Description
ChemicalBook > CAS DataBase List > 2-Aminoethylmethylsulfone hydrochloride

2-Aminoethylmethylsulfone hydrochloride

Description
Product Name
2-Aminoethylmethylsulfone hydrochloride
CAS No.
104458-24-4
Chemical Name
2-Aminoethylmethylsulfone hydrochloride
Synonyms
CL126;Lapatinib hyrochloride;Lapatinib Intermediate 1;2-AMINOETHYLMETHYLSULFONE HCL;2-Methane sulfonyl ethyl aMine;2-(Methylsulfonyl)ethanaMine HCl;2-(Methylsulfonyl)Ethylamine HCl;2-MESYLETHAN-1-AMINE HYDROCHLORIDE;AMinoethylMethylsulfonehydrochloride;AMinoethylMethylsulphone hydrochloride
CBNumber
CB01113134
Molecular Formula
C3H10ClNO2S
Formula Weight
159.63
MOL File
104458-24-4.mol
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2-Aminoethylmethylsulfone hydrochloride Property

Melting point:
168.0 to 172.0 °C
storage temp. 
Room temperature.
InChIKey
AMYYUKGKCJKCBI-UHFFFAOYSA-N
CAS DataBase Reference
104458-24-4(CAS DataBase Reference)
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Safety

HS Code 
29211990
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2464
Product name
2-Aminoethyl Methyl Sulfone Hydrochloride
Purity
>98.0%(N)(T)
Packaging
5g
Price
$45
Updated
2018/11/22
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2-Aminoethylmethylsulfone hydrochloride Chemical Properties,Usage,Production

Description

Lapatinib is a new drug targeted for the treatment of breast cancer developed by GlaxoSmithKline, which was approved for marketing by the US Food and Drug Administration on March 13, 2007. The currently approved indications are advanced mastocarcinoma treated with lapatinib and capecitabine or metastatic breast cancer, and breast cancer patients must be treated first in other first-class drugs. Its trade name is Tykerb in the United States. On December 14, 2007, the European Medicines Agency (EMEA) approved for marketing of lapatinib in Europe, and the trade name is Tyverb. Breast cancer molecular targeted therapy is the treatment for oncogene related with occurrence and development of breast cancer, and for its related expression product. Molecular targeted drugs control the changes of gene expression in the cell through blocking signal transduction of tumor cell or related cell, thereby inhibiting or killing tumor cells.
Lapatinib is a small molecule epidermal growth factor tyrosine kinase inhibitor orally. Clinical trials have shown that lapatinib has a very good clinical effect in patients with HER2 breast cancer who have been resistant to Roche's Herceptin. In vitro, the inhibitory effect of lapatinib on the growth of Her-2 overexpressing breast cancer cell lines was significant. Lapatinib is also highly effective in the Phase I clinical trial of Her-2 overexpression in advanced breast cancer and has no cross-resistance with Herceptin (trastuzumab). Unlike Herceptin (trastuzumab), its structure is small molecules, so it could get through the blood-brain barrier, thereby having a certain therapeutic effect for breast cancer brain metastases.

Chemical Properties

Off-white to yellow solid

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2-Aminoethylmethylsulfone hydrochloride Suppliers

Yancheng Kangqiang Medical Raw Material Co., Ltd
Tel
+86-519-83879978
Fax
+86-519-83879968
Email
sales@chemsanyou.com
Country
China
ProdList
269
Advantage
62
Shandong Platinum Pharmaceutical Co., Ltd.
Tel
15666777973
Email
sales@boyuanpharm.com
Country
CHINA
ProdList
91
Advantage
58
TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.
Tel
022-60979687,QQ2199772478
Fax
86-22-60979672
Email
marketing@pharmacn.com
Country
China
ProdList
143
Advantage
61
J & K SCIENTIFIC LTD.
Tel
400-666-7788 +86-10-82848833
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
+86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
Fax
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing)
Email
sh@meryer.com
Country
China
ProdList
40269
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3579
Advantage
66
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 qq:2355568890
Fax
0086-21-50182339
Email
sales@demochem.com; export1@demochem.com
Country
China
ProdList
2585
Advantage
57
BeiJing Hwrk Chemicals Limted
Tel
4006990298;010-57411839;0757-86311057;021-51691807
Fax
010-87653215;0757-86311057;021-55236763
Email
sales@hwrkchemical.com
Country
China
ProdList
14684
Advantage
55
Energy Chemical
Tel
021-58432009 / 400-005-6266
Fax
021-58436166-800
Email
info@energy-chemical.com
Country
China
ProdList
44025
Advantage
61
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View Lastest Price from 2-Aminoethylmethylsulfone hydrochloride manufacturers

career henan chemical co
Product
2-Aminoethylmethylsulfone hydrochloride 104458-24-4
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 480
Release date
2019-09-01
career henan chemical co
Product
2-Aminoethylmethylsulfone hydrochloride 104458-24-4
Price
US $150.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1000kg
Release date
2018-07-27
career henan chemical co
Product
2-Aminoethylmethylsulfone hydrochloride 104458-24-4
Price
US $150.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
20KG
Release date
2018-07-27

104458-24-4, 2-Aminoethylmethylsulfone hydrochlorideRelated Search:


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