ALPHA-BUNGAROTOXIN

Product Name: ALPHA-BUNGAROTOXIN
CAS No.: 11032-79-4
Chemical Name: ALPHA-BUNGAROTOXIN
Synonyms: α-BuTX;ALPHA-BGT;ALPHA-BUTX;α-Bungotoxin;A-BUNGAROTOXIN;α-Bungarotoxin;ALPHA-BUNGAROTOXIN;TIANFU-CHEM - ALPHA-BUNGAROTOXIN;M.W. 7984.14 C338H529N97O105S11;BUNGARUS MULTICINCTUS TOXIN, ALPHA
CBNumber: CB1331318
Molecular Formula: C50H70O14
Formula Weight: 895.0824
MOL File: 11032-79-4.mol

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ALPHA-BUNGAROTOXIN Property

storage temp.: −20°C
solubility: Soluble in sterile water
form: solid
color: white
Water Solubility: Soluble in water
CAS DataBase Reference: 11032-79-4

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Safety

WGK Germany: 3
RTECS: QQ4495249
Toxicity: chicken,LD50,intramuscular,74ug/kg (0.074mg/kg),Toxicon. Vol. 7, Pg. 89, 1969.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 203980
Product name: α-Bungarotoxin,
Packaging: 1mg
Price: $208
Updated: 2024/03/01

Cayman Chemical

Product number: 16385
Product name: α-Bungarotoxin
Purity: ≥99%
Packaging: 1mg
Price: $149
Updated: 2021/12/16

Tocris

Product number: 2133
Product name: alpha-Bungarotoxin
Packaging: 1
Price: $187
Updated: 2021/12/16

ApexBio Technology

Product number: B6950
Product name: α-Bungarotoxin
Packaging: 1mg
Price: $207
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: TOX0000441
Product name: ALPHA-BUNGAROTOXIN
Purity: 95.00%
Packaging: 5MG
Price: $501.36
Updated: 2021/12/16

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ALPHA-BUNGAROTOXIN Chemical Properties,Usage,Production

Chemical Properties

Single polypeptide weight; molecular weight of 8000.

Definition

A protein that binds specifically to acetylcholine receptors.

General Description

Blocks neuromuscular transmission by irreversible binding to motor end-plate acetylcholine receptor (K_d = 1 pM to 1 nM) but does not depress acetylcholine release from motor nerve endings. Blocks nicotine-induced increase of intracellular Ca²⁺ in PC12 cells (IC₅₀ = 310 nM), and prevents opening of nicotinic receptor-associated ion channels. Reconstitution experiments in Xenopus oocytes have shown the effects of α-bungarotoxin on neuronal nAChR to be highly specific for the α₇-subtype (IC₅₀ = 1.6 nM), but not for the α₃β₄-subtype (IC₅₀ >3 μM).

Hazard

Nuerotoxic.

Biochem/physiol Actions

Product does not compete with ATP.

storage

-20°C (desiccate)

ALPHA-BUNGAROTOXIN Preparation Products And Raw materials

Raw materials

Preparation Products

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ALPHA-BUNGAROTOXIN Suppliers

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11032-79-4, ALPHA-BUNGAROTOXINRelated Search:

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ALPHA-BUNGAROTOXIN

ALPHA-BUNGAROTOXIN, BUNGARUS MULTICINCTUS

ALPHA-BUTX

ALPHA-BGT

A-BUNGAROTOXIN

M.W. 7984.14 C338H529N97O105S11

H-ILE-VAL-CYS-HIS-THR-THR-ALA-THR-SER-PRO-ILE-SER-ALA-VAL-THR-CYS-PRO-PRO-GLY-GLU-ASN-LEU-CYS-TYR-ARG-LYS-MET-TRP-CYS-ASP-ALA-PHE-CYS-SER-SER-ARG-GLY-LYS-VAL-VAL-GLU-LEU-GLY-CYS-ALA-ALA-THR-CYS-PRO-SER-LYS-LYS-PRO-TYR-GLU-GLU-VAL-THR-CYS-CYS-SER-THR-ASP-LYS-CYS-ASN-PRO-HIS-PRO-LYS-GLN-ARG-PRO-GLY-OH

BUNGARUS MULTICINCTUS TOXIN, ALPHA

A-BUNGAROTOXIN FROM THE VENOM OF THE

α-BuTX

α-Bungarotoxin, Bungarus multicinctus - CAS 11032-79-4 - Calbiochem

α-Bungotoxin

α-Bungarotoxin

TIANFU-CHEM - ALPHA-BUNGAROTOXIN

11032-79-4

C338H529N97O105S11

Acetylcholine receptor