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Tinoridine

Product Name
Tinoridine
CAS No.
24237-54-5
Chemical Name
Tinoridine
Synonyms
6H;y-3642;tinoridine;7H-thieno[2;Tinoridine USP/EP/BP;Nonflamin (free base);ethyl 2-amino-6-benzyl-4H;Cholecalciferol Impurity 26;Thieno(2,3-c)pyridine-3-carboxylic acid, 2-amin;2-AMINO-3-ETHOXY-CARBONYL-6-BENZYL-4,5,6,7-TETRAHYDROTHIEN.
CBNumber
CB1507182
Molecular Formula
C17H20N2O2S
Formula Weight
316.42
MOL File
24237-54-5.mol
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Tinoridine Property

Melting point:
112-113°C
Boiling point:
493.5±45.0 °C(Predicted)
Density 
1.256±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly)
form 
Solid
pka
6.29±0.20(Predicted)
color 
Light Yellow
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Safety

HazardClass 
IRRITANT
HS Code 
2934999090
Toxicity
LD50 in mice, rats (mg/kg): 5400, >10200 orally; 1600, 1250 i.p. (Nakanishi, 1970)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
E897810
Product name
Ethyl2-Amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate(Tinoridine)
Packaging
250mg
Price
$55
Updated
2021/12/16
TRC
Product number
E897810
Product name
Ethyl2-Amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate(Tinoridine)
Packaging
1g
Price
$105
Updated
2021/12/16
TRC
Product number
E897810
Product name
Ethyl2-Amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate(Tinoridine)
Packaging
2.5g
Price
$180
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0015826
Product name
TINORIDINE
Purity
95.00%
Packaging
0.5G
Price
$605
Updated
2021/12/16
AK Scientific
Product number
8166AD
Product name
Ethyl2-amino-6-benzyl-4,5,6,7-tetrahydrothieno-[2,3-c]pyridine-3-carboxylate
Packaging
1g
Price
$75
Updated
2021/12/16
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Tinoridine Chemical Properties,Usage,Production

Originator

Nonflamin,Yoshitomi,Japan,1971

Uses

Ethyl 2-Amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (Tinoridine) targets pantothenate synthetase which plays a significant role in the biosynthesis of pantothenate in Mycobacterium tuberculosis (MTB).

Definition

ChEBI: Tinoridine is a thienopyridine.

Manufacturing Process

A solution of 1-benzyl-4-piperidone, ethyl cyanoacetate, powdery sulfur and morpholine in ethanol is heated moderately under reflux for about 20 minutes to dissolve the powdery sulfur. The mixture is heated under reflux for one further hour to complete the reaction. On standing at room temperature, the mixture yields a precipitate. The precipitate is collected by filtration, washed well with methanol and recrystallized from methanol to give 2-amino-6- benzyl-3-ethoxycarbonyl-4,5,6,7-tetrahydrothieno(2,3-c)-pyridine as almost colorless needles melting at 112° to 113°C.

brand name

Tinoridine Hydrochloride is JAN.

Therapeutic Function

Antiinflammatory

Tinoridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Tinoridine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Tinoridine 24237-54-5
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-04-29
Dideu Industries Group Limited
Product
Tinoridine 24237-54-5
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-15

24237-54-5, TinoridineRelated Search:


  • 2-amino-6-(phenylmethyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-ium-3-carboxylic acid ethyl ester
  • 2-AMINO-3-ETHOXY-CARBONYL-6-BENZYL-4,5,6,7-TETRAHYDROTHIEN.
  • Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
  • tinoridine
  • y-3642
  • 2-amino-3-aethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridin
  • 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine
  • 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine-3-carboxylicacidet
  • 3-c)pyridine-3-carboxylicacid,4,5,6,7-tetrahydro-2-amino-6-benzyl-thieno(
  • 2-Amino-6-benzyl-3-(ethoxycarbonyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine, Tinoridine
  • Thieno[2,3-c]pyridine-3-carboxylic acid, 2-aMino-4,5,6,7-tetrahydro-6-(phenylMethyl)-, ethyl ester
  • 2-amino-6-(benzyl)-5,7-dihydro-4H-thieno[5,4-c]pyridine-3-carboxylic acid ethyl ester
  • 2-amino-6-(phenylmethyl)-5,7-dihydro-4H-thieno[5,4-c]pyridine-3-carboxylic acid ethyl ester
  • ethyl 2-amino-6-(phenylmethyl)-5,7-dihydro-4H-thieno[5,4-c]pyridine-3-carboxylate
  • Nonflamin (free base)
  • Thieno(2,3-c)pyridine-3-carboxylic acid, 2-amin
  • Thieno(2,3-c)pyridine-3-carboxylic acid, 2-amino-4,5,6,7-tetrahydro-6-(phenylmethyl)-, ethyl ester (9CI)
  • Tinoridine USP/EP/BP
  • 6H
  • 7H-thieno[2
  • ethyl 2-amino-6-benzyl-4H
  • ethyl 2-amino-6-benzyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate
  • Cholecalciferol Impurity 26
  • 24237-54-5