2-CHLOROQUINOLINE-3-CARBALDEHYDE

Product Name: 2-CHLOROQUINOLINE-3-CARBALDEHYDE
CAS No.: 73568-25-9
Chemical Name: 2-CHLOROQUINOLINE-3-CARBALDEHYDE
Synonyms: SBB000302;ZINC00061503;AKOS AU36-M569;390119_ALDRICH;ASISCHEM C51996;AKOS BBS-00001118;RARECHEM AK ML 0551;TIMTEC-BB SBB000302;IFLAB-BB F0010-0600;2-Chloro-3-formylquinoline
CBNumber: CB1451393
Molecular Formula: C10H6ClNO
Formula Weight: 191.61
MOL File: 73568-25-9.mol

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2-CHLOROQUINOLINE-3-CARBALDEHYDE Property

Melting point:: 148-150 °C (lit.)
Boiling point:: 335.8±22.0 °C(Predicted)
Density: 1.364
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
pka: -1.31±0.50(Predicted)
form: Liquid
color: Clear colorless to yellow
Sensitive: Air Sensitive
InChIKey: SDKQWXCBSNMYBN-UHFFFAOYSA-N
CAS DataBase Reference: 73568-25-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3
HS Code: 29334900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 390119
Product name: 2-Chloro-3-quinolinecarboxaldehyde
Purity: 98%
Packaging: 1g
Price: $33
Updated: 2023/01/07

Sigma-Aldrich

Product number: 390119
Product name: 2-Chloro-3-quinolinecarboxaldehyde
Purity: 98%
Packaging: 10g
Price: $165
Updated: 2023/01/07

TCI Chemical

Product number: C2289
Product name: 2-Chloro-3-quinolinecarboxaldehyde
Purity: >98.0%(GC)
Packaging: 1g
Price: $20
Updated: 2025/07/31

TCI Chemical

Product number: C2289
Product name: 2-Chloro-3-quinolinecarboxaldehyde
Purity: >98.0%(GC)
Packaging: 5g
Price: $59
Updated: 2025/07/31

TRC

Product number: C381378
Product name: 2-Chloroquinoline-3-carbaldehyde
Packaging: 100mg
Price: $60
Updated: 2021/12/16

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2-CHLOROQUINOLINE-3-CARBALDEHYDE Chemical Properties,Usage,Production

Chemical Properties

Yellow to yellow-brown crystalline powder

Synthesis

612-62-4

73568-25-9

Example 7 Synthesis of 2-chloro-3-quinolinecarboxaldehyde: 1.53 mL (3.30 mmol) of n-butyllithium (n-BuLi) was added slowly and dropwise to an 8 mL THF solution containing 0.46 mL (3.30 mmol) of diisopropylamine at 0 °C. After 20 minutes of reaction, the solution was cooled to -78 °C and 2-chloroquinoline (491 mg, 3.0 mmol) was added at this temperature. The mixture was stirred at -78 °C for 30 min, followed by dropwise addition of dimethylformamide (0.39 mL, 5.04 mmol) and continued stirring at the same temperature for 30 min. Upon completion of the reaction, the reaction was quenched with glacial acetic acid (1 mL) at -78 °C, then the mixture was slowly warmed to room temperature and diluted with ether (30 mL). The organic phase was washed sequentially with saturated NaHCO3 solution (10 mL) and brine (10 mL) and dried over anhydrous MgSO4. Concentration gave 2-chloro-3-quinolinecarboxaldehyde (530 mg, 92% yield) as a light yellow solid with melting point 145-149 °C, which could be used in the next reaction without further purification. By recrystallization from ethyl acetate, a pure product was obtained as pale yellow acicular crystals with a melting point of 149-150 °C (literature values 148-149 °C, see Meth-Cohn, O.; Narhe, B.; Tarnowski, B. J. Chem. Soc. Perkin Trans. I 1981, 1520).1H NMR (300 MHz, CDCl3) δ 10.57 (s, 1H), 8.77 (s, 1H), 8.08 (d, 1H, J = 9 Hz), 8.0 (d, 1H, J = 9 Hz), 7.90 (t, 1H, J = 9 Hz), 7.67 (t, 1H, J = 9 Hz); IR (nujol) 1685, 1575, 1045, 760, 745 cm-1. 745 cm-1.

