Synthesize
ChemicalBook > CAS DataBase List > Sulfanilic acid

Sulfanilic acid

Synthesize
Product Name
Sulfanilic acid
CAS No.
121-57-3
Chemical Name
Sulfanilic acid
Synonyms
SULPHANILIC ACID;4-AMINOBENZENESULFONIC ACID;sulfanilic;P-AMINOBENZENESULFONIC ACID;4-aminobenzenesulfonate;SULFANILLIC ACID;Sulphanillic Acid;ANILINE-4-SULFONIC ACID;SULFANILIC ACID ANHYD PWD;4-AMINOBENZENESULPHONIC ACID
CBNumber
CB1489237
Molecular Formula
C6H7NO3S
Formula Weight
173.19
MOL File
121-57-3.mol
More
Less

Sulfanilic acid Property

Melting point:
>300 °C(lit.)
Boiling point:
288 ℃
Density 
1.485
vapor pressure 
0Pa at 25℃
refractive index 
1.5500 (estimate)
storage temp. 
Store below +30°C.
solubility 
10g/l
pka
3.24(at 25℃)
form 
solid
color 
White to Off-White
PH
2.5 (10g/l, H2O, 20℃)
Water Solubility 
0.1 g/100 mL (20 ºC)
Merck 
14,8926
BRN 
908765
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
HVBSAKJJOYLTQU-UHFFFAOYSA-N
LogP
-2.3 at 25℃
CAS DataBase Reference
121-57-3(CAS DataBase Reference)
NIST Chemistry Reference
Benzenesulfonic acid, 4-amino-(121-57-3)
EPA Substance Registry System
Sulfanilic acid (121-57-3)
More
Less

Safety

Hazard Codes 
C,Xi
Risk Statements 
36/38-43-34
Safety Statements 
26-36/37/39-45-37-24-36/37
RIDADR 
UN 2790 8/PG 3
WGK Germany 
1
RTECS 
WP3895500
Autoignition Temperature
>400 °C
TSCA 
Yes
HS Code 
29214210
Hazardous Substances Data
121-57-3(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 12300 mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.22338
Product name
Sulfanilic acid
Purity
for synthesis
Packaging
100g
Price
$34
Updated
2024/03/01
Sigma-Aldrich
Product number
8.22338
Product name
Sulfanilic acid
Purity
for synthesis
Packaging
1kg
Price
$91.4
Updated
2024/03/01
Sigma-Aldrich
Product number
8.22338
Product name
Sulfanilic acid
Purity
for synthesis
Packaging
50kg
Price
$1040
Updated
2024/03/01
Sigma-Aldrich
Product number
251917
Product name
Sulfanilic acid
Purity
ACS reagent, 99%
Packaging
25g
Price
$33.5
Updated
2024/03/01
Sigma-Aldrich
Product number
39441
Product name
Nitrate Reagent B
Purity
suitable for microbiology
Packaging
100mL
Price
$45.7
Updated
2024/03/01
More
Less

Sulfanilic acid Chemical Properties,Usage,Production

Synthesize

Sulfanilic acid can be used for the determination of nitrite. Biochemical Research. Organic Synthesis. Sulfanilic acid is an important intermediate of sulfonamide drugs. This product has strong antibacterial effect on hemolytic streptococcus, meningitis and coccus, but due to poor efficacy and high toxicity, it is rarely used for oral administration. It is also rarely used. It is used as an intermediate for the synthesis of other sulfonamides, and is also used as a raw material for the synthesis of agricultural "Huangcaoling" abroad. Sulfanilic acid can also be used as an analytical reagent, such as a reagent for the photometric determination of nitrite and sodium nitroferricyanide. For biochemical research, organic synthesis and pharmaceutical industry. Sulfanilic acid is the main raw material for synthesizing sulfonamides. In addition to preparing crystalline sulfonamides for external anti-inflammatory, it can also synthesize other sulfonamides such as sulfamidine, sulfamethoxazine, and sulfamethazine.

