Adenine hydrochloride
- Product Name
- Adenine hydrochloride
- CAS No.
- 2922-28-3
- Chemical Name
- Adenine hydrochloride
- Synonyms
- ADENINE HCL;6-AMINOPURINE HCL;ADENINIUM CHLORIDE;TIMTEC-BB SBB003841;Adenine hydrocloride;ADENINE HYDROCHLORIDE;7H-adenine hydrochloride;ADENINE MONOHYDROCHLORIDE;Adenine hydrochloride ,98%;6-AMINOPURINE HYDROCHLORIDE
- CBNumber
- CB1334849
- Molecular Formula
- C5H6ClN5
- Formula Weight
- 171.59
- MOL File
- 2922-28-3.mol
Adenine hydrochloride Property
- Melting point:
- ~285 °C (dec.)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- H2O: 50 mg/mL
- form
- powder
- color
- White to Off-White
- Merck
- 14,152
- BRN
- 4009585
- CAS DataBase Reference
- 2922-28-3(CAS DataBase Reference)
- EPA Substance Registry System
- 1H-Purin-6-amine, monohydrochloride (2922-28-3)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36-36/37/39-24/25
- WGK Germany
- 3
- F
- 3-8
- TSCA
- Yes
- HS Code
- 29335990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P321Specific treatment (see … on this label).
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A8751
- Product name
- Adenine hydrochloride hydrate
- Purity
- ≥99%
- Packaging
- 1g
- Price
- $40.08
- Updated
- 2024/03/01
- Product number
- 01840
- Product name
- Adenine monohydrochloride
- Purity
- ≥99.0% (HPLC)
- Packaging
- 25g
- Price
- $51
- Updated
- 2024/03/01
- Product number
- A0150
- Product name
- Adenine Hydrochloride Hemihydrate
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $27
- Updated
- 2022/04/27
- Product number
- A0150
- Product name
- Adenine Hydrochloride Hemihydrate
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $79
- Updated
- 2022/04/27
- Product number
- A17622
- Product name
- Adenine hydrochloride, 98+%, cont. up to ca 5% water
- Packaging
- 5g
- Price
- $24.65
- Updated
- 2024/03/01
Adenine hydrochloride Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powder
Uses
Adenine hydrochloride hydrate has been used:
- As a component of FAD cell culture media
- In maintaining organotypic cultures for recreating stratified epithelium from primary cell cultures
- In limbal-corneal epithelial culturing and keratinocytes
Uses
Adenine is a purine nucleobase with a wide range of chemical and biochemical roles in vivo and in vitro. It is a regulatory molecule and a component of DNA, RNA, cofactors (NAD, FAD) and signaling molecules (cAMP).
Biological Activity
adenine hcl, a purine derivative and a nucleobase, plays crucial roles in substantial biochemistry processes in vivo, including cellular respiration, formation of the energy-rich adenosine triphosphate (atp), the cofactors nicotinamide adenine dinucleotide (nad) and flavin adenine dinucleotide (fad) as well as protein synthesis. in addition, adenine hcl also serves as a chemical component of dna and rna. adenosine triphosphate is used in cellular metabolism as one of the basic methods of transferring chemical energy between chemical reactions. [1]
in vitro
the cyto-protective effect of adenosine was measured using an in vitro model of acute tubular necrosis in rat kidney tubular cells. the finding suggested that adenosine at the concentration of 100 m could significantly decrease cellular injury. the ec50 value of adenosine was detected to be 14 m. [2]
in vivo
a study was performed to investigate the effects of dietary adenine on fatty liver induced by orotic acid (oa) in rats. 1% oa-supplemented diets with/ without 0.25% adenine was administered to rats for 10 days. enzyme assay kits were then applied to measure serum lipid profiles of tested rats, such as liver lipid concentrations in different treatment groups. moreover, the activities of fatty acid synthase (fas) and fatty acid β-oxidation were also detected. the findings suggested that addition of adenine to the diet offset the effect of oa and reversed promotion of liver tg content to basal level. administration of adenine also inhibited fas activities in rat liver. in conclusion, the ameliorating of fatty liver in adenine-treated rats was associated with the reduction of fas activities accompanied with the increase of mitochondrial fatty acid β-oxidation and the promotion of serum lipid secretion from the hepatic tissue into the bloodstream. [1]
storage
Desiccate at RT
References
[1]buang y. dietary adenine alleviates fatty liver induced by orotic acid. indo. j. chem. 2010; 10 (3): 363 - 369.
[2] módis k, ger d, nagy n, szoleczky p, tóth zd and szabó c. cytoprotective effects of adenosine and inosine in an in vitro model of acute tubular necrosis. br j pharmacol. 2009 nov; 158(6): 1565–8.
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View Lastest Price from Adenine hydrochloride manufacturers
- Product
- ADENINE HYDROCHLORIDE HEMIHYDRATE 2922-28-3
- Price
- US $70.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 30 tons
- Release date
- 2023-07-05
- Product
- Adenine hydrochloride 2922-28-3
- Price
- US $60.00/KG
- Min. Order
- 25KG
- Purity
- 99.99%
- Supply Ability
- 200ton
- Release date
- 2023-08-15
- Product
- Adenine hydrochloride 2922-28-3
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2023-06-26