Sodium thiomethoxide

ChemicalBook > CAS DataBase List > Sodium thiomethoxide

Sodium thiomethoxide

Product Name: Sodium thiomethoxide
CAS No.: 5188-07-8
Chemical Name: Sodium thiomethoxide
Synonyms: SODIUM METHANETHIOLATE;SODIUM METHYL MERCAPTIDE;METHYL MERCAPTAN SODIUM SALT;Sodium thiomethylate;Sodium methylthiolate;SODIUM METHYLMERCAPTAN;SODIUM THIOMETHOXIDE, 21 VOL. % SOLN IN WATER, A PRODUCT OF ELF ATOCHEM (SMM);Sodium me;thioformate;methanethiolate
CBNumber: CB1476576
Molecular Formula: CH3NaS
Formula Weight: 70.09
MOL File: 5188-07-8.mol

Less

Sodium thiomethoxide Property

Density: 1.12[at 20℃]
vapor pressure: 29hPa at 25℃
Flash point:: 27°C
storage temp.: Air and moisture sensitive. Store under inert gas. Sensitive to carbon dioxide Exposure to moisture.
solubility: soluble in Water
form: Powder
color: White to off-white
Water Solubility: soluble
Merck: 14,5956
BRN: 3592983
InChI: InChI=1S/CH4S.Na/c1-2;/h2H,1H3;/q;+1/p-1
InChIKey: RMBAVIFYHOYIFM-UHFFFAOYSA-M
SMILES: CS[Na]
LogP: -2.33 at 20℃
CAS DataBase Reference: 5188-07-8(CAS DataBase Reference)
EPA Substance Registry System: Methanethiol, sodium salt (5188-07-8)

Less

Safety

Hazard Codes: C,F
Risk Statements: 31-34-20/21/22-11-35-25-10
Safety Statements: 26-36/37/39-45-16
RIDADR: UN 3263 8/PG 3
WGK Germany: 3
F: 1-34-10-13
HazardClass: 4.3
PackingGroup: II
HS Code: 29309090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 281018
Product name: Sodium thiomethoxide
Purity: 95%
Packaging: 1g
Price: $46.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 281018
Product name: Sodium thiomethoxide
Purity: 95%
Packaging: 5g
Price: $125
Updated: 2024/03/01

TCI Chemical

Product number: M0096
Product name: Methyl Mercaptan Sodium Salt (ca. 15% in Water)
Packaging: 25g
Price: $38
Updated: 2024/03/01

TCI Chemical

Product number: M0096
Product name: Methyl Mercaptan Sodium Salt (ca. 15% in Water)
Packaging: 500g
Price: $144
Updated: 2024/03/01

Sigma-Aldrich

Product number: 71742
Product name: Sodium methanethiolate
Purity: technical, ≥90% (RT)
Packaging: 5g
Price: $122
Updated: 2024/03/01

Less

Sodium thiomethoxide Chemical Properties,Usage,Production

Description

Sodium methanethiolate or sodium thiomethoxide (CH3SNa, MeSNa) is the sodium conjugate base of methanethiol. This compound is commercially available as a white solid. Sodium Methanethiolate is used as a nucleophile in organic synthesis. This compound is also being used as a reagent to synthesize thiol-based suberoylanilide hydroxamic acid (SAHA) analogues, compounds that act as potent histone deacetylase inhibitors. It reacts with trifluoroacetic acid and water to produce the active form of sodium trifluoroacetate. The reaction mechanism is likely due to the formation of a bicyclic heterocycle that has been shown to be effective against a number of bacteria.

Chemical Properties

Very faint yellowish red clear liquid

Uses

Used to prepare a C-21 thioether of methyl 16-prednisolonecarboxylate by mesylate displacement.

Uses

Sodium thiomethoxide is a strong nucleophile used for the synthesis of methyl aryl sulfides from halo-arenes. Alkanethiolates are efficient reagents for SN2 dealkylation of esters and aryl ethers.

Reactivity Profile

Sodium thiomethoxide is a powerful nucleophile that can be used to prepare methylthioether and other organic compounds like ethyl bromide. Its hydrolysis in moist air produces methanethiol, which has a low odor threshold and a noxious fecal smell.

Purification Methods

Dissolve the salt (10g) in EtOH (10mL) and add Et2O (100mL). Cool and collect the precipitate, wash it with Et2O and dry it in a vacuum. It is a white powder which is very soluble in EtOH and H2O. [Billmann & Jensen Bull Soc Chim Fr 3 2318 1936, Beilstein 1 III 1212.]