Description

Sulfanilic acid (4-amino benzene sulfonic acid ) is an off-white crystalline solid which finds application in quantitative analysis of nitrate and nitrite ions. The solid acid exists as a zwitterion, and has an unusually high melting point.

Chemical Properties

greyish-white crystals or powder

Uses

Sulfanilic Acid (Sulfadimethoxine EP Impurity D) is a toxic metabolite of Tartrazine (T007700). Used as Ehrlich’s reagent, for detecting of nitrites. Antibacterial.

Uses

Sulfanilic acid may be used for the functionalization of single-walled carbon nanotubes (SWNTs) with aryl sulfonate groups.

Uses

A toxic metabolite of Tartrazine (T007700). Used as Ehrlich’s reagent, for detecting of nitrites. Antibacterial.

Application

As the compound readily form diazo compounds, it is used to make dyes and sulpha drugs . This property is also used for the quantitative analysis of nitrate and nitrite ions by diazonium coupling reaction with N-(1-Naphthyl) ethylene diamine , resulting in an azo dye, and the concentration of nitrate or nitrite ions were deduced from the color intensity of the resulting red solution by colorimetry.
It is also used as a standard in combustion analysis.

Definition

ChEBI: An aminobenzenesulfonic acid that is aniline sulfonated at the para-position.

General Description

White powder with faint purple tinge. Grayish-white flat crystals. Becomes anhydrous at around 212°F. Low toxicity (used medicinally).

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Sulfanilic acid is an amino acid. Reacts weakly with both acids and bases.

Fire Hazard

Flash point data for Sulfanilic acid are not available, however Sulfanilic acid is probably combustible.

Synthesis

Sulfanilic acid can be produced by sulfonation of aniline.

Purification Methods

Crystallise the acid (as dihydrate) from boiling water. Dry it at 105o for 2-3hours, then over 90% H2SO4 in a vacuum desiccator. The S-benzylisothiuronium salt has m 187o (from aqueous EtOH). [Beilstein 14 IV 2655.]

Sulfanilic acid Preparation Products And Raw materials

Raw materials

Aniline Sulfuric acid

Preparation Products

Acid Orange 7 ACID YELLOW 17 Acid Orange 156 Direct Red Brown RN AURAMINE O Direct Blending Brilliant Red D-10BL REACTIVE GREEN 19 4-amino-1-naphthol Reactive Dark Blue M-2ge Sumilight Supra Orangl 2GL Tartrazine Methyl Orange CIBACRON BRILLIANT YELLOW 3G-P 4-Chlorobenzenesulfonic acid Fluorescent Brightener VBU DIRECT RED 80 8,8-Dimethoxy-2,6-dimethyloctan-2-ol Direct Blending Brilliant Red D-5BL Piperonyl aldehyde Reactive Red 15 4-Amino-benzenesulfonic acid monosodium salt N-Phenyl-1-naphthylamine 4-Amino-1,3-benzenedisulfonic acid sodium N-benzylsulphanilate C. I. Pigment Red 56 Sunset Yellow FCF Acid Yellow 199 Direct Blend Rubine D-BLL new red REACTIVE RED 4 p-Anisaldehyde Direct Blending Yellow D-3RNL 4-Chlorobenzenesulfonyl chloride Direct Violet 9 Reactive Violet 2 Direct Blending Scarlet D-GLN
More
Less

