Fmoc-Leu-OH
- Product Name
- Fmoc-Leu-OH
- CAS No.
- 35661-60-0
- Chemical Name
- Fmoc-Leu-OH
- Synonyms
- FMOC-LEU-OH;FMOC-LEU;FMOC-L-LEU-OH;FMOC-LEUCINE;L-LEUCINE-N-FMOC;N-(fluorenyl-9-methoxycarbonyl)leucine;(S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-4-Methylpentanoic acid;F-L-LEU;NPC 15199;FMOC-L-LEU
- CBNumber
- CB5477829
- Molecular Formula
- C21H23NO4
- Formula Weight
- 353.41
- MOL File
- 35661-60-0.mol
Fmoc-Leu-OH Property
- Melting point:
- 152-156 °C(lit.)
- alpha
- -26 º (c=1,DMF 24 ºC)
- Boiling point:
- 486.83°C (rough estimate)
- Density
- 1.2107 (rough estimate)
- refractive index
- -25 ° (C=1, DMF)
- storage temp.
- Store below +30°C.
- solubility
- DMF (Slightly), DMSO (Slightly)
- form
- Solid
- pka
- 3.91±0.21(Predicted)
- color
- White to Off-White
- optical activity
- [α]20/D 25±2°, c = 1% in DMF
- BRN
- 2178254
- Stability:
- Hygroscopic
- InChIKey
- CBPJQFCAFFNICX-IBGZPJMESA-N
- CAS DataBase Reference
- 35661-60-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-24/25-36/37/39-27-26
- WGK Germany
- 3
- HS Code
- 2924 29 70
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8.52011
- Product name
- Fmoc-Leu-OH
- Purity
- Novabiochem?
- Packaging
- 25g
- Price
- $36.5
- Updated
- 2024/03/01
- Product number
- 8.52011
- Product name
- Fmoc-Leu-OH
- Purity
- Novabiochem?
- Packaging
- 100g
- Price
- $70
- Updated
- 2024/03/01
- Product number
- 8.52011
- Product name
- Fmoc-Leu-OH
- Purity
- Novabiochem?
- Packaging
- 250g
- Price
- $162
- Updated
- 2024/03/01
- Product number
- 8.52011
- Product name
- Fmoc-Leu-OH
- Purity
- Novabiochem?
- Packaging
- 1kg
- Price
- $489
- Updated
- 2024/03/01
- Product number
- 47633
- Product name
- Fmoc-Leu-OH
- Purity
- ≥97.0%
- Packaging
- 5G
- Price
- $32.3
- Updated
- 2024/03/01
Fmoc-Leu-OH Chemical Properties,Usage,Production
Description
Fmoc-Leu-OH is isomeric with Fmoc-Ile-OH. Like isoleucine, leucine has branching in the sidechain. The branching is at the gamma carbon instead of the beta carbon as in isoleucine. It is used in chemical and peptide syntheses.
Chemical Properties
white to light yellow crystal powde
Uses
Fmoc-L-Leu-OH, is an amino acid derivative, used in peptide chemistry. It is also one of the novel PPARγ ligands that can activate PPARγ in different ways, that reduces osteoclasts differentiation, and thus are better therapeutic targets in diabetes than traditional antidiabetic drugs.
Application
Fmoc-Leu-OH can be used as a reactant to synthesize:
Various oligopeptides by reacting with functionalized α-amino acid hydrochloride salts.
A cyclic depsipeptide sansalvamide A, a natural product found in marine fungus.
Streptocidin A?D, decapeptide antibiotics naturally found in Streptomyces?sp. Tü 6071.
Coumaroyl dipeptide amide that can be used for cosmetic applications.
Preparation
Fmoc-L-leucine is prepared by reacting L-leucine with 9-fluorenylmethoxycarbonyl chloride.
Biological Activity
Anti-inflammatory agent; increases intracellular Ca 2+ levels. PPARγ ligand that induces insulin sensitization, but not adipogenesis.
Fmoc-Leu-OH Preparation Products And Raw materials
Raw materials
Preparation Products
Fmoc-Leu-OH Suppliers
- Tel
- 021-61263455 13167021076
- amy@glschina.com
- Country
- China
- ProdList
- 8745
- Advantage
- 58
- Tel
- 0519-85720003 18861157602
- Fax
- 0519-85720007
- sales03@genchem.cn
- Country
- China
- ProdList
- 111
- Advantage
- 58
- Tel
- 13347833233
- 120300346@qq.com
- Country
- China
- ProdList
- 31
- Advantage
- 58
- Tel
- 13356310019 13356310019
- boyu2024@163.com
- Country
- China
- ProdList
- 2735
- Advantage
- 58
- Tel
- 028-61682518; 19983060238
- sales@tachem.cn
- Country
- China
- ProdList
- 103
- Advantage
- 58
- Tel
- 13383293380 18032131480
- 649498984@qq.com
- Country
- China
- ProdList
- 75
- Advantage
- 58
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 94657
- Advantage
- 76
- Tel
- 025-86918202 4000255188
- Fax
- 86-025-86918232
- sales@pharmablock.com
- Country
- China
- ProdList
- 4986
- Advantage
- 55
- Tel
- 021-61259108 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15839
- Advantage
- 69
View Lastest Price from Fmoc-Leu-OH manufacturers
- Product
- Fmoc-L-leu-OH 35661-60-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T
- Release date
- 2023-12-11
- Product
- FMOC-L-Leucine 35661-60-0
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1000kg
- Release date
- 2021-08-28
- Product
- Fmoc-Leu-OH 35661-60-0
- Price
- US $0.00/gram
- Min. Order
- 25gram
- Purity
- 99% HPLC
- Supply Ability
- 25 gram
- Release date
- 2023-10-16