ChemicalBook > CAS DataBase List > Fmoc-Leu-OH

Fmoc-Leu-OH

Product Name
Fmoc-Leu-OH
CAS No.
35661-60-0
Chemical Name
Fmoc-Leu-OH
Synonyms
FMOC-LEU-OH;FMOC-LEU;FMOC-L-LEU-OH;FMOC-LEUCINE;L-LEUCINE-N-FMOC;N-(fluorenyl-9-methoxycarbonyl)leucine;(S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-4-Methylpentanoic acid;F-L-LEU;NPC 15199;FMOC-L-LEU
CBNumber
CB5477829
Molecular Formula
C21H23NO4
Formula Weight
353.41
MOL File
35661-60-0.mol
More
Less

Fmoc-Leu-OH Property

Melting point:
152-156 °C(lit.)
alpha 
-26 º (c=1,DMF 24 ºC)
Boiling point:
486.83°C (rough estimate)
Density 
1.2107 (rough estimate)
refractive index 
-25 ° (C=1, DMF)
storage temp. 
Store below +30°C.
solubility 
DMF (Slightly), DMSO (Slightly)
form 
Solid
pka
3.91±0.21(Predicted)
color 
White to Off-White
optical activity
[α]20/D 25±2°, c = 1% in DMF
BRN 
2178254
Stability:
Hygroscopic
InChIKey
CBPJQFCAFFNICX-IBGZPJMESA-N
CAS DataBase Reference
35661-60-0(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36/37/39-27-26
WGK Germany 
3
HS Code 
2924 29 70
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.52011
Product name
Fmoc-Leu-OH
Purity
Novabiochem?
Packaging
25g
Price
$36.5
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52011
Product name
Fmoc-Leu-OH
Purity
Novabiochem?
Packaging
100g
Price
$70
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52011
Product name
Fmoc-Leu-OH
Purity
Novabiochem?
Packaging
250g
Price
$162
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52011
Product name
Fmoc-Leu-OH
Purity
Novabiochem?
Packaging
1kg
Price
$489
Updated
2024/03/01
Sigma-Aldrich
Product number
47633
Product name
Fmoc-Leu-OH
Purity
≥97.0%
Packaging
5G
Price
$32.3
Updated
2024/03/01
More
Less

Fmoc-Leu-OH Chemical Properties,Usage,Production

Description

Fmoc-Leu-OH is isomeric with Fmoc-Ile-OH. Like isoleucine, leucine has branching in the sidechain. The branching is at the gamma carbon instead of the beta carbon as in isoleucine. It is used in chemical and peptide syntheses.

Chemical Properties

white to light yellow crystal powde

Uses

Fmoc-L-Leu-OH, is an amino acid derivative, used in peptide chemistry. It is also one of the novel PPARγ ligands that can activate PPARγ in different ways, that reduces osteoclasts differentiation, and thus are better therapeutic targets in diabetes than traditional antidiabetic drugs.

Application

Fmoc-Leu-OH can be used as a reactant to synthesize:
Various oligopeptides by reacting with functionalized α-amino acid hydrochloride salts.
A cyclic depsipeptide sansalvamide A, a natural product found in marine fungus.
Streptocidin A?D, decapeptide antibiotics naturally found in Streptomyces?sp. Tü 6071.
Coumaroyl dipeptide amide that can be used for cosmetic applications.

Preparation

Fmoc-L-leucine is prepared by reacting L-leucine with 9-fluorenylmethoxycarbonyl chloride.

Biological Activity

Anti-inflammatory agent; increases intracellular Ca 2+ levels. PPARγ ligand that induces insulin sensitization, but not adipogenesis.