Sulfanilic acid Suppliers

Austria 1 Belgium 1 Brazil 1 Canada 2 China 378 China Hong Kong 1 Czech Republic 2 Europe 3 France 4 Germany 11 Hungary 1 India 99 Indonesia 1 Japan 11 Mexico 2 Poland 1 Singapore 1 Slovakia 1 South Africa 1 South Korea 4 Spain 3 Switzerland 4 The Netherlands 1 United Kingdom 15 United States 87 Global 636
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14332
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10404
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Cater Chemicals Corp.
Tel
--
Fax
--
Email
info@caterchem.com
Country
United States
ProdList
229
Advantage
58
Noah Chemicals
Tel
--
Fax
--
Email
solutions@noahtech.com
Country
United States
ProdList
881
Advantage
58
Monomer Polymer & Dajac Labs
Tel
--
Fax
--
Email
info@monomerpolymer.com
Country
United States
ProdList
1609
Advantage
58
Wintersun International Inc.
Tel
--
Fax
--
Email
orders@wintersunchem.com
Country
United States
ProdList
191
Advantage
58
Richman Chemical Inc
Tel
--
Fax
--
Email
clk@RichmanChemical.com
Country
United States
ProdList
238
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
GFS Chemicals, Inc.
Tel
--
Fax
--
Email
Development@gfschemicals.com
Country
United States
ProdList
338
Advantage
58
Aozeal Certified Standards (AOCS), Inc.
Tel
--
Fax
--
Email
info@aozeal.com
Country
United States
ProdList
504
Advantage
58
CALSAK CORPORATION
Tel
--
Fax
--
Email
calsak@calsak.com
Country
United States
ProdList
430
Advantage
58
Nation Ford Chemical Co. (NFC)
Tel
--
Fax
--
Email
dicksonj@nationfordchem.com
Country
United States
ProdList
3
Advantage
58
Redox Scientific
Tel
--
Fax
--
Email
info@redoxsci.com
Country
United States
ProdList
2380
Advantage
58
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Sinova Inc.
Tel
--
Fax
--
Email
sales@sinovainc.com
Country
United States
ProdList
4009
Advantage
58
Dudley Chemical Corp.
Tel
--
Fax
--
Email
dudley@dudley-chem.com
Country
United States
ProdList
687
Advantage
64
Charkit Chemical Corporation
Tel
--
Fax
--
Email
sales@charkit.com
Country
United States
ProdList
2993
Advantage
65
American International Chemical, Inc.
Tel
--
Fax
--
Email
info@aicma.com
Country
United States
ProdList
531
Advantage
58
Glentham Life Sciences Ltd
Tel
--
Fax
--
Email
info@glentham.com
Country
United States
ProdList
2026
Advantage
58
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
GFS Chemicals Inc
Tel
--
Fax
--
Email
service@gfschemicals.com
Country
United States
ProdList
2328
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Sisco Research Laboratories Pvt. Ltd.
Tel
--
Fax
--
Email
srlmarketing@dishnetdsl.net
Country
United States
ProdList
1905
Advantage
64
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
ProChem, Inc.
Tel
--
Fax
--
Email
prochem1@aol.com
Country
United States
ProdList
1691
Advantage
66
Advanced Synthesis Technologies
Tel
--
Fax
--
Email
sales@advancedsynthesis.com
Country
United States
ProdList
4775
Advantage
61
Dynemic Products Ltd.
Tel
--
Fax
--
Email
info@dynemic.com
Country
United States
ProdList
51
Advantage
47
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
Barker Industries, Inc.
Tel
--
Fax
--
Email
sales@barkerind.com
Country
United States
ProdList
226
Advantage
51
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
Naugra Export
Tel
--
Fax
--
Country
United States
ProdList
1332
Advantage
47
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
City Chemical LLC
Tel
--
Fax
--
Email
sales@citychemical.com
Country
United States
ProdList
6708
Advantage
72
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
TimTec Corporation
Tel
--
Fax
--
Country
United States
ProdList
1945
Advantage
58
More
Less

View Lastest Price from Sulfanilic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Sulfanilic acid 121-57-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10mt
Release date
2024-10-29
Hebei Yanxi Chemical Co., Ltd.
Product
Sulfanilic acid 121-57-3
Price
US $1.00/kg
Min. Order
1kg
Purity
99.00%
Supply Ability
20tons
Release date
2023-09-08
Hebei Chuanghai Biotechnology Co,.LTD
Product
Sulfanilic acid 121-57-3
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-20

