6-HYDROXY-7-METHOXYCOUMARIN
- Product Name
- 6-HYDROXY-7-METHOXYCOUMARIN
- CAS No.
- 776-86-3
- Chemical Name
- 6-HYDROXY-7-METHOXYCOUMARIN
- Synonyms
- ISOSCOPOLETIN;ISOSCOPOLETINE;Isoscopolamine;7-Methoxyesculetin;6-O-Demethylscoparone;esculetin 7-methyl ether;6-HYDROXY-7-METHYLCOUMARIN;6-HYDROXY-7-METHOXYCOUMARIN;7-METHOXY-6-HYDROXYCOUMARIN;6-hudroxy-7-methoxycoumarin
- CBNumber
- CB1472785
- Molecular Formula
- C10H8O4
- Formula Weight
- 192.17
- MOL File
- 776-86-3.mol
6-HYDROXY-7-METHOXYCOUMARIN Property
- Melting point:
- 206-208°C
- Boiling point:
- 413.5±45.0 °C(Predicted)
- Density
- 1.37 g/cm3
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO: soluble
- pka
- 8.94±0.20(Predicted)
- form
- Solid
- color
- Pale Beige to Light Beige
- LogP
- 0.830 (est)
- CAS DataBase Reference
- 776-86-3
Safety
- Hazard Codes
- Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 22-24/25-36-26
- WGK Germany
- 3
- F
- 8
- HS Code
- 29322090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- PHL85752
- Product name
- Isoscopoletin
- Purity
- phyproof? Reference Substance
- Packaging
- 20MG
- Price
- $344
- Updated
- 2024/03/01
- Product number
- H517345
- Product name
- 6-Hydroxy-7-methoxycoumarin
- Packaging
- 2.5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FI67110
- Product name
- Isoscopoletin
- Packaging
- 100mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- FI67110
- Product name
- Isoscopoletin
- Packaging
- 10mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FI67110
- Product name
- Isoscopoletin
- Packaging
- 25mg
- Price
- $75
- Updated
- 2021/12/16
6-HYDROXY-7-METHOXYCOUMARIN Chemical Properties,Usage,Production
Description
Isoscopolamine is an antiasthmatic drug, which has the effect of relaxing smooth muscle and antihistamine. It can be used clinically in patients with chronic bronchitis and bronchial asthma.
Chemical Properties
Yellow needle-like crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from Dengzhanhua, Rhododendron.
Uses
Isoscopolamine has anti-inflammatory, antioxidant, improving myocardial ischemia, anti-arrhythmic effects.
Definition
ChEBI: Isoscopoletin is a hydroxycoumarin that is esculetin in which the hydroxy group at position 7 is replaced by a methoxy group. It is the major primary metabolite of scoparone. It has a role as a plant metabolite. It is a hydroxycoumarin and an aromatic ether. It is functionally related to an esculetin.
Biological Activity
Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active ingredient in Artemisia argyi. It has a significant inhibitory effect on cell proliferation with IC50 values of 4.0 μM and 1.6 μM against human CCRF-CEM leukemia cells and drug-resistant subline CEM/ADR5000, respectively. It (6-Hydroxy-7-methoxycoumarin) has the activity of inhibiting HBV replication.
6-HYDROXY-7-METHOXYCOUMARIN Preparation Products And Raw materials
Raw materials
Preparation Products
6-HYDROXY-7-METHOXYCOUMARIN Suppliers
- Tel
- --
- Fax
- --
- info@specs.net
- Country
- The Netherlands
- ProdList
- 6833
- Advantage
- 70
View Lastest Price from 6-HYDROXY-7-METHOXYCOUMARIN manufacturers
- Product
- Isoscopoletin 776-86-3
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-09-27
- Product
- 6-HYDROXY-7-METHOXYCOUMARIN 776-86-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-05-28
- Product
- 6-HYDROXY-7-METHOXYCOUMARIN 776-86-3
- Price
- US $1.00/kg
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-24