2-Aminoethylmethylsulfone hydrochloride

Description

Product Name: 2-Aminoethylmethylsulfone hydrochloride
CAS No.: 104458-24-4
Chemical Name: 2-Aminoethylmethylsulfone hydrochloride
Synonyms: 2-Methanesulfonylethan-1-aMine hydrochloride;2-(methylsulfonyl)ethan-1-amine hydrochloride;2-(Methylsulfonyl)Ethylamine HCl;CL126;)ethanamine hydrochL;Lapatinib hyrochloride;Lapatinib Intermediate 1;2-AMINOETHYLMETHYLSULFONE HCL;2-Methane sulfonyl ethyl aMine;2-(Methylsulfonyl)ethanaMine HCl
CBNumber: CB01113134
Molecular Formula: C3H10ClNO2S
Formula Weight: 159.63
MOL File: 104458-24-4.mol

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2-Aminoethylmethylsulfone hydrochloride Property

Melting point:: 168.0 to 172.0 °C
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form: Solid
color: White to Off-White
Stability:: Hygroscopic
InChIKey: AMYYUKGKCJKCBI-UHFFFAOYSA-N
CAS DataBase Reference: 104458-24-4(CAS DataBase Reference)

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Safety

HS Code: 29211990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2464
Product name: 2-Aminoethyl Methyl Sulfone Hydrochloride
Purity: >98.0%(N)(T)
Packaging: 5g
Price: $44
Updated: 2024/03/01

TRC

Product number: M339108
Product name: 2-(Methylsulfonyl)ethylamineHydrochloride
Packaging: 2.5g
Price: $95
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA53226
Product name: 2-Aminoethylmethylsulfone Hydrochloride
Packaging: 10g
Price: $120
Updated: 2021/12/16

Apolloscientific

Product number: OR12674
Product name: 2-Aminoethylmethylsulphone hydrochloride
Packaging: 10g
Price: $129
Updated: 2021/12/16

SynQuest Laboratories

Product number: 8163-5-X0
Product name: 2-Aminoethylmethylsulfone hydrochloride
Packaging: 10g
Price: $152
Updated: 2021/12/16

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2-Aminoethylmethylsulfone hydrochloride Chemical Properties,Usage,Production

Description

Lapatinib is a new drug targeted for the treatment of breast cancer developed by GlaxoSmithKline, which was approved for marketing by the US Food and Drug Administration on March 13, 2007. The currently approved indications are advanced mastocarcinoma treated with lapatinib and capecitabine or metastatic breast cancer, and breast cancer patients must be treated first in other first-class drugs. Its trade name is Tykerb in the United States. On December 14, 2007, the European Medicines Agency (EMEA) approved for marketing of lapatinib in Europe, and the trade name is Tyverb. Breast cancer molecular targeted therapy is the treatment for oncogene related with occurrence and development of breast cancer, and for its related expression product. Molecular targeted drugs control the changes of gene expression in the cell through blocking signal transduction of tumor cell or related cell, thereby inhibiting or killing tumor cells.
Lapatinib is a small molecule epidermal growth factor tyrosine kinase inhibitor orally. Clinical trials have shown that lapatinib has a very good clinical effect in patients with HER2 breast cancer who have been resistant to Roche's Herceptin. In vitro, the inhibitory effect of lapatinib on the growth of Her-2 overexpressing breast cancer cell lines was significant. Lapatinib is also highly effective in the Phase I clinical trial of Her-2 overexpression in advanced breast cancer and has no cross-resistance with Herceptin (trastuzumab). Unlike Herceptin (trastuzumab), its structure is small molecules, so it could get through the blood-brain barrier, thereby having a certain therapeutic effect for breast cancer brain metastases.

Chemical Properties

Off-white to yellow solid

Uses

2-(Methylsulfonyl)ethylamine Hydrochloride is used in the synthetic preparation of potent and selective PI3Kδ inhibitors.

2-Aminoethylmethylsulfone hydrochloride Preparation Products And Raw materials

Raw materials

FUMING SULFURIC ACID Sodium thiomethoxide Hexane Ethanol Sodium chloride 3-Chloroperoxybenzoic acid Di-tert-butyl dicarbonate Tetrahydrofuran Diethyl ether 2-Bromoethylamine hydrobromide Ethyl acetate Sodium bicarbonate Magnesium sulfate PETROLEUM ETHER

Preparation Products

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2-Aminoethylmethylsulfone hydrochloride Suppliers

Americas 1 Canada 1 China 309 Europe 1 Germany 4 India 22 Japan 1 United Kingdom 6 United States 29 Global 374

TCI Chemicals (India) Pvt. Ltd.

