1-Adamantanemethanol
- Product Name
- 1-Adamantanemethanol
- CAS No.
- 770-71-8
- Chemical Name
- 1-Adamantanemethanol
- Synonyms
- AKOS BC-0668;1-amantadinol;Adamantanemethanol;1-Adamantlcarbinol;1-adamantanemethol;RARECHEM AQ TC 1004;CHEMBRDG-BB 4013930;1-ADAMANTYLMETHANOL;1-Adamantylcarbinol;1-ADAMANTANEMETHANOL
- CBNumber
- CB1448137
- Molecular Formula
- C11H18O
- Formula Weight
- 166.26
- MOL File
- 770-71-8.mol
1-Adamantanemethanol Property
- Melting point:
- 114-117 °C (lit.)
- Boiling point:
- 234.5°C (rough estimate)
- Density
- 0.8802 (rough estimate)
- refractive index
- 1.5000 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 15.51±0.10(Predicted)
- form
- Crystalline Powder
- color
- White
- Water Solubility
- Insoluble in water. Solubility in methanol (almost transparency).
- BRN
- 1853339
- InChI
- InChI=1S/C11H18O/c12-7-11-4-8-1-9(5-11)3-10(2-8)6-11/h8-10,12H,1-7H2
- InChIKey
- MDVGOOIANLZFCP-UHFFFAOYSA-N
- SMILES
- C12(CO)CC3CC(CC(C3)C1)C2
- CAS DataBase Reference
- 770-71-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-24/25-36-26
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29061900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H0420
- Product name
- 1-Adamantanemethanol
- Purity
- >99.0%(GC)
- Packaging
- 1g
- Price
- $20
- Updated
- 2024/03/01
- Product number
- H0420
- Product name
- 1-Adamantanemethanol
- Purity
- >99.0%(GC)
- Packaging
- 5g
- Price
- $56
- Updated
- 2024/03/01
- Product number
- B23831
- Product name
- 1-Adamantanemethanol, 98%
- Packaging
- 5g
- Price
- $51.65
- Updated
- 2024/03/01
- Product number
- B23831
- Product name
- 1-Adamantanemethanol, 98%
- Packaging
- 1g
- Price
- $17.1
- Updated
- 2022/04/27
- Product number
- H0420
- Product name
- 1-Adamantanemethanol
- Purity
- >99.0%(GC)
- Packaging
- 25g
- Price
- $92
- Updated
- 2024/03/01
1-Adamantanemethanol Chemical Properties,Usage,Production
Description
1-Adamantanemethanol acts as guest molecule and forms β-cyclodextrin complexes. It reacts with 3,4,5,6-tetrafluorophthalonitrile to yield 3,4,5,6-tetra-(1-adamantylmethoxy)phthalonitrile.
Chemical Properties
white crystalline powder
Uses
1-Adamantanemethanol was used in the synthesis of axially disubstituted silicon(IV) phthalocyanines. It is used as a reagent in the synthesis of adamantane and noradamantane based histone deacetylase (HDAC) inhibitors for the treatment of cancer. It is also used as a reagent in the synthesis of (1-adamantyl)methyl glycidyl ether, a versatile building block for living polymerization.
References
Gopalan, B., et al.: Bioorg. Med. Chem. Lett., 23, 2532 (2013);
Suzuki, T., et al.: J. Med. Chem., 55, 9562 (2012);
Moers, C., et al.: Macromol. Rapid Comm., 35, 1075 (2014)
Purification Methods
Dissolve the adamantane in Et2O, wash it with aqueous 0.1N NaOH and H2O, dry over CaCl2, evaporate and recrystallise the residue from aqueous MeOH. [Stetter et al. Chem Ber 92 1629 1959, Beilstein 6 IV 400.]
1-Adamantanemethanol Preparation Products And Raw materials
Raw materials
Preparation Products
1-Adamantanemethanol Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28398
- Advantage
- 80
View Lastest Price from 1-Adamantanemethanol manufacturers
- Product
- 1-Adamantane Methanol 770-71-8
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99.6%
- Supply Ability
- 100000
- Release date
- 2024-04-24
- Product
- 1-Adamantanemethanol 770-71-8
- Price
- US $37.00-33.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 1000kg
- Release date
- 2023-01-06
- Product
- 1-Adamantane Methanol 770-71-8
- Price
- US $100.00/bag
- Min. Order
- 1bag
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2023-08-23