(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Product Name: (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
CAS No.: 1987887-92-2
Chemical Name: (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Synonyms: Nintedanib-011;Intedanib Impurity D;Nintedanib Impurity q;Nintedanib Impurity 34;Nintedanib impuritiesD;Nintedanib Impurity N4;Nintedanib impurities25;NintedanibN-Methylimpurity;Nintedanib N-Methyl Aniline Analog;(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)meth...
CBNumber: CB13335038
Molecular Formula: C24H21N3O3
Formula Weight: 399.44
MOL File: 1987887-92-2.mol

More

Less

(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Property

Melting point:: 273 - 276°C
Boiling point:: 641.3±55.0 °C(Predicted)
Density: 1.316±0.06 g/cm3(Predicted)
storage temp.: Refrigerator, under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 11.16±0.20(Predicted)
form: Solid
color: Yellow to Orange

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

TRC

Product number: D492443
Product name: (3Z)-2,3-Dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylicAcidMethylEster
Packaging: 5mg
Price: $255
Updated: 2021/12/16

More

Less

(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Chemical Properties,Usage,Production

Uses

(3Z)?-2,?3-Dihydro-?3-?[[[4-?(methylamino)?phenyl]?amino]?phenylmethylene]?-?2-?oxo-?1H-?Indole-?6-?carboxylic Acid Methyl Ester is an impurity of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Suppliers

China 43 India 4 United States 4 Global 51

Beijing Comparison Pharmaceutical Technology Co., Ltd

Tel: 010-010-52878169 15801002657
Email: sales@bjcomparison.com
Country: China
ProdList: 4990
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18042
Advantage: 56

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-66023220 0086-15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
ProdList: 7850
Advantage: 55

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Shanghai Han-Xiang Chemical Co., Ltd.

Tel: 15971444841
Fax: 18327183813
Email: amber@biochempartner.com
Country: China
ProdList: 3061
Advantage: 58

Shandong Chengchuang Blue Sea Pharmaceutical Technology Co., Ltd.

Tel: 0531-58897130 15508676053
Email: drug_impurity@sdcclh.com
Country: China
ProdList: 2007
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57412
Advantage: 58

TOSUN PHARM

Tel: 020-61855200 13326451905
Email: 260366801@qq.com
Country: China
ProdList: 7781
Advantage: 58

Jinan Baizhou Biological Technology Co., Ltd.

Tel: 0531-88987162 18615427082
Email: 2823799053@qq.com
Country: China
ProdList: 497
Advantage: 58

1987887-92-2, (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylateRelated Search:

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester 1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester Nintedanib Methyl oxindole-5-carboxylate N-(4-aMinophenyl)-2-chloro-N-MethylacetaMide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID ETHYL ESTER Methyl 1-acetyl-2-oxoindoline-6-carboxylate 1-Chloro-4-(trimethoxymethyl)benzene METHYL OXINDOLE-7-CARBOXYLATE P-ANISALDEHYDE DIMETHYL ACETAL 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate BIBF 1202 N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide Methyl 4-chloro-3-nitrobenzoate

Intedanib Impurity D

Nintedanib Impurity 34

Nintedanib-011

Nintedanib impurity 10/(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)meth...

1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)-

Nintedanib Impurity q

(3Z)?-2,?3-Dihydro-?3-?[[[4-?(methylamino)?phenyl]?amino]?phenylmethylene]?-?2-?oxo-?1H-?Indole-?6-?carboxylic Acid Methyl Ester

(Z)-Methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate (Nintedanib Impurity)

(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylen...

Nintedanib impurities25

Nintedanib impuritiesD

NintedanibN-Methylimpurity

Nintedanib N-Methyl Aniline Analog

(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Nintedanib Impurity N4

1987887-92-2