ZM 306416 hydrochloride

Product Name: ZM 306416 hydrochloride
CAS No.: 196603-47-1
Chemical Name: ZM 306416 hydrochloride
Synonyms: ZM-306416 HCI;ZM306416 hydrochloride, VEGFR1/2 tyrosine kinase activity inhibitor;N-(4-Chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride
CBNumber: CB14718670
Molecular Formula: C16H14Cl2FN3O2
Formula Weight: 370.21
MOL File: 196603-47-1.mol

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ZM 306416 hydrochloride Property

storage temp.: RT
solubility: Soluble in DMSO (up to 5 mg/ml).
form: solid
color: White
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: Z486583
Product name: ZM-306416 hydrochloride
Packaging: 1mg
Price: $100
Updated: 2021/12/16

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ZM 306416 hydrochloride Chemical Properties,Usage,Production

Description

ZM-306416 (196603-47-1) is a VEGF receptor tyrosine kinase inhibitor with selectivity over FGFR-1 (KDR IC50 = 100 nM; FLT IC50 = 2 μM).

Uses

ZM 306416 Hydrochloride, is an inhibitor of tyrosine kinase RTK signaling pathway involved in anti-cancer agents. Anti-tumor, anti-metastatic agent.

IC 50

KDR: 100 nM (IC₅₀); Flt-1: 2000 nM (IC₅₀)

References

[1] LAURENT F. HENNEQUIN. Design and Structure−Activity Relationship of a New Class of Potent VEGF Receptor Tyrosine Kinase Inhibitors[J]. Journal of Medicinal Chemistry, 1999, 42 26: 5369-5389. DOI:10.1021/jm990345w

ZM 306416 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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ZM 306416 hydrochloride Suppliers

China 13 United Kingdom 1 United States 3 USA 1 Global 18

Shanghai YuanYe Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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196603-47-1, ZM 306416 hydrochlorideRelated Search:

A-83-01 PD 153035 HYDROCHLORIDE GW441756 (E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide ZM 306416 ZM 241385 ZM 39923 HCl ZM 336372 ZM 447439

ZM-306416 HCI

N-(4-Chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride

ZM306416 hydrochloride, VEGFR1/2 tyrosine kinase activity inhibitor

196603-47-1