2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol hydrochloride

Product Name: 2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol hydrochloride
CAS No.: 2369053-68-7
Chemical Name: 2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol hydrochloride
Synonyms: 2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol hydrochloride;2-(6-Amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol dihydrochloride;SMARCABD ligand 1 for Protac dihydrochloride,SMARCA BD ligand 1 for Protac dihydrochloride
CBNumber: CB15433396
Molecular Formula: C14H18ClN5O
Formula Weight: 307.77862
MOL File: 2369053-68-7.mol

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2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol hydrochloride Property

form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol hydrochloride Chemical Properties,Usage,Production

Uses

SMARCA-BD ligand 1 for PROTAC dihydrochloride is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC[1].

References

[1] Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680. DOI:10.1038/s41589-019-0294-6

2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol hydrochloride Suppliers

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2369053-68-7, 2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol hydrochlorideRelated Search:

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2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol hydrochloride

SMARCABD ligand 1 for Protac dihydrochloride,SMARCA BD ligand 1 for Protac dihydrochloride

2-(6-Amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol dihydrochloride

2369053-68-7