Description
ChemicalBook > CAS DataBase List > 2-Aminoethylmethylsulfone hydrochloride

2-Aminoethylmethylsulfone hydrochloride

Description
Product Name
2-Aminoethylmethylsulfone hydrochloride
CAS No.
104458-24-4
Chemical Name
2-Aminoethylmethylsulfone hydrochloride
Synonyms
2-Methanesulfonylethan-1-aMine hydrochloride;2-(methylsulfonyl)ethan-1-amine hydrochloride;2-(Methylsulfonyl)Ethylamine HCl;CL126;)ethanamine hydrochL;Lapatinib hyrochloride;Lapatinib Intermediate 1;2-AMINOETHYLMETHYLSULFONE HCL;2-Methane sulfonyl ethyl aMine;2-(Methylsulfonyl)ethanaMine HCl
CBNumber
CB01113134
Molecular Formula
C3H10ClNO2S
Formula Weight
159.63
MOL File
104458-24-4.mol
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2-Aminoethylmethylsulfone hydrochloride Property

Melting point:
168.0 to 172.0 °C
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
InChIKey
AMYYUKGKCJKCBI-UHFFFAOYSA-N
CAS DataBase Reference
104458-24-4(CAS DataBase Reference)
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Safety

HS Code 
29211990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2464
Product name
2-Aminoethyl Methyl Sulfone Hydrochloride
Purity
>98.0%(N)(T)
Packaging
5g
Price
$44
Updated
2021/12/16
TRC
Product number
M339108
Product name
2-(Methylsulfonyl)ethylamineHydrochloride
Packaging
2.5g
Price
$95
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA53226
Product name
2-Aminoethylmethylsulfone Hydrochloride
Packaging
10 g
Price
$120
Updated
2021/12/16
Apolloscientific
Product number
OR12674
Product name
2-Aminoethylmethylsulphone hydrochloride
Packaging
10g
Price
$129
Updated
2021/12/16
SynQuest Laboratories
Product number
8163-5-X0
Product name
2-Aminoethylmethylsulfone hydrochloride
Packaging
10 g
Price
$152
Updated
2021/12/16
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2-Aminoethylmethylsulfone hydrochloride Chemical Properties,Usage,Production

Description

Lapatinib is a new drug targeted for the treatment of breast cancer developed by GlaxoSmithKline, which was approved for marketing by the US Food and Drug Administration on March 13, 2007. The currently approved indications are advanced mastocarcinoma treated with lapatinib and capecitabine or metastatic breast cancer, and breast cancer patients must be treated first in other first-class drugs. Its trade name is Tykerb in the United States. On December 14, 2007, the European Medicines Agency (EMEA) approved for marketing of lapatinib in Europe, and the trade name is Tyverb. Breast cancer molecular targeted therapy is the treatment for oncogene related with occurrence and development of breast cancer, and for its related expression product. Molecular targeted drugs control the changes of gene expression in the cell through blocking signal transduction of tumor cell or related cell, thereby inhibiting or killing tumor cells.
Lapatinib is a small molecule epidermal growth factor tyrosine kinase inhibitor orally. Clinical trials have shown that lapatinib has a very good clinical effect in patients with HER2 breast cancer who have been resistant to Roche's Herceptin. In vitro, the inhibitory effect of lapatinib on the growth of Her-2 overexpressing breast cancer cell lines was significant. Lapatinib is also highly effective in the Phase I clinical trial of Her-2 overexpression in advanced breast cancer and has no cross-resistance with Herceptin (trastuzumab). Unlike Herceptin (trastuzumab), its structure is small molecules, so it could get through the blood-brain barrier, thereby having a certain therapeutic effect for breast cancer brain metastases.

Chemical Properties

Off-white to yellow solid

Uses

2-(Methylsulfonyl)ethylamine Hydrochloride is used in the synthetic preparation of potent and selective PI3Kδ inhibitors.

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2-Aminoethylmethylsulfone hydrochloride Suppliers

Shandong Platinum Pharmaceutical Co., Ltd.
Tel
0531-69954981 88963280 15666777973
Fax
0531-88964879
Email
sales@boyuanpharm.com
Country
China
ProdList
165
Advantage
58
Changzhou Idea-Works Medical Technology Co., Ltd
Tel
0519-83879978
Email
sales@ideaworkspharm.com
Country
China
ProdList
85
Advantage
62
Nanjing FuRuisi Medical Technology Co., Ltd.
Tel
025-83221260
Fax
02583221260
Email
renqing401@163.com
Country
China
ProdList
129
Advantage
55
TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.
Tel
022-60979687 18002122726
Fax
86-22-60979672
Email
marketing@pharmacn.com
Country
China
ProdList
132
Advantage
61
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169107
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40310
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3579
Advantage
66
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 qq:2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2582
Advantage
57
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18516978288
Fax
010-89508210
Email
sales.gd@hwrkchemical.com
Country
China
ProdList
17295
Advantage
55
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View Lastest Price from 2-Aminoethylmethylsulfone hydrochloride manufacturers

Hebei Guanlang Biotechnology Co., Ltd.
Product
2-Aminoethylmethylsulfone hydrochloride 104458-24-4
Price
US $9.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2021-10-13
Wuhan wingroup Pharmaceutical Co., Ltd
Product
2-Aminoethylmethylsulfone hydrochloride 104458-24-4
Price
US $30.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 Tons
Release date
2022-03-23
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Aminoethylmethylsulfone hydrochloride 104458-24-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-10

104458-24-4, 2-Aminoethylmethylsulfone hydrochlorideRelated Search:


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