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1H-Indole-3-carbonitrile, 1-cyclopentyl-5-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)-

Product Name
1H-Indole-3-carbonitrile, 1-cyclopentyl-5-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)-
CAS No.
2411698-59-2
Chemical Name
1H-Indole-3-carbonitrile, 1-cyclopentyl-5-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)-
Synonyms
Xanthine oxidase-IN-7;1H-Indole-3-carbonitrile, 1-cyclopentyl-5-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)-
CBNumber
CB712917533
Molecular Formula
C16H14N4O2
Formula Weight
294.31
MOL File
2411698-59-2.mol
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1H-Indole-3-carbonitrile, 1-cyclopentyl-5-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)- Property

Density 
1.49±0.1 g/cm3(Predicted)
pka
6.54±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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1H-Indole-3-carbonitrile, 1-cyclopentyl-5-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)- Chemical Properties,Usage,Production

Uses

Xanthine oxidase-IN-7 (compound1h) is a potent andorally active XO (xanthine oxidase) inhibitor with an IC50 of 0.36 μM. Xanthine oxidase-IN-7 effectively reduces serum uric acid levels. Xanthine oxidase-IN-7 has the potential for the research of hyperuricemia and gout[1].

References

[1] Gao J, et al. Design, synthesis and biological evaluation of 1-alkyl-5/6-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-1H-indole-3-carbonitriles as novel xanthine oxidase inhibitors. Eur J Med Chem. 2020 Mar 15;190:112077. DOI:10.1016/j.ejmech.2020.112077

1H-Indole-3-carbonitrile, 1-cyclopentyl-5-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Indole-3-carbonitrile, 1-cyclopentyl-5-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)- Suppliers

China 1 United States 1 Global 2
TargetMol Chemicals Inc.
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15002134094
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marketing@targetmol.cn
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China
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TargetMol Chemicals Inc.
Tel
+17819995354
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marketing@targetmol.com
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United States
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2411698-59-2, 1H-Indole-3-carbonitrile, 1-cyclopentyl-5-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)-Related Search:

Benzaldehyde, 5-fluoro-2-[[1-[(3-methoxyphenyl)methyl]-1H-1,2,3-triazol-4-yl]methoxy]- 5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile Benzonitrile, 5-(2,3-dihydro-3-oxo-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-2-(1-methylethoxy)- Benzamide, N-(4-chlorophenyl)-4-(1H-tetrazol-5-yl)- XANTHOSINE DIHYDRATE Xanthyletin Acetamide, N-(2-aminoethyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-, hydrochloride (1:1)

  • 1H-Indole-3-carbonitrile, 1-cyclopentyl-5-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)-
  • Xanthine oxidase-IN-7
  • 2411698-59-2