SMI-16a

ChemicalBook > CAS DataBase List > SMI-16a

Product Name: SMI-16a
CAS No.: 587852-28-6
Chemical Name: SMI-16a
Synonyms: SMI-16a;SMI-16A;SMI 16A;SMI16A;PIM1/2 Kinase Inhibitor VI;SMI-16a(PIM1/2 Kinase Inhibitor VI);5-(4-propoxybenzylidene)thiazolidine-2,4-dione;2,4-Thiazolidinedione, 5-[(4-propoxyphenyl)methylene]-;SMI-16a,SMI 16a,inhibit,SMI16a,Pim,Inhibitor,Pim kinases
CBNumber: CB63313558
Molecular Formula: C13H13NO3S
Formula Weight: 263.31
MOL File: 587852-28-6.mol

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SMI-16a Property

Melting point:: 186.3-188.4 °C
Density: 1.303±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: Ethanol:3.0(Max Conc. mg/mL);11.39(Max Conc. mM)
form: A solid
pka: 7.27±0.20(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29456
Product name: SMI-16a
Packaging: 5mg
Price: $93
Updated: 2024/03/01

Cayman Chemical

Product number: 29456
Product name: SMI-16a
Packaging: 25mg
Price: $365
Updated: 2024/03/01

Cayman Chemical

Product number: 29456
Product name: SMI-16a
Packaging: 10mg
Price: $166
Updated: 2024/03/01

ChemScene

Product number: CS-6913
Product name: SMI-16a
Purity: 99.70%
Packaging: 5mg
Price: $120
Updated: 2021/12/16

Adipogen Life Sciences

Product number: CDX-P0110-M010
Product name: 5-[(4-Propyloxyphenyl)methylene]2,4-thiazolidinedione
Purity: ≥95%(HPLC)
Packaging: 10mg
Price: $141
Updated: 2021/12/16

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SMI-16a Chemical Properties,Usage,Production

Description

SMI-16a is a Pim-1 kinase inhibitor (IC₅₀ = 63 nM). It is selective for Pim-1 over a panel of 60 kinases. SMI-16a (5 μM) inhibits phosphorylation of the Pim-1 target protein Bad in DU145-Pim cells and inhibits the growth of PC3, DU145, LNCaP, K562, and MV4-11 cancer cells. It induces apoptosis and cell cycle arrest at the G₁ phase in DU145 cells.

SMI-16a Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from SMI-16a manufacturers

Career Henan Chemical Co

Product: SMI-16a 587852-28-6
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 20kg
Release date: 2019-12-23

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SMI-16a

PIM1/2 Kinase Inhibitor VI

SMI-16a(PIM1/2 Kinase Inhibitor VI)

SMI-16A;SMI 16A;SMI16A

2,4-Thiazolidinedione, 5-[(4-propoxyphenyl)methylene]-

SMI-16a,SMI 16a,inhibit,SMI16a,Pim,Inhibitor,Pim kinases

5-(4-propoxybenzylidene)thiazolidine-2,4-dione

587852-28-6