ChemicalBook > CAS DataBase List > 2-Amino-2-phenylacetic acid

2-Amino-2-phenylacetic acid

Product Name
2-Amino-2-phenylacetic acid
CAS No.
2835-06-5
Chemical Name
2-Amino-2-phenylacetic acid
Synonyms
2-Phenylglycine;α-phenylglycine;DL-ALPHA-PHENYLGLYCINE;H-DL-PHG-OH;DL-PHENYLGLYCINE;DL-2-PHENYLGLYCINE;DL-α-Phenylglycine;2-Amino-2-phenyL;DL-A-PHENYLGLYCINE;RARECHEM AK ML 0501
CBNumber
CB1420201
Molecular Formula
C8H9NO2
Formula Weight
151.17
MOL File
2835-06-5.mol
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2-Amino-2-phenylacetic acid Property

Melting point:
290 °C (subl.)(lit.)
Boiling point:
273.17°C (rough estimate)
alpha 
[α]D20-0.5～+0.5゜ (c=5, dil. HCl)
Density 
1.2023 (rough estimate)
refractive index 
1.5810 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
almost transparency in Sodium hydroxide solution
pka
1.94±0.10(Predicted)
form 
Crystalline Powder
color 
White to off-white
Water Solubility 
115g/L(100 ºC)
Merck 
14,7291
BRN 
3197862
InChIKey
ZGUNAGUHMKGQNY-UHFFFAOYSA-N
CAS DataBase Reference
2835-06-5(CAS DataBase Reference)
NIST Chemistry Reference
Benzeneacetic acid, «alpha»-amino-, (.+/-.)-(2835-06-5)
EPA Substance Registry System
2-Phenylglycine (2835-06-5)
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Safety

Hazard Codes 
F,C
Risk Statements 
11-34
Safety Statements 
24/25-45-36/37/39-26-16
WGK Germany 
3
TSCA 
Yes
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P25507
Product name
2-Phenylglycine
Purity
95%
Packaging
100g
Price
$55.3
Updated
2024/03/01
TCI Chemical
Product number
P0326
Product name
DL-2-Phenylglycine
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$20
Updated
2024/03/01
TCI Chemical
Product number
P0326
Product name
DL-2-Phenylglycine
Purity
>98.0%(HPLC)(T)
Packaging
500g
Price
$234
Updated
2024/03/01
Alfa Aesar
Product number
B21129
Product name
DL-2-Phenylglycine, 98%
Packaging
25g
Price
$20.4
Updated
2021/12/16
Alfa Aesar
Product number
B21129
Product name
DL-2-Phenylglycine, 98%
Packaging
100g
Price
$35.9
Updated
2021/12/16
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2-Amino-2-phenylacetic acid Chemical Properties,Usage,Production

Description

2-Amino-2-phenylacetic acid is a natural compound that has been identified as a selective inhibitor of cyclooxygenase 2 (COX-2), and it exhibits antiinflammatory activity. It has been shown to inhibit COX-2 at low concentrations and to be less potent than aspirin in inhibiting COX-1. It is also an amide, with a molecular weight of 296. In order to determine the structure of it, XRD data was collected from the monosodium salt form of the compound. The ester hydrochloride form was used for enzyme activity assays because it is more soluble in water than the free base form. The synthesis of 2-Amino-2-phenylacetic acid was achieved through a two step process involving amide formation and hydrolysis.

Chemical Properties

white amorphous powder

Uses

DL-α-Phenylglycine is used as a reagent in the synthesis of benzoquinone-amino acid conjugates which have antibacterial activity.

Definition

ChEBI: An amino acid with a structure in which a phenyl ring is bonded to the alpha-carbon of glycine.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 3, p. 84, 1955
Synthetic Communications, 2, p. 423, 1972 DOI: 10.1080/00397917208081791

2-Amino-2-phenylacetic acid Preparation Products And Raw materials

Raw materials

4-Chlorobenzaldehyde Sodium cyanide Ammonium bicarbonate Glyoxylic acid

Preparation Products

1-Methyl-3-phenylpiperazine
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2-Amino-2-phenylacetic acid Suppliers

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View Lastest Price from 2-Amino-2-phenylacetic acid manufacturers

Hebei Guanlang Biotechnology Co., Ltd.
Product
2-Amino-2-phenylacetic acid 2835-06-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2023-01-11
WUHAN FORTUNA CHEMICAL CO., LTD
Product
DL-Phenylglycine 2835-06-5
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500kgs
Release date
2021-09-28
Hebei Mojin Biotechnology Co., Ltd
Product
2-Amino-2-phenylacetic acid 2835-06-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-15

2835-06-5, 2-Amino-2-phenylacetic acidRelated Search:

Aniline Diethylstilbestrol DL-Phenylalanine 4-Aminobenzoic acid 2-AMINOPHENYLACETIC ACID Triphenyltin acetate 4-Aminophenylacetic acid 4-Hydroxy-D-(-)-2-phenylglycine Sulfanilamide ALTRENOGEST Sulfanilic acid p-Anisidine 2-AMINOPHENYLACETIC ACID 3-Aminophenylacetic acid Glycine Iminodiacetic acid Nitrilotriacetic acid Anilinoacetic acid

  • RARECHEM AK ML 0501
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  • DL-ALPHA-PHENYLGLYCINE
  • DL-ALPHA-AMINOPHENYLACETIC ACID
  • DL-PHENYLGLYCINE
  • LABOTEST-BB LT00005726
  • H-DL-(PHENYL)GLY-OH
  • H-DL-PHG-OH
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