Fmoc-Leu-OH Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Fmoc-Leu-OH Suppliers

Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58
GLR Innovations
Tel
+91 9891111994
Email
info@glrgroup.in
Country
India
ProdList
4535
Advantage
58
TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
Globe Chemie
Tel
--
Fax
--
Email
info@globechemie.co.in
Country
India
ProdList
293
Advantage
50
Sisco Research Laboratories Pvt. Ltd.
Tel
--
Fax
--
Email
marketing@srlchem.com
Country
India
ProdList
4315
Advantage
58
Siddhi Vinayaka Spechem Private Limited
Tel
--
Fax
--
Email
rtassociates11@gmail.com
Country
India
ProdList
23
Advantage
58
Triveni chemicals
Tel
--
Fax
--
Email
sales@trivenichemical.com
Country
India
ProdList
6088
Advantage
58
Santo Righello Pvt. Ltd
Tel
--
Fax
--
Email
marketing@santorighello.com
Country
India
ProdList
918
Advantage
58
Divis Laboratories Ltd.
Tel
--
Fax
--
Country
India
ProdList
147
Advantage
58
Vishnu Chemicals Limited
Tel
--
Fax
--
Country
India
ProdList
76
Advantage
58
Sisco Resech Laboratories Private Limited
Tel
--
Fax
--
Country
India
ProdList
655
Advantage
58
Advent Chembio Pvt., Ltd.
Tel
--
Fax
--
Email
sales@adventchembio.com
Country
India
ProdList
623
Advantage
58
APAC Sourcing Solutions Ltd.
Tel
--
Fax
--
Email
arjunsrivastava@apacss.com
Country
India
ProdList
61
Advantage
58
Globe Chemie
Tel
--
Fax
--
Country
India
ProdList
101
Advantage
58
Cjex Biochem Private Limited
Tel
--
Fax
--
Country
India
ProdList
14
Advantage
58
Spectrochem Private Limited
Tel
--
Fax
--
Country
India
ProdList
1055
Advantage
58
VASIN BIO LIFE SCIENCES PVT LTD
Tel
--
Fax
--
Email
info@vasinbio.com
Country
India
ProdList
2092
Advantage
58
Bhavesh Chem Labs
Tel
--
Fax
--
Country
India
ProdList
26
Advantage
58
Divis Laboratories Limited
Tel
--
Fax
--
Country
India
ProdList
28
Advantage
58
Souvenier Chemicals
Tel
--
Fax
--
Country
India
ProdList
396
Advantage
58
CJEX Biochem Pvt., Ltd.
Tel
--
Fax
--
Email
info@cjexchem.com
Country
India
ProdList
9
Advantage
58
Suyara Inds. Pvt. Ltd.
Tel
--
Fax
--
Email
paresh.patil@suyaraindustries.com
Country
India
ProdList
33
Advantage
58
ASM Organics
Tel
--
Fax
--
Country
India
ProdList
1185
Advantage
58
Siddhi Vinayaka Spechem Private Limited
Tel
--
Fax
--
Country
India
ProdList
24
Advantage
58
Siddhi Specialities
Tel
--
Fax
--
Email
siddhispecialities@gmail.com
Country
India
ProdList
162
Advantage
58
Maas Pharma Chemicals
Tel
--
Fax
--
Email
info@maaspharmachemicals.com
Country
India
ProdList
1607
Advantage
58
Venkateshwara Life Sciences
Tel
--
Fax
--
Country
India
ProdList
61
Advantage
58
Anand Agencies
Tel
--
Fax
--
Email
en@gmail.com
Country
India
ProdList
2332
Advantage
58
Reax Chemicals
Tel
--
Fax
--
Country
India
ProdList
4217
Advantage
58
AP Vishwa Chemicals LLP
Tel
--
Fax
--
Country
India
ProdList
7
Advantage
58
Central Drug House(P) Ltd.
Tel
--
Fax
--
Email
sales@cdhfinechemical.com
Country
India
ProdList
6157
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
Avra Synthesis Pvt Ltd
Tel
--
Fax
--
Email
info@avrasynthesis.com
Country
India
ProdList
1603
Advantage
30
Venkateshwara Life Sciences
Tel
--
Fax
--
Email
balakrishna@venkateshwaralifesciences.com
Country
India
ProdList
88
Advantage
50
CHEMSWORTH
Tel
--
Fax
--
Email
info@chemsworth.com
Country
India
ProdList
6700
Advantage
30
More
Less

