4'-Aminobenzo-15-crown-5-ether Property

Melting point:

76-78 °C(lit.)

Boiling point:

464.4±45.0 °C(Predicted)

Density 

1.118±0.06 g/cm3(Predicted)

pka

4.63±0.20(Predicted)

form 

powder to crystal

color 

White to Gray to Brown

BRN 

1587285

InChI

InChI=1S/C14H21NO5/c15-12-1-2-13-14(11-12)20-10-8-18-6-4-16-3-5-17-7-9-19-13/h1-2,11H,3-10,15H2

InChIKey

CQNGAZMLFIMLQN-UHFFFAOYSA-N

SMILES

O1C2=CC=C(N)C=C2OCCOCCOCCOCC1

CAS DataBase Reference

60835-71-4

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37

WGK Germany 

3

F 

8-10

HS Code 

29329990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

4'-Aminobenzo-15-crown-5-ether Chemical Properties,Usage,Production

Chemical Properties

4'-Aminobenzo-15-crown-5-ether is a white to grey to brown powder to crystal in appearance, with a density of 1.1 g/cm³, a melting point of 76.0 ~ 80.0 °C, a boiling point of about 464.4° C, and is soluble in water (partially) and chloroform. Sensitive to light and air, store under inert gas.

Uses

4'-Aminobenzo-15-crown-5-ether is an organic heterocyclic compound that is a highly adaptable intermediate in the manufacture of a wide variety of organic compounds such as dyes and polymers. It is also used in the field of materials science and is an essential component in the development of a wide range of materials from nanomaterials to polymers. In scientific studies, the compound has shown inhibitory effects on other enzymes such as acetylcholinesterase and histone deacetylase. In addition, the compound has shown the ability to bind and activate specific receptors such as the 5-HT2A receptor.