ChemicalBook > CAS DataBase List > SMI-16a
SMI-16a
- Product Name
- SMI-16a
- CAS No.
- 587852-28-6
- Chemical Name
- SMI-16a
- Synonyms
- SMI-16a;SMI-16A;SMI 16A;SMI16A;PIM1/2 Kinase Inhibitor VI;SMI-16a(PIM1/2 Kinase Inhibitor VI);5-(4-propoxybenzylidene)thiazolidine-2,4-dione;2,4-Thiazolidinedione, 5-[(4-propoxyphenyl)methylene]-;SMI-16a,SMI 16a,inhibit,SMI16a,Pim,Inhibitor,Pim kinases
- CBNumber
- CB63313558
- Molecular Formula
- C13H13NO3S
- Formula Weight
- 263.31
- MOL File
- 587852-28-6.mol
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SMI-16a Property
- Melting point:
- 186.3-188.4 °C
- Density
- 1.303±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- Ethanol:3.0(Max Conc. mg/mL);11.39(Max Conc. mM)
- form
- A solid
- pka
- 7.27±0.20(Predicted)
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 29456
- Product name
- SMI-16a
- Packaging
- 5mg
- Price
- $93
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29456
- Product name
- SMI-16a
- Packaging
- 25mg
- Price
- $365
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29456
- Product name
- SMI-16a
- Packaging
- 10mg
- Price
- $166
- Updated
- 2024/03/01
ChemScene
- Product number
- CS-6913
- Product name
- SMI-16a
- Purity
- 99.70%
- Packaging
- 10mg
- Price
- $216
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-6913
- Product name
- SMI-16a
- Purity
- 99.70%
- Packaging
- 5mg
- Price
- $120
- Updated
- 2021/12/16
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SMI-16a Chemical Properties,Usage,Production
Description
SMI-16a is a Pim-1 kinase inhibitor (IC50 = 63 nM). It is selective for Pim-1 over a panel of 60 kinases. SMI-16a (5 μM) inhibits phosphorylation of the Pim-1 target protein Bad in DU145-Pim cells and inhibits the growth of PC3, DU145, LNCaP, K562, and MV4-11 cancer cells. It induces apoptosis and cell cycle arrest at the G1 phase in DU145 cells.
SMI-16a Preparation Products And Raw materials
Raw materials
Preparation Products
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SMI-16a Suppliers
- Tel
- 025-66099280 17798518460
- Fax
- (1)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 19915
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- 55
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- 021-65675885 18964387627
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- 021-65675885
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- China
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- 021-61312847; 18021002903
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- QQ:3008007432
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- China
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- 15076683720
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- 022-23754520
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- 177-54423994 17754423994
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- QQ:2853530913
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- China
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- 021-2022843681 15618226720
- Fax
- +86-21-51601218
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- China
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- 010-50973130 4009686088
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- China
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- 571-89925085
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- 0086-571-89925065
- sales@amadischem.com
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- China
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- 010-60605840 18892239720
- Fax
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
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- 12306
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- Tel
- 021-58111628 15800915896
- Fax
- QQ 3285589261
- sales@twochem.com
- Country
- China
- ProdList
- 1788
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View Lastest Price from SMI-16a manufacturers
Career Henan Chemical Co
- Product
- SMI-16a 587852-28-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 20kg
- Release date
- 2019-12-23