2-Aminoethylmethylsulfone hydrochloride
Description- Product Name
- 2-Aminoethylmethylsulfone hydrochloride
- CAS No.
- 104458-24-4
- Chemical Name
- 2-Aminoethylmethylsulfone hydrochloride
- Synonyms
- 2-Methanesulfonylethan-1-aMine hydrochloride;2-(methylsulfonyl)ethan-1-amine hydrochloride;2-(Methylsulfonyl)Ethylamine HCl;CL126;)ethanamine hydrochL;Lapatinib hyrochloride;Lapatinib Intermediate 1;2-AMINOETHYLMETHYLSULFONE HCL;2-Methane sulfonyl ethyl aMine;2-(Methylsulfonyl)ethanaMine HCl
- CBNumber
- CB01113134
- Molecular Formula
- C3H10ClNO2S
- Formula Weight
- 159.63
- MOL File
- 104458-24-4.mol
2-Aminoethylmethylsulfone hydrochloride Property
- Melting point:
- 168.0 to 172.0 °C
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
- InChIKey
- AMYYUKGKCJKCBI-UHFFFAOYSA-N
- CAS DataBase Reference
- 104458-24-4(CAS DataBase Reference)
Safety
- HS Code
- 29211990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- A2464
- Product name
- 2-Aminoethyl Methyl Sulfone Hydrochloride
- Purity
- >98.0%(N)(T)
- Packaging
- 5g
- Price
- $44
- Updated
- 2024/03/01
- Product number
- M339108
- Product name
- 2-(Methylsulfonyl)ethylamineHydrochloride
- Packaging
- 2.5g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- FA53226
- Product name
- 2-Aminoethylmethylsulfone Hydrochloride
- Packaging
- 10g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- OR12674
- Product name
- 2-Aminoethylmethylsulphone hydrochloride
- Packaging
- 10g
- Price
- $129
- Updated
- 2021/12/16
- Product number
- 8163-5-X0
- Product name
- 2-Aminoethylmethylsulfone hydrochloride
- Packaging
- 10g
- Price
- $152
- Updated
- 2021/12/16
2-Aminoethylmethylsulfone hydrochloride Chemical Properties,Usage,Production
Description
Lapatinib is a new drug targeted for the treatment of breast cancer developed by GlaxoSmithKline, which was approved for marketing by the US Food and Drug Administration on March 13, 2007. The currently approved indications are advanced mastocarcinoma treated with lapatinib and capecitabine or metastatic breast cancer, and breast cancer patients must be treated first in other first-class drugs. Its trade name is Tykerb in the United States. On December 14, 2007, the European Medicines Agency (EMEA) approved for marketing of lapatinib in Europe, and the trade name is Tyverb. Breast cancer molecular targeted therapy is the treatment for oncogene related with occurrence and development of breast cancer, and for its related expression product. Molecular targeted drugs control the changes of gene expression in the cell through blocking signal transduction of tumor cell or related cell, thereby inhibiting or killing tumor cells.
Lapatinib is a small molecule epidermal growth factor tyrosine kinase inhibitor orally. Clinical trials have shown that lapatinib has a very good clinical effect in patients with HER2 breast cancer who have been resistant to Roche's Herceptin. In vitro, the inhibitory effect of lapatinib on the growth of Her-2 overexpressing breast cancer cell lines was significant. Lapatinib is also highly effective in the Phase I clinical trial of Her-2 overexpression in advanced breast cancer and has no cross-resistance with Herceptin (trastuzumab). Unlike Herceptin (trastuzumab), its structure is small molecules, so it could get through the blood-brain barrier, thereby having a certain therapeutic effect for breast cancer brain metastases.
Chemical Properties
Off-white to yellow solid
Uses
2-(Methylsulfonyl)ethylamine Hydrochloride is used in the synthetic preparation of potent and selective PI3Kδ inhibitors.
2-Aminoethylmethylsulfone hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
2-Aminoethylmethylsulfone hydrochloride Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23680
- Advantage
- 75
View Lastest Price from 2-Aminoethylmethylsulfone hydrochloride manufacturers
- Product
- 2-Aminoethylmethylsulfone hydrochloride 104458-24-4
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-16
- Product
- 2-Aminoethylmethylsulfone hydrochloride 104458-24-4
- Price
- US $30.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100 Tons
- Release date
- 2022-03-23
- Product
- 2-Aminoethylmethylsulfone hydrochloride 104458-24-4
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2023-04-11