ChemicalBook > CAS DataBase List > Hematoxylin

Hematoxylin

Product Name
Hematoxylin
CAS No.
517-28-2
Chemical Name
Hematoxylin
Synonyms
HEMATOXYLIN CERTIFIED;C.I.75290;nci-c55889;Nsc 270085;Color fine;bematoxylin;h(a)ematine;Homaeoxylin;Hematoxylin;hematoxyline
CBNumber
CB1382426
Molecular Formula
C16H14O6
Formula Weight
302.28
MOL File
517-28-2.mol
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Hematoxylin Property

Melting point:
200 °C (dec.)(lit.)
Boiling point:
363.32°C (rough estimate)
Density 
1.2514 (rough estimate)
vapor pressure 
0-0Pa at 20-25℃
refractive index 
1.4600 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Soluble in 95% ethanol(1 mg/mL).
Colour Index 
75290
pka
6.7(at 25℃)
form 
Powder/Solid
color 
Yellow to Brown
PH Range
Red (0.0) to yellow (1.0);Pale yellow (5.0) to violet (6.0)
Water Solubility 
SOLUBLE IN HOT WATER
Sensitive 
Light Sensitive
λmax
292nm, 445nm, 560nm
Merck 
14,4637
BRN 
91399
Stability:
Stable, but may discolour on exposure to light. Incompatible with strong oxidizing agents.
Major Application
Plasma displays, textiles, hair dyes, identifying fresh and stale rice, diag-nosing cancer progression, detecting nosing cancer progression, cervical disease, central nervous system malfunctions, detecting genes, breast cancer, collagen in a tissue sample, apoptosis, demyelinating diseases, antigens, treatment of age-related macular degeneration, burns, prostate cancer, diabetesand obesity, viral diseases, neoplasms, peripheral neural and vascular ailments, skin disorders, biotechnological applications, reference standard materials for cytology, histology andimmunohistochemistry
InChIKey
WZUVPPKBWHMQCE-UHFFFAOYSA-N
LogP
0.3 at 30℃ and pH6.9
CAS DataBase Reference
517-28-2
EPA Substance Registry System
Hematoxylin (517-28-2)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-36
WGK Germany 
2
RTECS 
MH7875000
TSCA 
Yes
HS Code 
32030019
Hazardous Substances Data
517-28-2(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1.04302
Product name
Hematoxylin cryst. (C.I. 75290)
Purity
for microscopy
Packaging
25g
Price
$213
Updated
2024/03/01
Sigma-Aldrich
Product number
1.04302
Product name
Hematoxylin cryst. (C.I. 75290)
Purity
for microscopy
Packaging
100g
Price
$604
Updated
2024/03/01
Sigma-Aldrich
Product number
1.04302
Product name
Hematoxylin cryst. (C.I. 75290)
Purity
for microscopy
Packaging
1kg
Price
$6710
Updated
2024/03/01
Sigma-Aldrich
Product number
234
Product name
Hematoxylin
Purity
HARLECO? Nuclear staining
Packaging
25g
Price
$122
Updated
2023/01/07
Sigma-Aldrich
Product number
234
Product name
Hematoxylin
Purity
HARLECO? Nuclear staining
Packaging
100g
Price
$424
Updated
2023/01/07
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Hematoxylin Chemical Properties,Usage,Production

Chemical Properties

light brown crystals or powder

Uses

Colorant in inks, biological stains.

Uses

Hematoxylin and eosin together make up Hematoxylin and eosin stain, one of the most commonly used stains in histology. Metal-haematein complexes are used to stain cell nuclei prior to examination under a microscope. Structures that stain with iron- or aluminum-haematein are often called basophilic, even though the mechanism of the staining is different from that of staining with basic dyes.

Definition

ChEBI: (+)-haematoxylin is a haematoxylin. It is an enantiomer of a (-)-haematoxylin.

General Description

White to yellowish crystals that redden on exposure to light.

Air & Water Reactions

Soluble in hot water, slightly water soluble in cold .

Reactivity Profile

Sensitive to light. .

Hazard

May be carcinogenic.

storage

Store at RT

Purification Methods

Hematoxylin recrystallises from H2O (as trihydrate) in white-yellow crystals which become red on exposure to light and then melt at 100-120o. It has been recrystallised from Me2CO/*C6H6. It has been recrystallised as well from dilute aqueous NaHSO3 until colourless and is soluble in alkali, borax and glycerol. Store it in the dark below 0o. [Morsingh & Robinson Tetrahedron 26 182 1970, Dann & Hofmann Chem Ber 98 1498 1955, Beilstein 17/8 V 469.]

Hematoxylin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Hematoxylin manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
Hematoxylin 517-28-2
Price
US $5.00/kg
Min. Order
1kg
Purity
99.912%
Supply Ability
10ton
Release date
2024-04-28
Changsha Staherb Natural Ingredients Co., Ltd.
Product
Hematoxylin 517-28-2
Price
US $0.00/KG
Min. Order
1KG
Purity
>99% HPLC
Supply Ability
1000KG
Release date
2022-09-22
Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
Hematoxylin 517-28-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99.91%
Supply Ability
200000
Release date
2024-04-25

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