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View Lastest Price from 2-Aminoethylmethylsulfone hydrochloride manufacturers

Hebei Chuanghai Biotechnology Co,.LTD

Product: 2-Aminoethylmethylsulfone hydrochloride 104458-24-4
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-20

Hebei Fengjia New Material Co., Ltd

Product: 2-Aminoethylmethylsulfone hydrochloride 104458-24-4
Price: US $7.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 100000
Release date: 2024-08-08

Hebei Weibang Biotechnology Co., Ltd

Product: 2-Aminoethylmethylsulfone hydrochloride 104458-24-4
Price: US $9.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2021-10-13

104458-24-4, 2-Aminoethylmethylsulfone hydrochlorideRelated Search:

Topotecan hydrochloride Diethylamine hydrochloride 2-Phenylethylamine hydrochloride Ethylamine hydrochloride Triethylamine hydrochloride 4-Methylaniline hydrochloride 1-Methyl-4-(methylsulfonyl)-benzene 2-Nitro-4-methylsulfonyltoluene 2-[(4-CHLOROPHENYL)SULFONYL]ETHANETHIOAMIDE 2-[(4-CHLOROPHENYL)SULFONYL]-N'-HYDROXYETHANIMIDAMIDE Lapatinib 4,5-DICHLORO-1-[2-(PHENYLSULFONYL)ETHYL]-1H-IMIDAZOLE 3-HYDRAZINOTETRAHYDRO-1H-1L6-THIOPHENE-1,1-DIONE HYDROCHLORIDE 2-Aminoethylmethylsulfone hydrochloride 4,5-DICHLORO-1-(2-[(4-CHLOROPHENYL)SULFONYL]ETHYL)-2-METHYL-1H-IMIDAZOLE 3-(4-CHLOROPHENYL)-5-[(DIMETHYLAMINO)METHYLENE]-1LAMBDA6,3-THIAZOLANE-1,1,4-TRIONE 3-(3,4-DICHLOROPHENYL)-1LAMBDA6,3-THIAZOLANE-1,1,4-TRIONE 3-(2,5-DICHLOROPHENYL)-1LAMBDA6,3-THIAZOLANE-1,1,4-TRIONE

2-MESYLETHAN-1-AMINE HYDROCHLORIDE

2-(Methylsulfonyl)-ethanamine hydrochloride

2-(Methylsulfonyl)Ethylamine HCl

2-(methylsulfonyl)ethylamine hydrochloride

2-Aminoethylmethylsulfone hydrochloride

2-(METHANE SULFONYL)ETHYLAMINE HYDROCHLORIDE

2-(Methylsulfonyl)ethanamine hydrochloride ,95%

Lapatinib Intermediate 1

2-(Methylsulfonyl)ethanaMine hydrogen chloride

2-Methanesulfonylethan-1-aMine hydrochloride

2-(Methylsulfonyl)ethanaMine HCl

AMinoethylMethylsulphone hydrochloride

2-AMINOETHYLMETHYLSULFONE HCL

2-Methane sulfonyl ethyl aMine

AMinoethylMethylsulfonehydrochloride

2 - (thiaMphenicol) ethylaMine hydrochloride

Lapatinib hyrochloride

CL126

2-Aminoethyl Methyl Sulfone Hydrochloride &gt

)ethanamine hydrochL

2-Aminoethylmethyl sulfone hydrobromide

2-(Methylsulfonyl) Ethylamine HCL(For export only)

2-Aminoethylmethylsulfone hydrochloride ISO 9001：2015 REACH

2-(methylsulfonyl)ethan-1-amine hydrochloride

2-Aminoethylmethylsulfone Hydrochloride CAS NO.104458-24-4

2-(Methane sulphonyl) ethylamine HCL

Ethanamine, 2-(methylsulfonyl)-, hydrochloride (1:1)

Ethanamine, 2-(methylsulfonyl)-, hydrochloride

2-Aminoethyl Methyl Sulfone Hydrochloride, 98%+

2-(Methylsulfonyl)ethanamine hydrochlo

104458-24-4

140058-24-4

102458-24-4

C3H9NO2SHCl

Lapatinib

Intermediate of lapatinib ditosylate

1

104458-24-4