Fmoc-Lys (biotin-PEG4)-OH
- Product Name
- Fmoc-Lys (biotin-PEG4)-OH
- CAS No.
- 1334172-64-3
- Chemical Name
- Fmoc-Lys (biotin-PEG4)-OH
- Synonyms
- Fmoc-Lys (biotin-PEG4)-OH;Fmoc-Lys(dPEG(4)-Biotin)-OH;Fmoc-N-Lys-(dPEG??-biotin)-OH-(acid) (QBD-10613);N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-[15-(biotinamido)-4,7,10,13-tetraoxa-pentadecanoyl]-L-lysine;12,15,18,21-Tetraoxa-2,8,24-triazanonacosanoic acid, 3-carboxy-29-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-9,25-dioxo-, 1-(9H-fluoren-9-ylmethyl) ester, (3S)-
- CBNumber
- CB13363932
- Molecular Formula
- C42H59N5O11S
- Formula Weight
- 842.01
- MOL File
- 1334172-64-3.mol
Fmoc-Lys (biotin-PEG4)-OH Property
- Boiling point:
- 1105.7±65.0 °C(Predicted)
- Density
- 1.236±0.06 g/cm3(Predicted)
- pka
- 3.87±0.21(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F679878
- Product name
- Fmoc-N-Lys-(dPEG-biotin)-OH-(acid)
- Packaging
- 2mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 10613
- Product name
- Fmoc-N-Lys-(dPEG®₄-biotin)-OH-(acid)
- Packaging
- 100mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- BP-22612
- Product name
- Fmoc-Lys(biotin-PEG4)-OH
- Purity
- 98%
- Packaging
- 100mg
- Price
- $320
- Updated
- 2021/12/16
- Product number
- BIPG1393
- Product name
- Fmoc-Lys (biotin-PEG4)-OH
- Packaging
- 100mg
- Price
- $623
- Updated
- 2021/12/16
- Product number
- BP-22612
- Product name
- Fmoc-Lys(biotin-PEG4)-OH
- Purity
- 98%
- Packaging
- 250mg
- Price
- $650
- Updated
- 2021/12/16
Fmoc-Lys (biotin-PEG4)-OH Chemical Properties,Usage,Production
Description
Fmoc-Lys (biotin-PEG4)-OH is a Lysine embedded biotin PEG linkers containing a carboxylic group and Fmoc-protected amine. Reaction of carboxylic with primary amino (-NH2) forms stable, irreversible amide bonds. The Fmoc group can be deprotected under basic condition to release the free amine which can be used for further conjugations.
Uses
Fmoc-Lys (biotin-PEG4)-OH is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329
Fmoc-Lys (biotin-PEG4)-OH Preparation Products And Raw materials
Raw materials
Preparation Products
Fmoc-Lys (biotin-PEG4)-OH Suppliers
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