DMG-PEG 2000

Product Name: DMG-PEG 2000
CAS No.: 160743-62-4
Chemical Name: DMG-PEG 2000
Synonyms: DMG-PEG;mPEG-DMG;DMG-PEG 2000;DMG-mPEG2000;DMG-PEG PEG5000;DMG-PEG PEG 2000;DMG-PEG PEG10000;DMG-PEG PEG40000;DMG-PEG PEG30000;DMG-PEG PEG200000
CBNumber: CB14740239
Formula Weight: 0
MOL File: Mol file

More

Less

DMG-PEG 2000 Property

storage temp.: -20°C, sealed storage, away from moisture and light
solubility: DMSO: 100 mg/mL
form: A crystalline solid
color: White to light yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

BroadPharm

Product number: BP-25496
Product name: DMG-PEG2000
Purity: 99%
Packaging: 1g
Price: $280
Updated: 2021/12/16

BroadPharm

Product number: BP-25496
Product name: DMG-PEG2000
Purity: 99%
Packaging: 2g
Price: $490
Updated: 2021/12/16

DC Chemicals

Product number: DC40169
Product name: DMG-PEG2000
Purity: >98%
Packaging: 1g
Price: $950
Updated: 2021/12/16

DC Chemicals

Product number: DC40169
Product name: DMG-PEG2000
Purity: >98%
Packaging: 2g
Price: $1600
Updated: 2021/12/16

More

Less

DMG-PEG 2000 Chemical Properties,Usage,Production

Description

DMG-PEG 2000, also called 1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000, is used for liposome preparation. DMG-PEG 2000 has become known for lipid nanoparticle (LNP) preparation for siRNA (small interfering RNA) delivery in the COVID-19 vaccine development. DMG-PEG 2000 has been used in studies for anticancer drug delivery studies for hepatocellular, gastrointestinal, neuroendocrine and adrenocortical carcinoma.

Uses

DMG-PEG2000 is used for the preparation of liposomes for siRNA delivery, which can improve the transfection efficiency. It can also be used for the preparation of lipid nanoparticles for in vivo delivery of orally administered plasmid DNA. DMG-PEG2000 can improve the mucus permeability and delivery efficiency of nanoparticles.

Chemical Properties

DMG-PEG 2000 is soluble in ethanol, DMSO and chloroform:methanol (9:1) at a concentration of 5 mg/mL; store at -20°C. Generally transported on dry ice.

Application

DMG-PEG 2000 is a lipid excipient that has been used in combination with other lipids to form lipid nanoparticles (LNPs) for delivery of COVID-19 mRNA vaccines.

in vitro

NP-3 (0.05-1.6 mg/mL; 24 hours) does not decrease the cytotoxicity of cells in 293T, HepG2, A549, and HeLa cell lines, but the DPPC and DMG-PEG coated nanoparticles reduce cell cytotoxicity. In addition, the transfection efficiency of DPPC/DMG-PEG/(lPEI/DNA) nanoparticles (NP-3) in 293 cells is improved, and the maximum transfection efficiency (～76% eGFP positive cells) is observed.

in vivo

NP-3 (oral administration; 150 μg DNA per mouse; single dose) at 12, 24, and 36 h postadministration, luciferin substrate is intraperitoneally injected to verify its permeability. NP-3 group maintains high luciferase expression in the liver, lung, and intestine areas 12-24 h post-treatment.Additionally, NP-3 exhibits 1.5 times higher signal intensity than that of NP-1 or NP-2 group from 12 to 24 h postoral administration.

DMG-PEG 2000 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

DMG-PEG 2000 Suppliers

China 96 India 1 Japan 1 United States 7 Global 105

AVT(Shanghai) Pharmaceutical Tech Co., Ltd.

Tel: 021-58876118 15692161719
Email: avt013@avt-cn.com
Country: China
ProdList: 93
Advantage: 58

Xiamen Sinopeg Biotech Co., Ltd.

Tel: 400-400-9189898
Email: sales@sinopeg.com
Country: China
ProdList: 305
Advantage: 58

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883 15367835770
Fax: 0731-82251112
Email: viola@huatengsci.com
Country: China
ProdList: 5875
Advantage: 58

Chongqing Yusi medical technology cable Co., Ltd.

Tel: 19923757617 18896157519
Email: 18896157519@139.com
Country: China
ProdList: 541
Advantage: 58

Xinyanpomei

Tel: 15850660754
Email: 15850660754@163.com
Country: China
ProdList: 173
Advantage: 58

NBC (Shanghai) Chemical Co.,Ltd

Tel: 13671558889
Fax: 021-56789108
Email: market@nbcchem.com
Country: China
ProdList: 184
Advantage: 58

Shochem (Shanghai) Co.,Ltd

Tel: 13611745246 13816874662
Email: sales@shochem.com
Country: China
ProdList: 541
Advantage: 58

Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 8418
Advantage: 55

Suzhou Highfine Biotech Co., Ltd

Tel: 0512-68311833 13962195826
Fax: 0512-68417696
Email: wuhao@highfine.com
Country: China
ProdList: 499
Advantage: 75

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

More

Less

View Lastest Price from DMG-PEG 2000 manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: Methoxypoly(ethylene glycol) dimyristoyl glycerol 160743-62-4
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 98%
Supply Ability: 1
Release date: 2021-06-22

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: DMG-PEG2000（mPEG-DMG） 160743-62-4
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle , 10g/bottle, 100g/bottle
Release date: 2024-07-26

160743-62-4, DMG-PEG 2000Related Search:

1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT PEG2000-C-DMG 1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[3-(2-pyridyldithio)propionate] (sodiuM salt) 1-STERAOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (MONOSODIUM SALT) Hexadecanoic acid, 1,1'-[(1S)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester 1-STEAROYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE DODAP 1-OCTADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE DODMA Polyethylene Glycol

DMG-PEG 2000

1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000

1,?2-?Dimyristoyl-?sn-?glycero-?3-?methoxypolyethylene glycol

Polyethylene glycol [PEG] 2000 dimyristoyl glycerol [DMG]

Methoxypoly(ethylene glycol) dimyristoyl glycerol

DMG-mPEG2000

Poly(oxy-1,2-ethanediyl), α-[2,3-bis[(1-oxotetradecyl)oxy]propyl]-ω-methoxy-

1,2-Dimyristoyl-sn-glycero-3-methoxypolyethylene glycol 2000

mPEG-DMG

Inhibitor,therapy,T2D,lPEI/DNA nanoparticle,type II diabete,A549,HepG2,inhibit,HeLa,DMG-PEG 2000,DMGPEG 2000,293T,nucleic acid,DMG PEG 2000

DMG-PEG PEG 2000

DMG-PEG

1,2-dimyristoyl-rac-glycerol-3-methoxypolyethylene glycol-2000

MPEG-2000 glyceryl 1,2-dimyristate

DMG-PEG PEG10000

DMG-PEG PEG5000

DMG-PEG PEG40000

DMG-PEG PEG30000

DMG-PEG PEG200000

DMG-PEG2000(mPEG-DMG)

1-(2-methoxyethoxy)-3-(tetradecanoyloxy)propan-2-yl tetradecanoate

1,2-Biscarnitine-rac-glycerin-3-methoxypolyethylene glycol 2000

160743-62-4

DMG