Sodium thiomethoxide Preparation Products And Raw materials

Raw materials

Carbon disulfide Methanol Sodium hydroxide

Preparation Products

2-Aminoethylmethylsulfone hydrochloride Simetryne Prometryn 2-(METHYLTHIO)ETHANOL 2-(Methylthio)pyrazine 4,6-DICHLORO-2-(TRIFLUOROMETHYL)QUINOLINE 2-(METHYLTHIO)THIOPHENE Ametryn Methylthio acetaldoxime 5-(METHYLSULFONYL)THIOPHENE-2-CARBOXYLIC ACID ETHYL METHANESULFONYLACETATE 4-Methylthio-2-butanone Dimethyl sulfide METHYL MERCAPTAN Prairie Net Wettable Powder ALDICARB-OXIME 2-Methyl-3-(methylthio)pyrazine 5-(METHYLTHIO)THIOPHENE-2-CARBOXYLIC ACID ALDICARB 6-(METHYLTHIO)PYRIDINE-3-CARBOXYLIC ACID Methylthioethane

Less

Sodium thiomethoxide Suppliers

Americas 1 Australia 1 Belgium 1 Canada 1 China 293 Europe 1 Germany 2 India 12 Japan 1 Slovakia 1 Switzerland 1 United Kingdom 4 United States 18 Global 337

Shanghai YouPeng Chemical Co. Ltd.

Tel: 021-69005955 13701776567
Fax: 021-69005775
Email: youpengchem@163.com
Country: China
ProdList: 4293
Advantage: 56

Shandong Xiangfei Chemical Co. LTD

Tel: 13105464419
Email: 13105464419@163.com
Country: China
ProdList: 126
Advantage: 58

Nanjing Xiezun Chemical Co., Ltd.

Tel: 025-85629050 13912997845
Fax: 025-85620080
Email: 179109486@qq.com
Country: China
ProdList: 25
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9499
Advantage: 66

Shanghai QiQiao Biological Technology Co., Ltd.

Tel: 021-37653318; 15221675714
Email: 515366396@qq.com
Country: China
ProdList: 2089
Advantage: 58

Jinan Kabotang Biological Technology Co.,Ltd.

Tel: 0531-61320525 15866703830
Email: 495745175@qq.com
Country: China
ProdList: 8141
Advantage: 58

Shandong Qianyuan Polymer Material Co. , Ltd.

Tel: 18678041314 18765609661
Email: 2547772582@qq.com
Country: China
ProdList: 878
Advantage: 58

Chongqing Xingcan Pharmaceutical Technology Co., Ltd.

Tel: 15523000485
Email: xingcanyaoye@sina.com
Country: China
ProdList: 1686
Advantage: 58

Hubei DAHAO Chemical Co., Ltd.

Tel: 027-59106191 13986034860
Email: 1400828855@qq.com
Country: China
ProdList: 8933
Advantage: 58

Henan Yanyuan Biotechnology Co., Ltd

Tel: 18637186683
Email: 2392060329@qq.com
Country: China
ProdList: 31
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing dtftchem Technology Co., Ltd.

Tel: 010-60275820 13031183356
Fax: 010-60270825
Email: elainezt@sina.com
Country: China
ProdList: 1390
Advantage: 62

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44688
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12390
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Secco work (Beijing) chemical technology co., LTD

Tel: 0566-8928158
Fax: 010-69755668
Email: 343367102@QQ.COM
Country: China
ProdList: 360
Advantage: 54

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18738
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11707
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Nanjing Vital Chemical Co., Ltd.

Tel: Please Send Email 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 4378
Advantage: 65

Wuhan Fortuna Chemical Co., Ltd

Tel: 027-59207852 13308628970
Fax: QQ3130921841
Email: buy@fortunachem.com
Country: China
ProdList: 2871
Advantage: 58

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Yurui (Shanghai) Chemical Co., Ltd.

Tel: 21-50456736 13818239876
Fax: 021-50761379
Email: sales21@riyngroup.com
Country: China
ProdList: 1052
Advantage: 30

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 18017383231 18017383231
Fax: qq：2817624287
Email: lyh_antaeus@163.com
Country: China
ProdList: 9347
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Ningxia Hengrui Biotechnology Co., Ltd.

Tel: +86-951-6015036,+1-520-957-2778
Fax: +86-951-6015036
Email: nxhengrui@163.com
Country: China
ProdList: 8
Advantage: 58

Cantotech Chemicals, Ltd.

Tel: 86-0755-86635001
Fax: 86-0755-22642228
Email: cantotech@126.com
Country: China
ProdList: 4566
Advantage: 55

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

Zouping Mingxing Chemical Co.,Ltd.

Tel: 86-13605431940 13605431940
Fax: 0086-0543-2240079
Email: zpmxchemical@126.com
Country: China
ProdList: 1999
Advantage: 62

Shanghai GAOXIANG Chemical Co., Ltd.

