfide bridge: Cys3-Cys23;Cys16-Cys44;Cys29-Cys33;Cys48-Cys59;Cys60-Cys65)
InChIKey
LYTCVQQGCSNFJU-UHFFFAOYSA-N
CAS DataBase Reference
11032-79-4
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Safety

WGK Germany 
3
RTECS 
QQ4495249
Toxicity
chicken,LD50,intramuscular,74ug/kg (0.074mg/kg),Toxicon. Vol. 7, Pg. 89, 1969.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
203980
Product name
α-Bungarotoxin,
Packaging
1mg
Price
$214
Updated
2025/07/31
Cayman Chemical
Product number
16385
Product name
α-Bungarotoxin
Purity
≥99%
Packaging
1mg
Price
$149
Updated
2021/12/16
Tocris
Product number
2133
Product name
alpha-Bungarotoxin
Packaging
1
Price
$187
Updated
2021/12/16
ApexBio Technology
Product number
B6950
Product name
α-Bungarotoxin
Packaging
1mg
Price
$207
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
TOX0000441
Product name
ALPHA-BUNGAROTOXIN
Purity
95.00%
Packaging
5MG
Price
$501.36
Updated
2021/12/16
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ALPHA-BUNGAROTOXIN Chemical Properties,Usage,Production

Chemical Properties

Single polypeptide weight; molecular weight of 8000.

Definition

A protein that binds specifically to acetylcholine receptors.

General Description

Blocks neuromuscular transmission by irreversible binding to motor end-plate acetylcholine receptor (Kd = 1 pM to 1 nM) but does not depress acetylcholine release from motor nerve endings. Blocks nicotine-induced increase of intracellular Ca2+ in PC12 cells (IC50 = 310 nM), and prevents opening of nicotinic receptor-associated ion channels. Reconstitution experiments in Xenopus oocytes have shown the effects of α-bungarotoxin on neuronal nAChR to be highly specific for the α7-subtype (IC50 = 1.6 nM), but not for the α3β4-subtype (IC50 >3 μM).

Hazard

Nuerotoxic.

Biochem/physiol Actions

Product does not compete with ATP.

storage

-20°C (desiccate)

ALPHA-BUNGAROTOXIN Preparation Products And Raw materials

Raw materials

Preparation Products

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ALPHA-BUNGAROTOXIN Suppliers

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11032-79-4, ALPHA-BUNGAROTOXINRelated Search:

ALPHA-ACETYLDIGOXIN Tosylmethyl isocyanide SALCOMINE COBALT(II) ACETYLACETONATE Aluminum acetylacetonate Ferric acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) N-BUTYLISOCYANIDE PHENYLSELENOL TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE METHYL ISOCYANOACETATE Benzyl isocyanide Cupric acetylacetonate Tris(2,4-pentanedionato)chroMiuM(III) TERT-BUTYL ISOCYANIDE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) 2,4-PENTANEDIONE, SILVER DERIVATIVE

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  • ALPHA-BUNGAROTOXIN, BUNGARUS MULTICINCTUS
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  • ALPHA-BGT
  • A-BUNGAROTOXIN
  • M.W. 7984.14 C338H529N97O105S11
  • H-ILE-VAL-CYS-HIS-THR-THR-ALA-THR-SER-PRO-ILE-SER-ALA-VAL-THR-CYS-PRO-PRO-GLY-GLU-ASN-LEU-CYS-TYR-ARG-LYS-MET-TRP-CYS-ASP-ALA-PHE-CYS-SER-SER-ARG-GLY-LYS-VAL-VAL-GLU-LEU-GLY-CYS-ALA-ALA-THR-CYS-PRO-SER-LYS-LYS-PRO-TYR-GLU-GLU-VAL-THR-CYS-CYS-SER-THR-ASP-LYS-CYS-ASN-PRO-HIS-PRO-LYS-GLN-ARG-PRO-GLY-OH
  • BUNGARUS MULTICINCTUS TOXIN, ALPHA
  • A-BUNGAROTOXIN FROM THE VENOM OF THE
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  • α-Bungarotoxin, Bungarus multicinctus - CAS 11032-79-4 - Calbiochem
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  • α-Bungarotoxin
  • TIANFU-CHEM - ALPHA-BUNGAROTOXIN
  • α-Bungarotoxin, <i>Bungarus multicinctus</i>
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  • Acetylcholine receptor