TETRAHYDROFURAN-2-ACETIC ACID ETHYL ESTER
- Product Name
- TETRAHYDROFURAN-2-ACETIC ACID ETHYL ESTER
- CAS No.
- 2434-02-8
- Chemical Name
- TETRAHYDROFURAN-2-ACETIC ACID ETHYL ESTER
- Synonyms
- ethyl 2-(oxolan-2-yl)acetate;ETHYL TETRAHYDROFURAN-2-ACETATE;Tetrahydrofuranaceticacidethylester;Ethyl 2-(tetrahydrofuran-2-yl)acetate;TETRAHYDROFURAN-2-ACETIC ACID ETHYL ESTER
- CBNumber
- CB1483073
- Molecular Formula
- C8H14O3
- Formula Weight
- 158.2
- MOL File
- 2434-02-8.mol
TETRAHYDROFURAN-2-ACETIC ACID ETHYL ESTER Property
- Boiling point:
- 98 °C / 13mmHg
- Density
- 1.03
- refractive index
- 1.4350-1.4390
- storage temp.
- 2-8°C
- form
- clear liquid
- color
- Colorless to Almost colorless
- CAS DataBase Reference
- 2434-02-8
Safety
- HS Code
- 2932190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- T0957
- Product name
- Ethyl Tetrahydrofuran-2-acetate
- Purity
- >98.0%(GC)
- Packaging
- 5mL
- Price
- $210
- Updated
- 2025/07/31
- Product number
- T0957
- Product name
- Ethyl Tetrahydrofuran-2-acetate
- Purity
- >98.0%(GC)
- Packaging
- 25mL
- Price
- $736
- Updated
- 2025/07/31
- Product number
- T293535
- Product name
- Tetrahydro-2-furanaceticAcidEthylEster
- Packaging
- 10g
- Price
- $1320
- Updated
- 2021/12/16
- Product number
- 67194
- Product name
- Tetrahydro-2-furanaceticAcidEthylEster
- Packaging
- 10g
- Price
- $2200
- Updated
- 2021/12/16
- Product number
- 2H23-1-0X
- Product name
- Tetrahydrofuran-2-aceticacidethylester
- Purity
- 95%
- Packaging
- 1g
- Price
- $200
- Updated
- 2021/12/16
TETRAHYDROFURAN-2-ACETIC ACID ETHYL ESTER Chemical Properties,Usage,Production
Uses
Tetrahydro-2-furanacetic Acid Ethyl Ester is used in organic reactions for the opening of cyclic ethers using dimethylboron bromide.
Synthesis
109-99-9
623-73-4
2434-02-8
General procedure for the synthesis of ethyl tetrahydrofuran-2-acetate from tetrahydrofuran and ethyl diazoacetate: first, methyl phenyl diacetate was prepared by the reaction of methyl phenylacetate with p-acetamidobenzenesulfonyl azide. The dried non-homogeneous catalyst (containing 0.02 mmol Cu) was suspended in anhydrous tetrahydrofuran (10 mL containing 100 mg of n-decane as internal standard) and heated to reflux under inert atmosphere. Anhydrous tetrahydrofuran (10 mL) solution of diazo compounds (1 mmol) was slowly added over a period of 2 hours using a syringe pump. After the addition was completed, the reaction mixture was continued to be stirred under reflux conditions for 30 min. Subsequently, the catalyst was removed by filtration and washed with tetrahydrofuran (5 mL). Yield and stereoselectivity were determined by gas chromatography (GC). After addition of diazo compounds and heating at reflux for 2 h, the presence of active copper substances in solution was detected by analytical tests. After drying the catalyst under vacuum, it can be reused under the same conditions. Enantioselectivity was determined by high performance liquid chromatography (HPLC) when the reaction was carried out in the presence of chiral ligands.
References
[1] Journal of the American Chemical Society, 2002, vol. 124, # 6, p. 896 - 897
[2] Inorganic Chemistry, 2015, vol. 54, # 23, p. 11043 - 11045
[3] Dalton Transactions, 2009, # 2, p. 375 - 382
[4] Journal of Catalysis, 2011, vol. 281, # 2, p. 273 - 278
[5] Chemical Science, 2015, vol. 6, # 2, p. 1510 - 1515
TETRAHYDROFURAN-2-ACETIC ACID ETHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
TETRAHYDROFURAN-2-ACETIC ACID ETHYL ESTER Suppliers
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