References

[1] Patent: US5212317, 1993, A
[2] Patent: US5162532, 1992, A

2-CHLOROQUINOLINE-3-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CHLOROQUINOLINE-3-CARBALDEHYDE Suppliers

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View Lastest Price from 2-CHLOROQUINOLINE-3-CARBALDEHYDE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-CHLOROQUINOLINE-3-CARBALDEHYDE 73568-25-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-30

Hebei Chuanghai Biotechnology Co,.LTD

Product: 2-CHLOROQUINOLINE-3-CARBALDEHYDE 73568-25-9
Price: US $30.00-10.00/kg
Min. Order: 10kg
Purity: 99%
Supply Ability: 100000kg
Release date: 2024-08-23

Hebei Zhanyao Biotechnology Co. Ltd

Product: 2-CHLOROQUINOLINE-3-CARBALDEHYDE 73568-25-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 tons
Release date: 2021-10-13

73568-25-9, 2-CHLOROQUINOLINE-3-CARBALDEHYDERelated Search:

2-Chloro-6-methyl-3-quinolinecarbaldehyde 2-CHLORO-6-METHOXYQUINOLINE-3-CARBALDEHYDE 2-CHLOROQUINOLINE-3-CARBALDEHYDE 3-Quinolinecarboxaldehyde 2-Chloroquinoline 2-CHLORO-6-(ETHYLOXY)QUINOLINE-3-CARBALDEHYDE 2-CHLORO-6,7-DIMETHOXY-QUINOLINE-3-CARBALDEHYDE 2,4-DICHLOROQUINOLIN-3-CARBOXALDEHYDE 2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE 2-CHLORO-5,6,7-TRIMETHOXY-QUINOLINE-3-CARBALDEHYDE 2,4-Dichloro-quinoline-3-carboxylic acid ethyl ester 6-CHLORO-[1,3]DIOXOLO[4,5-G]QUINOLINE-7-CARBALDEHYDE 2-CHLORO-7-METHYL-3-QUINOLINECARBOXALDEHYDE 2-CHLORO-7-ETHOXY-3-QUINOLINECARBALDEHYDE 2-CHLORO-7,8-DIMETHYL-3-QUINOLINECARBALDEHYDE 2-CHLORO-7-METHYLSULFANYL-QUINOLINE-3-CARBALDEHYDE 2-CHLORO-6-ETHYLQUINOLINE-3-CARBALDEHYDE 2-CHLOROQUINOLINE-6-CARBALDEHYDE

TIMTEC-BB SBB000302

RARECHEM AK ML 0551

2-CHLOROQUINOLINE-3-CARBALDEHYDE

2-CHLOROQUINOLINE-3-CARBOXALDEHYDE

2-CHLORO-3-QUINOLINECARBOXALDEHYDE

ASISCHEM C51996

IFLAB-BB F0010-0600

AKOS AU36-M569

AKOS BBS-00001118

2-Chloro-3-formylquinoline

2-Chloro-3-quinolinecarbaldehyde

2-Chloro-3-quinolinecarboxaldehyde,98%

2-Chloro-3-quinolinecarboxaldehyde 98%

390119_ALDRICH

SBB000302

ZINC00061503

JRH-03801, 2-Chloroquinoline-3-carbaldehyde, 97%

2-Chloro-3-quinolinecarboxaldehyde &gt

3-Quinolinecarboxaldehyde, 2-chloro-

2-CHLOROQUINOLINE-3-CARBALDEHYDE ISO 9001：2015 REACH

73568-25-9

73568-28-9

C10H6NOCl

C10H6ClNO

ARYL ALDEHYDE

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