5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile

Product Name: 5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile
CAS No.: 80025-67-8
Chemical Name: 5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile
Synonyms: Xanthine oxidase-IN-14;Xanthine dehydrogenase Inhibitor 1;5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile;1H-Pyrazole-4-carbonitrile, 5-amino-1-[4-(trifluoromethyl)phenyl]-;5-amino-1-[4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbonitrile, 10 mM in DMSO;5 amino 1 [4 (trifluoromethyl)phenyl] 1H pyrazole 4 carbonitrile,5amino1[4(trifluoromethyl)phenyl]1Hpyrazole4carbonitrile
CBNumber: CB13314772
Molecular Formula: C11H7F3N4
Formula Weight: 252.2
MOL File: 80025-67-8.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 161389
Product name: 5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile
Purity: 95%+
Packaging: 1g
Price: $877
Updated: 2021/12/16

AK Scientific

Product number: 2554CU
Product name: 5-Amino-1-(4-(trifluoromethyl)phenyl)-1H-pyrazole-4-carbonitrile
Packaging: 2.5g
Price: $1197
Updated: 2021/12/16

Acints

Product number: ACI-04011
Product name: 5-Amino-1-(4-trifluoromethyl-phenyl)-1H-pyrazole-4-carbonitrile
Purity: 95%+
Packaging: 1g
Price: $427.75
Updated: 2021/12/16

Advanced Chemicals Intermediatesced Chemicals Intermediates

Product number: ACI-04011
Product name: 5-Amino-1-(4-trifluoromethyl-phenyl)-1H-pyrazole-4-carbonitrile
Purity: 95%+
Packaging: 1g
Price: $427.75
Updated: 2021/12/16

Crysdot

Product number: CD11054963
Product name: 5-Amino-1-(4-(trifluoromethyl)phenyl)-1H-pyrazole-4-carbonitrile
Purity: 97%
Packaging: 1g
Price: $434
Updated: 2021/12/16

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5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile Chemical Properties,Usage,Production

Uses

Xanthine oxidase-IN-14 (Compound 3f) is an inhibitor for xanthine oxidase, with IC50 >100 μM. Xanthine oxidase-IN-14 inhibits proliferations of cancer cells MCF-7, NCI-H460 and SF-268, with IC50 greater than 150 μM[1].

References

[1] Gupta S, et al., Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors. Eur J Med Chem. 2008 Apr;43(4):771-80. DOI:10.1016/j.ejmech.2007.06.002

5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile Preparation Products And Raw materials

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80025-67-8, 5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrileRelated Search:

Benzaldehyde, 5-fluoro-2-[[1-[(3-methoxyphenyl)methyl]-1H-1,2,3-triazol-4-yl]methoxy]- Benzonitrile, 5-(2,3-dihydro-3-oxo-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-2-(1-methylethoxy)- Benzamide, N-(4-chlorophenyl)-4-(1H-tetrazol-5-yl)- XANTHOSINE DIHYDRATE 1H-Indole-3-carbonitrile, 1-cyclopentyl-5-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)- Xanthyletin Acetamide, N-(2-aminoethyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-, hydrochloride (1:1)

5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile

1H-Pyrazole-4-carbonitrile, 5-amino-1-[4-(trifluoromethyl)phenyl]-

5 amino 1 [4 (trifluoromethyl)phenyl] 1H pyrazole 4 carbonitrile,5amino1[4(trifluoromethyl)phenyl]1Hpyrazole4carbonitrile

Xanthine oxidase-IN-14

Xanthine dehydrogenase Inhibitor 1

5-amino-1-[4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbonitrile, 10 mM in DMSO

80025-67-8