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ZM 306416 hydrochloride

Product Name
ZM 306416 hydrochloride
CAS No.
196603-47-1
Chemical Name
ZM 306416 hydrochloride
Synonyms
ZM-306416 HCI;ZM306416 hydrochloride, VEGFR1/2 tyrosine kinase activity inhibitor;N-(4-Chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride
CBNumber
CB14718670
Molecular Formula
C16H14Cl2FN3O2
Formula Weight
370.21
MOL File
196603-47-1.mol
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ZM 306416 hydrochloride Property

storage temp. 
RT
solubility 
Soluble in DMSO (up to 5 mg/ml).
form 
solid
color 
White
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
Z486583
Product name
ZM-306416 hydrochloride
Packaging
1mg
Price
$100
Updated
2021/12/16
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ZM 306416 hydrochloride Chemical Properties,Usage,Production

Description

ZM-306416 (196603-47-1) is a VEGF receptor tyrosine kinase inhibitor with selectivity over FGFR-1 (KDR IC50 = 100 nM; FLT IC50 = 2 μM).

Uses

ZM 306416 Hydrochloride, is an inhibitor of tyrosine kinase RTK signaling pathway involved in anti-cancer agents. Anti-tumor, anti-metastatic agent.

IC 50

KDR: 100 nM (IC50); Flt-1: 2000 nM (IC50)

References

[1] LAURENT F. HENNEQUIN. Design and Structure−Activity Relationship of a New Class of Potent VEGF Receptor Tyrosine Kinase Inhibitors[J]. Journal of Medicinal Chemistry, 1999, 42 26: 5369-5389. DOI:10.1021/jm990345w

ZM 306416 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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ZM 306416 hydrochloride Suppliers

China 13 United Kingdom 1 United States 3 USA 1 Global 18
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
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QQ:3008007432
Email
3008007409@qq.com
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China
ProdList
71826
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Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
Fax
+86-21-51601218
Email
chaolaichem@foxmail.com
Country
China
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12476
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58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
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58
Jinan Jiuli Biotechnology Co. , Ltd.
Tel
15865264761
Email
486064515@qq.com
Country
China
ProdList
4810
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58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
59936
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58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
400-6206333 13167063860
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
48457
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58
Hubei wei shi reagent group ltd., company
Tel
027-59101766 13125137661
Email
2853877621@qq.com
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China
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7976
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TargetMol Chemicals Inc.
Tel
15002134094
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marketing@targetmol.cn
Country
China
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29423
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Shaoguan Qicheng Biotechnology Co., Ltd
Tel
18122215013
Email
780229652@qq.com
Country
China
ProdList
1292
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58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
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6051
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58

196603-47-1, ZM 306416 hydrochlorideRelated Search:

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  • ZM-306416 HCI
  • N-(4-Chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride
  • ZM306416 hydrochloride, VEGFR1/2 tyrosine kinase activity inhibitor
  • 196603-47-1