Tel: 021-57816257 18930243658
Fax: 021-57816257
Email: fecpo@139.com
Country: China
ProdList: 295
Advantage: 55

Beijing Universal Century Technology Co., Ltd.

Tel: 400-8706899
Fax: 400-8706899
Email: hysj_bj.com
Country: China
ProdList: 3583
Advantage: 55

Shanghai Meishui Chemical Technology Co., Ltd

Tel: 021-60549325 18616193163
Fax: 021-33250306
Country: China
ProdList: 4526
Advantage: 56

RiZhao LiDeShi Chemical Co., Ltd.

Tel: 010-51268198
Fax: 010-63833209
Email: leadershipchem@126.com
Country: China
ProdList: 2546
Advantage: 58

Mei Lan Industrial (Shanghai) Co., Ltd.

Tel: 021-58958189
Fax: 021-58957967
Email: wouchina@126.com
Country: China
ProdList: 2666
Advantage: 55

Shanghai GaoLang Chemical Technology Co., Ltd.

Tel: 021-57340939 18017297327
Fax: 021-37210791
Email: sales@gaolangchemical.com
Country: China
ProdList: 892
Advantage: 55

Shanghai ideal Industrial Co., Ltd.

Tel: 021-58957966 18930537195
Fax: 021-60899437
Email: wouchina@126.com
Country: China
ProdList: 3027
Advantage: 58

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

GuangTuo Chemical (Shanghai) Co., Ltd.

Tel: 021-60899189-8001 18918189673
Fax: 021-60899304
Email: gtchem@126.com
Country: China
ProdList: 2656
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Credit-Chem Co., Ltd.

Tel: 400-821-5857 021-64326257
Fax: 021-64393586 QQ;2798200800
Email: credit-chem@foxmail.com
Country: China
ProdList: 5219
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10276
Advantage: 55

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 16166
Advantage: 55

Less

View Lastest Price from Sodium thiomethoxide manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Sodium thiomethoxide 5188-07-8
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99.5%
Supply Ability: 100
Release date: 2024-11-06

Hebei Mojin Biotechnology Co., Ltd

Product: Sodium thiomethoxide 5188-07-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-09-22

Henan Aochuang Chemical Co.,Ltd.

Product: Sodium thiomethoxide 5188-07-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-17

5188-07-8, Sodium thiomethoxideRelated Search:

Sodium thiomethoxide solution

METHANETHIOL SODIUM SALT

METHYL MERCAPTAN SODIUM SALT

SODIUM METHANETHIOLATE

SODIUM METHYL MERCAPTIDE

SODIUM METHYL SULFIDE

SODIUM THIOMETHOXIDE

Sodium thiomethoxyde

SODIUM THIOMETHOXIDE, 21 VOL. % SOLN IN WATER, A PRODUCT OF ELF ATOCHEM (SMM)

1-Methanethiolsodiumsalt

Sodium methanethiol

Sodium methylthiolate

Sodium thiomethylate

Sodium thiomethoxide, pure, 95%

Sodium thiomethoxide, Methanethiol sodium salt

SODIUM METHYLMERCAPTAN

METHYL MERCAPTAN SODIUM SALT: 15% IN WATER

Methyl Mercaptan Sodium Salt (ca. 15% in Water)

Methanethiol sodium salt, Sodium methanethiolate, Sodium thiomethoxide

Sodium thiomethoxide, 95%, pure

Sodiothiomethane

Sodium Methanethiolate Solution

Sodium methanethiolate, 21% aq. soln.

Sodium methanethiolate ,95%

thioformate

Methanethiol, sodiuMsalt (1:1)

SodiuM Methanethiolate technical, >=90% (RT)

SodiuM thioMethoxide 95%

SodiuM thioMethoxide solution 21% in H2O

SodiuM thioMethoxide, 20% in water

Sodium Methanethiolate (~20% in Water)

sodiuM Methylsulfanide

SodiuM Methanethiolate, 15 wt.% solution in H2O

Sodium methanethiolate, 21% aqueous solution

Sodium me

Sodium methionine

Sodium thiomethoxide, 15% in water

methanethiolate

High purity Sodium thiomethoxide

5188-07-8

5188-7-8

1201108

1201-10-8

CH3NaS

CH3SNa

Building Blocks

Na (Sodium) Compounds (excluding simple sodium salts)

Typical Metal Compounds

Classes of Metal Compounds

Sulfur Compounds

Thiol/Mercaptan Salts

Organic Building Blocks

Classes of Metal Compounds

Na (Sodium) Compounds (excluding simple sodium salts)

Typical Metal Compounds

API

Aliphatics

Sulfur & Selenium Compounds