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SMI-16a

Product Name
SMI-16a
CAS No.
587852-28-6
Chemical Name
SMI-16a
Synonyms
SMI-16a;SMI-16A;SMI 16A;SMI16A;PIM1/2 Kinase Inhibitor VI;SMI-16a(PIM1/2 Kinase Inhibitor VI);5-(4-propoxybenzylidene)thiazolidine-2,4-dione;2,4-Thiazolidinedione, 5-[(4-propoxyphenyl)methylene]-;SMI-16a,SMI 16a,inhibit,SMI16a,Pim,Inhibitor,Pim kinases
CBNumber
CB63313558
Molecular Formula
C13H13NO3S
Formula Weight
263.31
MOL File
587852-28-6.mol
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SMI-16a Property

Melting point:
186.3-188.4 °C
Density 
1.303±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
Ethanol:3.0(Max Conc. mg/mL);11.39(Max Conc. mM)
form 
A solid
pka
7.27±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29456
Product name
SMI-16a
Packaging
5mg
Price
$93
Updated
2024/03/01
Cayman Chemical
Product number
29456
Product name
SMI-16a
Packaging
25mg
Price
$365
Updated
2024/03/01
Cayman Chemical
Product number
29456
Product name
SMI-16a
Packaging
10mg
Price
$166
Updated
2024/03/01
ChemScene
Product number
CS-6913
Product name
SMI-16a
Purity
99.70%
Packaging
10mg
Price
$216
Updated
2021/12/16
ChemScene
Product number
CS-6913
Product name
SMI-16a
Purity
99.70%
Packaging
5mg
Price
$120
Updated
2021/12/16
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SMI-16a Chemical Properties,Usage,Production

Description

SMI-16a is a Pim-1 kinase inhibitor (IC50 = 63 nM). It is selective for Pim-1 over a panel of 60 kinases. SMI-16a (5 μM) inhibits phosphorylation of the Pim-1 target protein Bad in DU145-Pim cells and inhibits the growth of PC3, DU145, LNCaP, K562, and MV4-11 cancer cells. It induces apoptosis and cell cycle arrest at the G1 phase in DU145 cells.

SMI-16a Preparation Products And Raw materials

Raw materials

Preparation Products

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SMI-16a Suppliers

China 47 India 1 United States 5 USA 1 Global 54
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
3501
Advantage
55
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
info@SuperLan-chem.com
Country
China
ProdList
9754
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29796
Advantage
68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12308
Advantage
58
Twochem Co.Ltd.
Tel
021-58111628 15800915896
Fax
QQ 3285589261
Country
China
ProdList
1988
Advantage
58
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View Lastest Price from SMI-16a manufacturers

Career Henan Chemical Co
Product
SMI-16a 587852-28-6
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
20kg
Release date
2019-12-23

587852-28-6, SMI-16aRelated Search:


  • SMI-16a
  • PIM1/2 Kinase Inhibitor VI
  • SMI-16a(PIM1/2 Kinase Inhibitor VI)
  • SMI-16A;SMI 16A;SMI16A
  • 2,4-Thiazolidinedione, 5-[(4-propoxyphenyl)methylene]-
  • SMI-16a,SMI 16a,inhibit,SMI16a,Pim,Inhibitor,Pim kinases
  • 5-(4-propoxybenzylidene)thiazolidine-2,4-dione
  • 587852-28-6