Description
ChemicalBook > CAS DataBase List > 2-Aminoethylmethylsulfone hydrochloride

2-Aminoethylmethylsulfone hydrochloride

Description
Product Name
2-Aminoethylmethylsulfone hydrochloride
CAS No.
104458-24-4
Chemical Name
2-Aminoethylmethylsulfone hydrochloride
Synonyms
2-Methanesulfonylethan-1-aMine hydrochloride;2-(methylsulfonyl)ethan-1-amine hydrochloride;2-(Methylsulfonyl)Ethylamine HCl;CL126;)ethanamine hydrochL;Lapatinib hyrochloride;Lapatinib Intermediate 1;2-AMINOETHYLMETHYLSULFONE HCL;2-Methane sulfonyl ethyl aMine;2-(Methylsulfonyl)ethanaMine HCl
CBNumber
CB01113134
Molecular Formula
C3H10ClNO2S
Formula Weight
159.63
MOL File
104458-24-4.mol
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2-Aminoethylmethylsulfone hydrochloride Property

Melting point:
168.0 to 172.0 °C
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
InChIKey
AMYYUKGKCJKCBI-UHFFFAOYSA-N
CAS DataBase Reference
104458-24-4(CAS DataBase Reference)
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Safety

HS Code 
29211990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2464
Product name
2-Aminoethyl Methyl Sulfone Hydrochloride
Purity
>98.0%(N)(T)
Packaging
5g
Price
$44
Updated
2024/03/01
TRC
Product number
M339108
Product name
2-(Methylsulfonyl)ethylamineHydrochloride
Packaging
2.5g
Price
$95
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA53226
Product name
2-Aminoethylmethylsulfone Hydrochloride
Packaging
10g
Price
$120
Updated
2021/12/16
Apolloscientific
Product number
OR12674
Product name
2-Aminoethylmethylsulphone hydrochloride
Packaging
10g
Price
$129
Updated
2021/12/16
SynQuest Laboratories
Product number
8163-5-X0
Product name
2-Aminoethylmethylsulfone hydrochloride
Packaging
10g
Price
$152
Updated
2021/12/16
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2-Aminoethylmethylsulfone hydrochloride Chemical Properties,Usage,Production

Description

Lapatinib is a new drug targeted for the treatment of breast cancer developed by GlaxoSmithKline, which was approved for marketing by the US Food and Drug Administration on March 13, 2007. The currently approved indications are advanced mastocarcinoma treated with lapatinib and capecitabine or metastatic breast cancer, and breast cancer patients must be treated first in other first-class drugs. Its trade name is Tykerb in the United States. On December 14, 2007, the European Medicines Agency (EMEA) approved for marketing of lapatinib in Europe, and the trade name is Tyverb. Breast cancer molecular targeted therapy is the treatment for oncogene related with occurrence and development of breast cancer, and for its related expression product. Molecular targeted drugs control the changes of gene expression in the cell through blocking signal transduction of tumor cell or related cell, thereby inhibiting or killing tumor cells.
Lapatinib is a small molecule epidermal growth factor tyrosine kinase inhibitor orally. Clinical trials have shown that lapatinib has a very good clinical effect in patients with HER2 breast cancer who have been resistant to Roche's Herceptin. In vitro, the inhibitory effect of lapatinib on the growth of Her-2 overexpressing breast cancer cell lines was significant. Lapatinib is also highly effective in the Phase I clinical trial of Her-2 overexpression in advanced breast cancer and has no cross-resistance with Herceptin (trastuzumab). Unlike Herceptin (trastuzumab), its structure is small molecules, so it could get through the blood-brain barrier, thereby having a certain therapeutic effect for breast cancer brain metastases.

Chemical Properties

Off-white to yellow solid

Uses

2-(Methylsulfonyl)ethylamine Hydrochloride is used in the synthetic preparation of potent and selective PI3Kδ inhibitors.

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View Lastest Price from 2-Aminoethylmethylsulfone hydrochloride manufacturers

Wuhan wingroup Pharmaceutical Co., Ltd
Product
2-Aminoethylmethylsulfone hydrochloride 104458-24-4
Price
US $30.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 Tons
Release date
2022-03-23
Hebei Guanlang Biotechnology Co,.LTD
Product
2-Aminoethylmethylsulfone hydrochloride 104458-24-4
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2023-04-11
LY Global chemicals co.,ltd .
Product
2-Aminoethylmethylsulfone hydrochloride 104458-24-4
Price
US $0.00/kg
Min. Order
1kg
Purity
98.0%min
Supply Ability
100kg
Release date
2023-03-11

104458-24-4, 2-Aminoethylmethylsulfone hydrochlorideRelated Search:


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