6-HYDROXY-7-METHOXYCOUMARIN

Product Name: 6-HYDROXY-7-METHOXYCOUMARIN
CAS No.: 776-86-3
Chemical Name: 6-HYDROXY-7-METHOXYCOUMARIN
Synonyms: ISOSCOPOLETIN;ISOSCOPOLETINE;Isoscopolamine;7-Methoxyesculetin;6-O-Demethylscoparone;esculetin 7-methyl ether;6-HYDROXY-7-METHYLCOUMARIN;6-HYDROXY-7-METHOXYCOUMARIN;7-METHOXY-6-HYDROXYCOUMARIN;6-hudroxy-7-methoxycoumarin
CBNumber: CB1472785
Molecular Formula: C10H8O4
Formula Weight: 192.17
MOL File: 776-86-3.mol

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6-HYDROXY-7-METHOXYCOUMARIN Property

Melting point:: 206-208°C
Boiling point:: 413.5±45.0 °C(Predicted)
Density: 1.37 g/cm3
storage temp.: Sealed in dry,2-8°C
solubility: DMSO: soluble
pka: 8.94±0.20(Predicted)
form: Solid
color: Pale Beige to Light Beige
LogP: 0.830 (est)
CAS DataBase Reference: 776-86-3

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Safety

Hazard Codes: Xi
Risk Statements: 22-36/37/38
Safety Statements: 22-24/25-36-26
WGK Germany: 3
F: 8
HS Code: 29322090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL85752
Product name: Isoscopoletin
Purity: phyproof? Reference Substance
Packaging: 20MG
Price: $344
Updated: 2024/03/01

TRC

Product number: H517345
Product name: 6-Hydroxy-7-methoxycoumarin
Packaging: 2.5mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FI67110
Product name: Isoscopoletin
Packaging: 10mg
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FI67110
Product name: Isoscopoletin
Packaging: 25mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FI67110
Product name: Isoscopoletin
Packaging: 50mg
Price: $100
Updated: 2021/12/16

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6-HYDROXY-7-METHOXYCOUMARIN Chemical Properties,Usage,Production

Description

Isoscopolamine is an antiasthmatic drug, which has the effect of relaxing smooth muscle and antihistamine. It can be used clinically in patients with chronic bronchitis and bronchial asthma.

Chemical Properties

Yellow needle-like crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from Dengzhanhua, Rhododendron.

Uses

Isoscopolamine has anti-inflammatory, antioxidant, improving myocardial ischemia, anti-arrhythmic effects.

Definition

ChEBI: Isoscopoletin is a hydroxycoumarin that is esculetin in which the hydroxy group at position 7 is replaced by a methoxy group. It is the major primary metabolite of scoparone. It has a role as a plant metabolite. It is a hydroxycoumarin and an aromatic ether. It is functionally related to an esculetin.

Biological Activity

Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active ingredient in Artemisia argyi. It has a significant inhibitory effect on cell proliferation with IC50 values of 4.0 μM and 1.6 μM against human CCRF-CEM leukemia cells and drug-resistant subline CEM/ADR5000, respectively. It (6-Hydroxy-7-methoxycoumarin) has the activity of inhibiting HBV replication.

6-HYDROXY-7-METHOXYCOUMARIN Preparation Products And Raw materials

Raw materials

Isovanillin Acetic anhydride Sodium acetate trihydrate Ammonium persulfate Ethyl acetate PETROLEUM ETHER

Preparation Products

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6-HYDROXY-7-METHOXYCOUMARIN Suppliers

China 130 France 3 Germany 2 India 3 Switzerland 1 The Netherlands 1 United Kingdom 8 United States 18 USA 1 Global 167

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View Lastest Price from 6-HYDROXY-7-METHOXYCOUMARIN manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Isoscopoletin 776-86-3
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-09-27

Dideu Industries Group Limited

Product: 6-HYDROXY-7-METHOXYCOUMARIN 776-86-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-05-28

Career Henan Chemical Co

Product: 6-HYDROXY-7-METHOXYCOUMARIN 776-86-3
Price: US $1.00/kg
Min. Order: 1g
Purity: 99%
Supply Ability: 100KG
Release date: 2018-12-24

776-86-3, 6-HYDROXY-7-METHOXYCOUMARINRelated Search:

Isoengelitin Fluorescein isothiocyanate isomer I Isocarapanaubine (3β,20α)-17α-Hydroxyyohimban-16β-carboxylic acid methyl ester Iso Altenuene ISOPULEGOL, TECH. 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxy-2-methoxyphenyl)-8-[5-methyl-2-(1-methylvinyl)-4-hexenyl]-4H-1-benzopyran-4-one Isocoronarin D IsoMangiferolic acid 2″-O-α-L-Rhamnopyranosyl-isovitexin H-ILE-TYR-OH Isosalicifolin 5-PROPENYL-1,2,3-TRIMETHOXY Isoeleutherin ISOVITEXIN Isodunnial IsochaMaejasMin ISOQUERCITRIN

7-METHOXY-6-HYDROXYCOUMARIN

6-HYDROXY-7-METHYLCOUMARIN

6-HYDROXY-7-METHOXYCOUMARIN

ISOSCOPOLETIN

ISOSCOPOLETINE

6-hydroxy-7-methoxy-2-benzopyrone

6-Hydroxy-7-methyl coumarin-(Isoscopoletin) -

ISOSCOPOLETIN (6-HYDROXY-7-METHYLCOUMARIN)

7-Methoxyesculetin, Esculetin 7-methyl ether, Isoscopoletin

6-Hydroxy-7-methoxy-2H-1-benzopyran-2-one

6-O-Demethylscoparone

6-hydroxy-7-methoxy-chromen-2-one

6-hydroxy-7-methoxychromen-2-one

6-hydroxy-7-methoxy-2H-chromen-2-one

7-Methoxyesculetin

esculetin 7-methyl ether

6-hudroxy-7-methoxycoumarin

Isoscopoletin (6-Hydroxy-7-methoxycoumarin)

2H-1-Benzopyran-2-one, 6-hydroxy-7-methoxy-

6-HYDROXY-7-METHOXYCOUMARIN USP/EP/BP

6-Hydroxy-7-methoxycoumarin (Isoscopoletine)

Isoscopolamine

776-86-3

Cd0H9O4

Biochemicals and Reagents

BioChemical

Other Fluorescent Labels

Fluorescent Probes, Labels, Particles and Stains

Fluorescent Labels

reagent

standard substance

Coumarins