TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD

ChemicalBook > CAS DataBase List > TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD

TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD

Product Name: TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD
CAS No.: 137076-54-1
Chemical Name: TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD
Synonyms: DOTA-tris(t-Bu ester);TA-DOTA;NH2-PEG4-DOTA-GA;DOTA-tri(t-butyl ester);DOTA-tris(tert-butyl ester) Novabiochem;(4,7,10-Tris-tert-butoxycarbonylmethyl-1,4,7,10tetraaza-cyclododec-1-yl)-acetic acid;2-(4,7,10-TRIS(2-TERT-BUTOXY-2-OXOETHYL)-1,4,7,10-TETRAAZACYCLODODECAN-1-YL)ACETIC ACID;1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 1,4,7-tris(1,1-dimethylethyl) ester;DOTA-Tris(tBu);DOTA-(COOt-Bu)3
CBNumber: CB1497261
Molecular Formula: C28H52N4O8
Formula Weight: 572.73
MOL File: 137076-54-1.mol

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TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD Property

Melting point:: 129-131℃
Boiling point:: 632.1±55.0 °C(Predicted)
Density: 1.079
storage temp.: Inert atmosphere,2-8°C
solubility: Aqueous Base (Slightly), Chloroform (Slightly), DMSO (Slightly),Methanol(Slightly)
form: Solid
pka: 4.24±0.10(Predicted)
color: Pale Beige
InChI: InChI=1S/C28H52N4O8/c1-26(2,3)38-23(35)19-30-12-10-29(18-22(33)34)11-13-31(20-24(36)39-27(4,5)6)15-17-32(16-14-30)21-25(37)40-28(7,8)9/h10-21H2,1-9H3,(H,33,34)
InChIKey: RVUXZXMKYMSWOM-UHFFFAOYSA-N
SMILES: N1(CC(OC(C)(C)C)=O)CCN(CC(O)=O)CCN(CC(OC(C)(C)C)=O)CCN(CC(OC(C)(C)C)=O)CC1
CAS DataBase Reference: 137076-54-1

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 75061
Product name: Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate
Purity: ≥95.0%(CHN)
Packaging: 100mg
Price: $183
Updated: 2024/03/01

TCI Chemical

Product number: T2642
Product name: Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate
Purity: >97.0%(T)
Packaging: 100mg
Price: $165
Updated: 2024/03/01

TCI Chemical

Product number: T2642
Product name: Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate
Purity: >97.0%(T)
Packaging: 1g
Price: $679
Updated: 2024/03/01

TRC

Product number: D494855
Product name: DOTA-tris(t-Buester)(~90%)
Packaging: 25mg
Price: $85
Updated: 2021/12/16

Chem-Impex

Product number: 14713
Product name: 4,7,10-Tri-(-butyloxycarbonylmethyl)- 1,4,7,10-tetraazacyclododecan-1-yl-acetic acid
Purity: ≥ 98% (HPLC)
Packaging: 250MG
Price: $105
Updated: 2021/12/16

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TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD Chemical Properties,Usage,Production

Description

DOTA(OtBu)3 contains a DOTA moiety with t-butyl groups which can be used as a chelating agent for cations and is commonly used for imaging diagnostics. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

DOTA-tris (t-Bu ester), is a Bifunctional chelator, that can be used in the preparation of gadolinium complexes as MRI blood contrast agents.

Uses

Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate (tri BOC-DOTA) can be employed as a reactant to prepare:

Gadolinium ion functionalized with DOTA-LAE (lactobionic acid-ethylenediamine), which is used as a contrast agent for magnetic resonance imaging (MRI).
DOTA-conjugates of ursolic acid and ZD₂ peptide ⁶⁴Cu-DOTA conjugates.

TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD Preparation Products And Raw materials

Raw materials

Potassium carbonate Cyclen Triethylamine Bromoacetic acid tert-Butyl bromoacetate

Preparation Products

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View Lastest Price from TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: DOTA-(COOt-Bu)3 137076-54-1
Price: US $0.00/g
Min. Order: 10g
Purity: >95.00%
Supply Ability: 10g
Release date: 2024-04-01

Hebei Mojin Biotechnology Co., Ltd

Product: TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD 137076-54-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-11-15

Hebei Guanlang Biotechnology Co., Ltd.

Product: TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD 137076-54-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2022-09-28

137076-54-1, TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODODRelated Search:

Tri-tert-butylphosphine TRI-TERT-BUTYLPHOSPHONIUM TETRAPHENYLBORATE Tri-tert-butylphosphine tetrafluoroborate Methyl trichloroacetate 1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetate HydrobroMide TRI-T-BUTYL 1 4 7 10-TETRAAZACYCLODODECA 1,4,7-Tris(ethoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane DOTA TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD 1,7-Bis(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane Cyclen

DOTA-tris(t-Bu ester)

Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate DOTA-tris(tBu)ester

2-[4,7,10-tris[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetic acid

(4,7,10-Tris-tert-butoxycarbonylmethyl-1,4,7,10tetraaza-cyclododec-1-yl)-acetic acid

Tri-<i>tert</i>-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate

DOTA-tris(tert-butyl ester) Novabiochem

1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 1,4,7-tris(1,1-dimethylethyl) ester

TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD

TRI-TERT-BUTYL 1,4,7,10-TETRAAZACYCLODODECANE-TETRAACETATE

2-(4,7,10-tris(2-tert-butoxy-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acet

1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid Tri-tert-butyl Ester

1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, tris(1,1-diMethylethyl) ester

2-(4,7,10-TRIS(2-TERT-BUTOXY-2-OXOETHYL)-1,4,7,10-TETRAAZACYCLODODECAN-1-YL)ACETIC ACID

1,4,7,10-Tetraazacyclododecane-1,4,7-tris-tert-butyl acetate-10-acetic acid

DOTA-tris (t-Bu ester)(B-260)

1,4,7 -Boc-1,4,7,10- tetraazacyclododecane Cyclododecane -10- acid

S-2-(4-Isothiocyanatobenzyl)-1, 4, 7, 10-tetraazacyclododecane tetraacetic acid

NH2-PEG4-DOTA-GA

TA-DOTA

DOTA-tris(t-Butyl ester)

DOTA-tris (t-Bu ester) (~90%)

2-[4,7,10-tris(2-tert-butoxy-2-oxo-ethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetic acid

DOTA-(COOt-Bu)3

TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD USP/EP/BP

DOTA-tri(t-butyl ester)

2-{4,7,1-tris[2-(tert-butoxy)-2-oxoethyl]-1,4,7,1-tetraazacyclododecan-1-yl}acetic acid

Tri-tert-butyl 1,4,7,1-tetraazacyclododecane-1,4,7,1-tetraacetate

Tianfu Chem TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD

1,4,7-tris(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane-10-acetic acid

DOTA-tris(tert-butyl ester)

2-[4,7,10-tris[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]aceticaci

Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,11-tetraacetate

DOTA tri(tert-butyl) ester

DOTA-Tris(tBu)

137076-54-1

C28H52N4O8

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