2-Amino-2-phenylacetic acid
- Product Name
- 2-Amino-2-phenylacetic acid
- CAS No.
- 2835-06-5
- Chemical Name
- 2-Amino-2-phenylacetic acid
- Synonyms
- 2-Phenylglycine;α-phenylglycine;DL-ALPHA-PHENYLGLYCINE;H-DL-PHG-OH;DL-PHENYLGLYCINE;DL-2-PHENYLGLYCINE;DL-α-Phenylglycine;2-Amino-2-phenyL;DL-A-PHENYLGLYCINE;RARECHEM AK ML 0501
- CBNumber
- CB1420201
- Molecular Formula
- C8H9NO2
- Formula Weight
- 151.17
- MOL File
- 2835-06-5.mol
2-Amino-2-phenylacetic acid Property
- Melting point:
- 290 °C (subl.)(lit.)
- Boiling point:
- 273.17°C (rough estimate)
- alpha
- [α]D20-0.5～+0.5゜ (c=5, dil. HCl)
- Density
- 1.2023 (rough estimate)
- refractive index
- 1.5810 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- almost transparency in Sodium hydroxide solution
- pka
- 1.94±0.10(Predicted)
- form
- Crystalline Powder
- color
- White to off-white
- Water Solubility
- 115g/L(100 ºC)
- Merck
- 14,7291
- BRN
- 3197862
- InChIKey
- ZGUNAGUHMKGQNY-UHFFFAOYSA-N
- CAS DataBase Reference
- 2835-06-5(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzeneacetic acid, «alpha»-amino-, (.+/-.)-(2835-06-5)
- EPA Substance Registry System
- 2-Phenylglycine (2835-06-5)
Safety
- Hazard Codes
- F,C
- Risk Statements
- 11-34
- Safety Statements
- 24/25-45-36/37/39-26-16
- WGK Germany
- 3
- TSCA
- Yes
- HS Code
- 29224999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P25507
- Product name
- 2-Phenylglycine
- Purity
- 95%
- Packaging
- 100g
- Price
- $55.3
- Updated
- 2024/03/01
- Product number
- P0326
- Product name
- DL-2-Phenylglycine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $20
- Updated
- 2024/03/01
- Product number
- P0326
- Product name
- DL-2-Phenylglycine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 500g
- Price
- $234
- Updated
- 2024/03/01
- Product number
- B21129
- Product name
- DL-2-Phenylglycine, 98%
- Packaging
- 25g
- Price
- $20.4
- Updated
- 2021/12/16
- Product number
- B21129
- Product name
- DL-2-Phenylglycine, 98%
- Packaging
- 100g
- Price
- $35.9
- Updated
- 2021/12/16
2-Amino-2-phenylacetic acid Chemical Properties,Usage,Production
Description
2-Amino-2-phenylacetic acid is a natural compound that has been identified as a selective inhibitor of cyclooxygenase 2 (COX-2), and it exhibits antiinflammatory activity. It has been shown to inhibit COX-2 at low concentrations and to be less potent than aspirin in inhibiting COX-1. It is also an amide, with a molecular weight of 296. In order to determine the structure of it, XRD data was collected from the monosodium salt form of the compound. The ester hydrochloride form was used for enzyme activity assays because it is more soluble in water than the free base form. The synthesis of 2-Amino-2-phenylacetic acid was achieved through a two step process involving amide formation and hydrolysis.
Chemical Properties
white amorphous powder
Uses
DL-α-Phenylglycine is used as a reagent in the synthesis of benzoquinone-amino acid conjugates which have antibacterial activity.
Definition
ChEBI: An amino acid with a structure in which a phenyl ring is bonded to the alpha-carbon of glycine.
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 3, p. 84, 1955
Synthetic Communications, 2, p. 423, 1972 DOI: 10.1080/00397917208081791
2-Amino-2-phenylacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-Amino-2-phenylacetic acid Suppliers
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View Lastest Price from 2-Amino-2-phenylacetic acid manufacturers
- Product
- DL-Phenylglycine 2835-06-5
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 500kgs
- Release date
- 2021-09-28
- Product
- 2-Amino-2-phenylacetic acid 2835-06-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2023-01-11
- Product
- 2-Amino-2-phenylacetic acid 2835-06-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-08-15