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ACACETIN-7-GLUCOSIDE

Product Name
ACACETIN-7-GLUCOSIDE
CAS No.
4291-60-5
Chemical Name
ACACETIN-7-GLUCOSIDE
Synonyms
TILIANIN;Astroside;cirsioside;leptomerine;Moldavoside;ACACETIN-7-GLUCOSIDE;Acacetin 7-O-glucoside;Tilianin, 10 mM in DMSO;ACACETIN-7-GLUCOSIDE USP/EP/BP;Apigenin-7-O-beta-D-glucopyranoside-4'-O-methyl ether
CBNumber
CB1454501
Molecular Formula
C22H22O10
Formula Weight
446.4
MOL File
4291-60-5.mol
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ACACETIN-7-GLUCOSIDE Property

Melting point:
260-262℃
Boiling point:
754.9±60.0 °C(Predicted)
Density 
1.545±0.06 g/cm3(Predicted)
solubility 
Soluble in DMSO
form 
powder
pka
6.11±0.40(Predicted)
color 
White-yellowish
InChI
1S/C22H22O10/c1-29-11-4-2-10(3-5-11)15-8-14(25)18-13(24)6-12(7-16(18)31-15)30-22-21(28)20(27)19(26)17(9-23)32-22/h2-8,17,19-24,26-28H,9H2,1H3
InChIKey
NLZCOTZRUWYPTP-KWEUGPCZNA-N
SMILES
C1(C2=CC=C(OC)C=C2)OC2=C(C(=CC(OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C2)O)C(=O)C=1 |&1:18,21,23,25,r|
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Safety

WGK Germany 
WGK 3
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FT137887
Product name
Tilianin
Packaging
1mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FT137887
Product name
Tilianin
Packaging
2mg
Price
$160
Updated
2021/12/16
ChemScene
Product number
CS-0022827
Product name
Tilianin
Purity
99.57%
Packaging
5mg
Price
$202
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594557
Product name
Tilianin
Packaging
10mg
Price
$391
Updated
2021/12/16
Biosynth Carbosynth
Product number
FT137887
Product name
Tilianin
Packaging
10mg
Price
$400
Updated
2021/12/16
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ACACETIN-7-GLUCOSIDE Chemical Properties,Usage,Production

Chemical Properties

Soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Dracocephalum moldavica L.

Uses

Tilianin has lipid-lowering and anti-inflammatory effects.

Biological Activity

Tilianin is an active flavonoid glycoside, widely present in a variety of medicinal plants, with antihypertensive, myocardial protection, antidiabetic, hypolipidemic, anti-inflammatory, antioxidant and other effects.

Synthesis

Since the chemical constituents of Fragrant Green Orchid Seed (Seed) have not been reported in the literature, the present study was carried out to isolate the chemical constituents from the authentic Fragrant Green Orchid Seed identified. The powder of Fragrant Green Orchid Seed was extracted by refluxing 10 times amount of 70% ethanol for 3h for three times. The ethanol was recovered, and the aqueous layer was extracted by adding 2 times the volume of dichloromethane for 6 times, and the dichloromethane layers were combined. After recovering the organic solvent, the extract was wet loaded onto a silica gel column, and rinsed with petroleum ether, petroleum ether-ethyl acetate (100:1, 50:1, 20:1, 10:1, 5:1, 1:1), and ethyl acetate, respectively, and the stream fractions were collected, and the collector of each time was also concentrated for the high performance liquid chromatography (HPLC) analysis and the thin-layer The collected fractions were collected, and at the same time, each collection was concentrated and analyzed by high performance liquid chromatography and thin-layer tracking analysis, from which field thistle glycosides (vanilloid glycosides) were isolated.

in vitro

Tilianin (10 μM, 20 μM) reduced secretion of LPS (1 μg/mL)-induced proinflammatory cytokine in RAW264.7 macrophage cell.

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target

5-HT Receptor | GABA Receptor | ATPase | NO | NOS | Caspase | Bcl-2/Bax | Potassium Channel | P-gp

ACACETIN-7-GLUCOSIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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ACACETIN-7-GLUCOSIDE Suppliers

China 118 United Kingdom 2 United States 6 Global 126
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+86-27-84254680
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aileen@chemfaces.com
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China
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View Lastest Price from ACACETIN-7-GLUCOSIDE manufacturers

Career Henan Chemical Co
Product
ACACETIN-7-GLUCOSIDE 4291-60-5
Price
US $9.80/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2020-01-09

4291-60-5, ACACETIN-7-GLUCOSIDERelated Search:

hydroxygenkwanin beta-Eudesmol (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one (+)-Rabdosiin DiosMetin 7-O-β-D-Glucuronide 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one alpha-Terpineol Hydroxyecdysone alpha-Cyperone MOSLOFLAVONE Artemether beta-Sitosterol Typhaneoside Acacetin

  • ACACETIN-7-GLUCOSIDE
  • 7-(β-D-Glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
  • Acacetin 7-O-glucoside
  • Apigenin-7-O-beta-D-glucopyranoside-4'-O-methyl ether
  • Astroside
  • Moldavoside
  • leptomerine
  • TILIANIN
  • 4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-
  • ACACETIN-7-GLUCOSIDE USP/EP/BP
  • 5-Hydroxy-2-(4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
  • cirsioside
  • Tilianin, 10 mM in DMSO
  • 4291-60-5