IsochaMaejasMin

Product Name: IsochaMaejasMin
CAS No.: 93859-63-3
Chemical Name: IsochaMaejasMin
Synonyms: IsochaMaejasMin;Isochamaejasmine;(2R,2'S,3S,3'R)-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-[3,3'-bichroman]-4,4'-dione;(2R,2'S,3S,3'R)-rel-2,2',3,3'-Tetrahydro-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-[3,3'-bi-4H-1-benzopyran]-4,4'-dione;[3,3'-Bi-4H-1-benzopyran]-4,4'-dione, 2,2',3,3'-tetrahydro-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-, (2R,2'S,3S,3'R)-rel-
CBNumber: CB92654626
Molecular Formula: C30H22O10
Formula Weight: 542.49
MOL File: 93859-63-3.mol

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IsochaMaejasMin Property

Boiling point:: 932.6±65.0 °C(Predicted)
Density: 1.594±0.06 g/cm3(Predicted)
pka: 7.14±0.60(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

CSNpharm

Product number: CSN14611
Product name: Isochamaejasmine
Packaging: 1mg
Price: $370
Updated: 2021/12/16

Arctom

Product number: AS014687
Product name: Isochamaejasmine
Packaging: 5mg
Price: $371
Updated: 2021/12/16

Arctom

Product number: CFN92150
Product name: Isochamaejasmine
Purity: ≥98%
Packaging: 5mg
Price: $418
Updated: 2021/12/16

Crysdot

Product number: CD32000095
Product name: Isochamaejasmin
Purity: 95+%
Packaging: 5mg
Price: $810
Updated: 2021/12/16

CSNpharm

Product number: CSN14611
Product name: Isochamaejasmine
Packaging: 5mg
Price: $925
Updated: 2021/12/16

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IsochaMaejasMin Chemical Properties,Usage,Production

Uses

Isochamaejasmin is a biflavonoid with anti-cancer, antiplasmodial and insecticidal activities. Isochamaejasmin displays a potent NF-κB (NF-κB) activation activity. Isochamaejasmin could cause DNA damage and induce apoptosis via the mitochondrial pathway in AW1 cells[1][2]. Isochamaejasmin also has a moderate antiplasmodial activity (IC50 of 7.3 μM for P. falciparum) and relatively low cytotoxicity (CC50 of 29.0 μM)[3].

Definition

ChEBI: A biflavonoid that consists of two units of 5,7,4'-trihydroxyflavanone joined together at position 3 and 3''.

References

[1] Yuanhang Ren, et al. Isochamaejasmin induces toxic effects on Helicoverpa zea via DNA damage and mitochondria-associated apoptosis. Pest Manag Sci. 2021 Jan;77(1):557-567. DOI:10.1002/ps.6055
[2] Qinghai Tian, et al. Stereospecific induction of nuclear factor-kappaB activation by isochamaejasmin. Mol Pharmacol. 2005 Dec;68(6):1534-42. DOI:10.1124/mol.105.014720
[3] Liene Dhooghe, et al. Antiplasmodial activity of (I-3,II-3)-biflavonoids and other constituents from Ormocarpum kirkii. Phytochemistry. 2010 May;71(7):785-91. DOI:10.1016/j.phytochem.2010.02.005

IsochaMaejasMin Preparation Products And Raw materials

Raw materials

Preparation Products

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IsochaMaejasMin Suppliers

China 45 United States 5 Global 50

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93859-63-3, IsochaMaejasMinRelated Search:

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IsochaMaejasMin

(2R,2'S,3S,3'R)-rel-2,2',3,3'-Tetrahydro-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-[3,3'-bi-4H-1-benzopyran]-4,4'-dione

Isochamaejasmine

[3,3'-Bi-4H-1-benzopyran]-4,4'-dione, 2,2',3,3'-tetrahydro-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-, (2R,2'S,3S,3'R)-rel-

(2R,2'S,3S,3'R)-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-[3,3'-bichroman]-4,4'-dione

93859-63-3