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SMI-16a

Product Name
SMI-16a
CAS No.
587852-28-6
Chemical Name
SMI-16a
Synonyms
SMI-16a;SMI-16A;SMI 16A;SMI16A;PIM1/2 Kinase Inhibitor VI;SMI-16a(PIM1/2 Kinase Inhibitor VI);5-(4-propoxybenzylidene)thiazolidine-2,4-dione;2,4-Thiazolidinedione, 5-[(4-propoxyphenyl)methylene]-;SMI-16a,SMI 16a,inhibit,SMI16a,Pim,Inhibitor,Pim kinases
CBNumber
CB63313558
Molecular Formula
C13H13NO3S
Formula Weight
263.31
MOL File
587852-28-6.mol
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SMI-16a Property

Melting point:
186.3-188.4 °C
Density 
1.303±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
Ethanol:3.0(Max Conc. mg/mL);11.39(Max Conc. mM)
form 
A solid
pka
7.27±0.20(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29456
Product name
SMI-16a
Packaging
5mg
Price
$93
Updated
2024/03/01
Cayman Chemical
Product number
29456
Product name
SMI-16a
Packaging
25mg
Price
$365
Updated
2024/03/01
Cayman Chemical
Product number
29456
Product name
SMI-16a
Packaging
10mg
Price
$166
Updated
2024/03/01
ChemScene
Product number
CS-6913
Product name
SMI-16a
Purity
99.70%
Packaging
5mg
Price
$120
Updated
2021/12/16
Adipogen Life Sciences
Product number
CDX-P0110-M010
Product name
5-[(4-Propyloxyphenyl)methylene]2,4-thiazolidinedione
Purity
≥95%(HPLC)
Packaging
10mg
Price
$141
Updated
2021/12/16
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SMI-16a Chemical Properties,Usage,Production

Description

SMI-16a is a Pim-1 kinase inhibitor (IC50 = 63 nM). It is selective for Pim-1 over a panel of 60 kinases. SMI-16a (5 μM) inhibits phosphorylation of the Pim-1 target protein Bad in DU145-Pim cells and inhibits the growth of PC3, DU145, LNCaP, K562, and MV4-11 cancer cells. It induces apoptosis and cell cycle arrest at the G1 phase in DU145 cells.

SMI-16a Preparation Products And Raw materials

Raw materials

Preparation Products

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SMI-16a Suppliers

China 48 India 1 United States 5 USA 1 Global 55
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View Lastest Price from SMI-16a manufacturers

Career Henan Chemical Co
Product
SMI-16a 587852-28-6
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
20kg
Release date
2019-12-23

587852-28-6, SMI-16aRelated Search:

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  • SMI-16a
  • PIM1/2 Kinase Inhibitor VI
  • SMI-16a(PIM1/2 Kinase Inhibitor VI)
  • SMI-16A;SMI 16A;SMI16A
  • 2,4-Thiazolidinedione, 5-[(4-propoxyphenyl)methylene]-
  • SMI-16a,SMI 16a,inhibit,SMI16a,Pim,Inhibitor,Pim kinases
  • 5-(4-propoxybenzylidene)thiazolidine-2,4-dione
  • 587852-28-6