121-57-3, Sulfanilic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate Hyaluronic acid Sulfanilamide 4-Aminobenzoic acid Stearic acid Citric acid 4-Aminobenzaldehyde p-Anisidine Folic acid Ascoric Acid p-[[(4-chlorobutyl)sulphonyl]amino]benzenesulphonamide N-acetylsulphanilic acid 4-(Acetylamino)-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide Sulfadimethoxine-d6 Sulfadimethoxine 4-Amino-2,6-dimethoxypyrimidine 1,3-di(4-sulfamoylphenyl)triazene SULFADIMETHOXINE-D4

  • 4-aminobenzenesulfonate
  • SULFANILIC ACID, ANHYDROUS, REAGENT (ACS)SULFANILIC ACID, ANHYDROUS, REAGENT (ACS)SULFANILIC ACID, ANHYDROUS, REAGENT (ACS)SULFANILIC ACID, ANHYDROUS, REAGENT (ACS)
  • Diazobenzenesulfonic acid test solution(ChP)
  • SULFANILIC ACID ANHYD PWD
  • Sulfanilic acid puriss. p.a., >=99.0% (T)
  • Sulfanilic acid Vetec(TM) reagent grade, 99%
  • BES SODIUM SALT HIGH PURITY GRADE
  • p-Anilinesulfonic acid anhydrous
  • DNA MW MARKER 1KB LADDER
  • 4-SULFOANILINE
  • 4-AMINOBENZENESULPHONIC ACID
  • 4-AMINOBENZENESULFONIC ACID
  • 4-ANILINESULFONIC ACID
  • SUFANILIC ACID
  • SULFANILIC ACID
  • SULFANILIC ACID TS
  • SULFANILLIC ACID
  • SULPHANILIC ACID
  • P-SULFANILIC ACID
  • P-ANILINESULFONIC ACID
  • P-AMINOBENZENESULFONIC ACID
  • NITRATE REAGENT B
  • LB POWDER NON ANIMAL ORIGIN 5X1 L
  • 4-Aminobenzenesulfonic acid Aniline-4-sulfonic acid p-Aminobenzene sulfonic acid anhydrous 4-Sulfoaniline 4-Anilinesulfonic acid p-Anilinesulfonic Acid
  • Sulfanilicacid,anhydrous
  • Sulfanilicacidanhydrous
  • Sulfanilsaeure
  • Sulfanilic acid 99.0+ % for analysis
  • Sulfanilic acid 99+ %
  • Sulphanillic Acid
  • SULFANILIC ACID, 99%, A.C.S. REAGENT
  • SULFANILIC ACID STD SOLUTION 0.1 MOL/L N29, 1 L
  • P-AMINOBENZENS SULFONIC ACID
  • SulphanilicAcidA.R.
  • SulphanilicAcid,>98%
  • SulfanilicAcidMonohydrate
  • SulphanilicAcidGr
  • p-Aminobenzene sulfonic acid anhydrous
  • SULFANILIC ACID ANHYDROUS ACS REAGENT
  • faniL
  • ANILINE-4-SULFONIC ACID
  • ANILINE P-SULFONIC ACID
  • Sulfanilic Acid, Anhydrous, Reagent
  • 4-aminobenzenesulphonic acid,sulphanilic acid
  • Sulfanilic acid solution,4-Aminobenzenesulfonic acid
  • Sulfanilic acid,4-Aminobenzenesulfonic acid, Aniline-4-sulfonic acid
  • Sulfanilic acid, reagent grade, ACS
  • Sulfanilic Acid Solution [for Spray]
  • Sulfanilic Acid (200 mg)
  • Sulfanilic acid, ACS reagent
  • Sulfanilic acid, 99% 100GR
  • Sulfanilic acid (8CI)
  • 1-AMinobenzene-4-sulfonic Acid
  • 4-AMinophenylsulfonic Acid
  • NSC 7170
  • p-Sulfoaniline
  • 4-Aminobenzenesulfonic Acid p-Anilinesulfonic Acid 4-Sulfoaniline
  • SULFANILIC ACID GR FOR ANALYSIS ACS