View Lastest Price from Fmoc-Leu-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Fmoc-L-leu-OH 35661-60-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2023-12-11
WUHAN FORTUNA CHEMICAL CO., LTD
Product
FMOC-L-Leucine 35661-60-0
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kg
Release date
2021-08-28
Wuhan Senwayer Century Chemical Co.,Ltd
Product
Fmoc-Leu-OH 35661-60-0
Price
US $0.00/gram
Min. Order
25gram
Purity
99% HPLC
Supply Ability
25 gram
Release date
2023-10-16

35661-60-0, Fmoc-Leu-OHRelated Search:


  • FMOC-LEU-OH
  • FMOC-L-LEU-OH
  • FMOC-L-LEU
  • FMOC-L-LEUCINE
  • F-L-LEU
  • Fmoc-L-leucine,98%
  • L-Leucine-1-13C-N-FMOC
  • Fmoc-N-(isobutyl)-glycine
  • N-(fluorenyl-9-methoxycarbonyl)leucine
  • FMOC-L-LEU-OH MONOHYDRATE
  • Fmoc-N-(isobutyl)-Gly-OH
  • FMOC-L-LEUCINE extrapure
  • N-(9-Fluorenylmethoxycarbonyl)-L-leucine, Fmoc-L-leucine
  • 2-(9H-fFuoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucine ,98%
  • (2S)-4-Methyl-2-(9H-fluorene-9-ylmethoxycarbonylamino)valeric acid
  • (S)-2-[[(9H-Fluorene-9-yl)methoxycarbonyl]amino]-4-methylpentanoic acid
  • N-[(9H-Fluorene-9-yl)methoxycarbonyl]leucine
  • FMoc-L-leucine FMoc-Leu-OH
  • 2-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO]-4-METHYLPENTANOIC ACID
  • 9-FLUORENYLMETHOXYCARBONYL-L-LEUCINE
  • FMOC-LEU
  • FMOC-LEUCINE
  • Fmoc-Leucine-OH
  • FMoc-Nleu-OH
  • N-FMOC-LEU-OH
  • N-FMOC-L-LEU
  • N-FMOC-L-LEUCINE
  • NPC 15199
  • N-ALPHA-FMOC-L-LEUCINE
  • N-(9-FLUORENYLMETHOXYCARBONYL)-L-LEUCINE
  • N-9-FLUORENYLMETHYLOXYCARBONYL-L-LEUCINE
  • N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-LEUCINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-LEUCINE
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-LEUCINE
  • PPAR-GAMMA ACTIVATOR
  • (S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-4-Methylpentanoic acid
  • N-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-L-leucine, (2S)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanoic acid
  • N-Fmoc-L-leucine Fmoc-Leu-OH
  • FMoc-Leu-OH >=97.0%
  • Fmoc-L-leucin
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Leu-OH
  • Fmoc-L-leucine≥ 99.7% (HPLC, Chiral purity)
  • (2R)-2-amino-3-[4-[4-[(2R)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]phenyl]phenyl]propanoic acid
  • FMOC-LEU-OH 250 G
  • FMOC-LEU-OH 100 G
  • L-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
  • L-LEUCINE-N-FMOC
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoicaci
  • Fmoc-Leu-OH Fmoc-Leu-OH
  • FMOC-L-Leucine USP/EP/BP
  • Fmoc-L-leucine, puriss, 99%
  • N-(9-Fluorenylmethoxycarbonyl)-L-leucine Fmoc-L-leucine 2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-methylpentanoic acid N-Fmoc-L-leucine
  • (((9H-fluoren-9-yl)methoxy)carbonyl)-L-leucine
  • 35661-60-0
  • 35661-60-6
  • C21H323NO4
  • CH32CHCH2CHNHFMOCCOOH