ChemicalBook > CAS DataBase List > 1-Chloroisoquinoline

1-Chloroisoquinoline

Product Name
1-Chloroisoquinoline
CAS No.
19493-44-8
Chemical Name
1-Chloroisoquinoline
Synonyms
chloroisoquinoline;1-Chloroisoquinone;1-CHLOROISOQUINOLINE;Isoquinoline, 1-chloro-;1-Chloroisoquinoline,95%;1-Chloroisoquinoline 95%;1-Chloroisoquinoline >1-Chloroisoquinoline, 97+%;1-Chloroisoquinoline, 97+% 5GR;1-CHLOROISOQUINOLINE, 98.0+%(GC)
CBNumber
CB1362127
Molecular Formula
C9H6ClN
Formula Weight
163.6
MOL File
19493-44-8.mol
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1-Chloroisoquinoline Property

Melting point:
31-36 °C (lit.)
Boiling point:
274-275 °C/768 mmHg (lit.)
Density 
1.2108 (rough estimate)
refractive index 
1.6342 (estimate)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,2-8°C
form 
Low Melting Solid, Crystals and/or Chunks
pka
2.03±0.30(Predicted)
color 
White to yellow
Water Solubility 
Insoluble in water.
BRN 
2996
InChIKey
MSQCQINLJMEVNJ-UHFFFAOYSA-N
CAS DataBase Reference
19493-44-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29334900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
156744
Product name
1-Chloroisoquinoline
Purity
95%
Packaging
1g
Price
$25.44
Updated
2024/03/01
Sigma-Aldrich
Product number
156744
Product name
1-Chloroisoquinoline
Purity
95%
Packaging
5g
Price
$135
Updated
2023/06/20
TCI Chemical
Product number
C2097
Product name
1-Chloroisoquinoline
Purity
>98.0%(GC)
Packaging
5g
Price
$96
Updated
2024/03/01
TCI Chemical
Product number
C2097
Product name
1-Chloroisoquinoline
Purity
>98.0%(GC)
Packaging
25g
Price
$294
Updated
2024/03/01
Alfa Aesar
Product number
L17831
Product name
1-Chloroisoquinoline, 95%
Packaging
1g
Price
$38.65
Updated
2024/03/01
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1-Chloroisoquinoline Chemical Properties,Usage,Production

Chemical Properties

white to yellow low melting solid, crystals and/or

Uses

Used in a Mn-catalyzed cross-coupling with aryl- and alkylmagnesium halides.1 Also used in a Pd-catalyzed cross-coupling with heteroaryl boronic acids and esters.2

Uses

1-Chloroisoquinone is used in the preparation of new aminoisoquinolinylurea derivatives which show antiproliferative activity against melanoma cell lines. It can also be applied to the control of stor age and stability of unstable boronic acids.

Uses

The product has been used in a Mn-catalyzed cross-coupling with aryl- and alkylmagnesium halides. It has also been used in a Pd-catalyzed cross-coupling with heteroaryl boronic acids and esters. Furthermore, it has been used in a homocoupling reaction to yield bis-isoquinoline, each enantiomer of which might be very useful as a chiral ligand for asymmetric synthesis. 1-Chloroisoquinone is used in the preparation of new aminoisoquinolinylurea derivatives which show antiproliferative activity against melanoma cell lines. It can also be applied to the control of storage age and stability of unstable boronic acids.

1-Chloroisoquinoline Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Chloroisoquinoline Suppliers

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View Lastest Price from 1-Chloroisoquinoline manufacturers

Hebei Duling International Trade Co. LTD
Product
1-Chloroisoquinoline 19493-44-8
Price
US $20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 Ton
Release date
2023-03-09
R&D Scientific Inc.
Product
1-Chloroisoquinone 19493-44-8
Price
US $950.00/g
Min. Order
1g
Purity
97
Supply Ability
500 Kg
Release date
2024-02-19
Kindchem(Nanjing)Co.,Ltd
Product
1-Chloroisoquinoline 19493-44-8
Price
US $0.00-0.00/G
Min. Order
10G
Purity
0.98
Supply Ability
500kg
Release date
2024-01-05

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